Detroit Pistons vs Philadelphia 76ers Prediction & Picks - NBA

USA - NBA

Detroit Pistons
11/4/26 19:00
Philadelphia 76ers

Prediction:

 

76ers (+1.5) cover the spread

−106
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 by Paul Tamayo | in NBA Picks

The Philadelphia 76ers (7-1) visit the Detroit Pistons (6-1) for an NBA regular season game on Tuesday, November 3, at Little Caesars Arena.

The top two teams in the Eastern Conference face off for the second time early this season. In their first matchup on October 24, the Pistons defeated the Sixers, 106-93. Cade Cunningham put in an all-around outing of 26 points, 8 rebounds, and 8 assists. 

That loss to the Pistons was the Sixers' only defeat so far this season. They have since won four straight games, including a most recent 126-107 win over the Chicago Bulls.  

Offense hasn't been very good for the Sixers, but they're winning mostly on the defensive end of the floor. They're currently ranked second in the league in defensive rating (105.4).

Moreover, the Sixers head into Tuesday's rematch with a healthy trio of Tyrese Maxey, Joel Embiid, and LeBron James.

As for the Pistons, they have won three straight games, including a 124-91 victory over the Charlotte Hornets on Sunday. Cunningham topscored again for Detroit with 33 markers, while Duncan Robinson chipped in six three-pointers on his way to 24 points.

The Pistons have the best defensive rating in the league (102.4), but they're missing their injured starting center Jalen Duren.

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Detroit Pistons vs Philadelphia 76ers Form

Table

Teams % P W L Series
1 Philadelphia 76ers
0.875 8 7 1 4
3 Detroit Pistons
0.857 7 6 1 3

Detroit Pistons and Philadelphia 76ers Latest Matches

Detroit Pistons
Detroit Pistons Latest matches
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 2, 2026 - NBA

Charlotte Hornets
91 :  124
Detroit Pistons

Oct 30, 2026 - NBA

Brooklyn Nets
94 :  110
Detroit Pistons

Oct 28, 2026 - NBA

Detroit Pistons
97 :  89
Charlotte Hornets

Oct 27, 2026 - NBA

New York Knicks
111 :  97
Detroit Pistons

Oct 25, 2026 - NBA

Philadelphia 76ers
93 :  106
Detroit Pistons

Oct 23, 2026 - NBA

Miami Heat
111 :  128
Detroit Pistons
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Oct 28, 2026 - NBA

Detroit Pistons
97 :  89
Charlotte Hornets

Oct 20, 2026 - NBA

Detroit Pistons
121 :  113
Boston Celtics

Jul 15, 2026 - NBA Summer League

Detroit Pistons
88 :  100
Phoenix Suns

Jul 12, 2026 - NBA Summer League

Detroit Pistons
103 :  94
Cleveland Cavaliers

May 17, 2026 - NBA

Detroit Pistons
94 :  125
Cleveland Cavaliers

May 13, 2026 - NBA

Detroit Pistons
113 :  117
Cleveland Cavaliers
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 2, 2026 - NBA

Charlotte Hornets
91 :  124
Detroit Pistons

Oct 30, 2026 - NBA

Brooklyn Nets
94 :  110
Detroit Pistons

Oct 27, 2026 - NBA

New York Knicks
111 :  97
Detroit Pistons

Oct 25, 2026 - NBA

Philadelphia 76ers
93 :  106
Detroit Pistons

Oct 23, 2026 - NBA

Miami Heat
111 :  128
Detroit Pistons

Jul 17, 2026 - NBA Summer League

Miami Heat
101 :  87
Detroit Pistons
Philadelphia 76ers
Philadelphia 76ers Latest matches
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 2, 2026 - NBA

