Iowa Hawkeyes vs Ohio State Buckeyes Prediction & Picks - NCAA

USA - NCAA

Iowa Hawkeyes
10/3/26 15:30
Ohio State Buckeyes

Prediction:

 

Over 45.5 Total Points

-110
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 by Matt Lowrimore | in NCAA Picks

Week 5 of the College Football season continues on Saturday with a massive slate of games, one of which will feature a Big Ten matchup between the 5th-ranked Ohio State Buckeyes and the 14th-ranked Iowa Hawkeyes. Let’s take a look at the match statistics and predictions for this game between the Buckeyes and the Hawkeyes.

Ohio State enters this game with a record of 3-1 and 1-0 in the Big Ten. The Buckeyes are coming off a 42-19 win over the Illinois Fighting Illini in Week 4, a game where they produced 518 yards of offense and allowed 462 yards. One thing has been consistent for the Buckeyes this season is that all of their games have had plenty of points scored. This looks likely to continue, even against an Iowa offense that is not known for its efficiency. 

As for Iowa, they enter this game with a record of 4-0 and 1-0 in the Big Ten. The Hawkeyes are coming off a 20-19 win against Michigan in Week 4, in which they scored on the game’s final play to sneak past the Wolverines. Like in past seasons, the Hawkeyes’ focus is on defense, but against the Buckeyes, they are likely to struggle.

Iowa Hawkeyes vs Ohio State Buckeyes Form

Table

Iowa Hawkeyes and Ohio State Buckeyes Latest Matches

Iowa Hawkeyes
Iowa Hawkeyes Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Sep 26, 2026 - NCAA

Michigan Wolverines
19 :  20
Iowa Hawkeyes

Sep 19, 2026 - NCAA

Iowa Hawkeyes
55 :  0
Northern Iowa Panthers

Sep 12, 2026 - NCAA

Iowa Hawkeyes
16 :  13
Iowa State Cyclones

Sep 5, 2026 - NCAA

Iowa Hawkeyes
40 :  0
Northern Illinois Huskies

Dec 31, 2025 - NCAA Division I, FBS, Playoffs

Vanderbilt Commodores
27 :  34
Iowa Hawkeyes

Nov 28, 2025 - NCAA

Nebraska Cornhuskers
16 :  40
Iowa Hawkeyes
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 19, 2026 - NCAA

Iowa Hawkeyes
55 :  0
Northern Iowa Panthers

Sep 12, 2026 - NCAA

Iowa Hawkeyes
16 :  13
Iowa State Cyclones

Sep 5, 2026 - NCAA

Iowa Hawkeyes
40 :  0
Northern Illinois Huskies

Nov 22, 2025 - NCAA

Iowa Hawkeyes
20 :  17
Michigan State Spartans

Nov 8, 2025 - NCAA

Iowa Hawkeyes
16 :  18
Oregon Ducks

Oct 25, 2025 - NCAA

Iowa Hawkeyes
41 :  3
Minnesota Golden Gophers
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 26, 2026 - NCAA

Michigan Wolverines
19 :  20
Iowa Hawkeyes

Dec 31, 2025 - NCAA Division I, FBS, Playoffs

Vanderbilt Commodores
27 :  34
Iowa Hawkeyes

Nov 28, 2025 - NCAA

Nebraska Cornhuskers
16 :  40
Iowa Hawkeyes

Nov 15, 2025 - NCAA

USC Trojans
26 :  21
Iowa Hawkeyes

Oct 11, 2025 - NCAA

Wisconsin Badgers
0 :  37
Iowa Hawkeyes

Sep 19, 2025 - NCAA

Rutgers Scarlet Knights
28 :  38
Iowa Hawkeyes
Ohio State Buckeyes
Ohio State Buckeyes Latest matches
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 26, 2026 - NCAA

Ohio State Buckeyes
42 :  19