Philadelphia 76ers
126 :  107
Chicago Bulls

Oct 31, 2026 - NBA

Charlotte Hornets
104 :  109
Philadelphia 76ers

Oct 30, 2026 - NBA

Philadelphia 76ers
98 :  93
New York Knicks

Oct 28, 2026 - NBA

Indiana Pacers
109 :  114
Philadelphia 76ers

Oct 25, 2026 - NBA

Philadelphia 76ers
93 :  106
Detroit Pistons

Oct 24, 2026 - NBA

Philadelphia 76ers
127 :  116
Milwaukee Bucks
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 2, 2026 - NBA

Philadelphia 76ers
126 :  107
Chicago Bulls

Oct 30, 2026 - NBA

Philadelphia 76ers
98 :  93
New York Knicks

Oct 25, 2026 - NBA

Philadelphia 76ers
93 :  106
Detroit Pistons

Oct 24, 2026 - NBA

Philadelphia 76ers
127 :  116
Milwaukee Bucks

Oct 22, 2026 - NBA

Philadelphia 76ers
114 :  106
Cleveland Cavaliers

Jul 15, 2026 - NBA Summer League

Philadelphia 76ers
92 :  99
Orlando Magic
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Oct 31, 2026 - NBA

Charlotte Hornets
104 :  109
Philadelphia 76ers

Oct 28, 2026 - NBA

Indiana Pacers
109 :  114
Philadelphia 76ers

Oct 20, 2026 - NBA

New York Knicks
100 :  106
Philadelphia 76ers

Jul 18, 2026 - NBA Summer League

Milwaukee Bucks
96 :  94
Philadelphia 76ers

Jul 14, 2026 - NBA Summer League

Houston Rockets
90 :  64
Philadelphia 76ers

May 6, 2026 - NBA

New York Knicks
108 :  102
Philadelphia 76ers

Detroit Pistons against Philadelphia 76ers : Head to Head (H2H)

Detroit Pistons

83 %

Philadelphia 76ers

17 %

Oct 25, 2026 - NBA

Philadelphia 76ers
93 :  106
Detroit Pistons

Jul 9, 2026 - NBA Summer League

Philadelphia 76ers
101 :  93
Detroit Pistons

Apr 4, 2026 - NBA

Philadelphia 76ers
93 :  116
Detroit Pistons

Mar 12, 2026 - NBA

Detroit Pistons
131 :  109
Philadelphia 76ers

Nov 14, 2025 - NBA

Detroit Pistons
114 :  105
Philadelphia 76ers

Nov 9, 2025 - NBA

Philadelphia 76ers
108 :  111
Detroit Pistons
Detroit Pistons vs Philadelphia 76ers Picks

Players list

Detroit Pistons
Detroit Pistons
J. Collins A. Thompson

C. Cunningham

P. Reed

D. Robinson

Philadelphia 76ers
Philadelphia 76ers
J. Brown J. Embiid

T. Maxey

V. Edgecombe

L. James

Substitutes

Detroit Pistons
Detroit Pistons
K. Huerter T. Smith J. Green J. Duren

E. Okorie

I. Joe

D. Jenkins

C. Lanier

T. Prince

R. Holland

Philadelphia 76ers
Philadelphia 76ers
A. Hukporti D. Wade A. Bona R. Rupert

K. Caldwell-Pope

A. Simons

J. Edwards

L. Philon

J. Walker

D. Barlow

Detroit Pistons - Philadelphia 76ers Key Points

  1. The Sixers are coming off a 126-107 win over the Chicago Bulls.
  2. The Sixers have won four straight games.
  3. The Sixers have the second-best defensive rating in the league.
  4. The Pistons are missing Jalen Duren and Isaiah Joe.

Our Detroit Pistons vs Philadelphia 76ers Prediction

The Pistons defeated the Sixers by 13 points in their first game, but Tuesday's rematch could be a different ball game. Philly has won four straight games, and their star trio is all healthy.

Meanwhile, the Pistons are missing their All-Star center Jalen Duren. The Pistons are still the slight favorites, but the Sixers should keep this game close. Our prediction for the Detroit Pistons vs Philadelphia 76ers match is: 76ers (+1.5) cover the spread.

Prediction:

 

76ers (+1.5) cover the spread

−106
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.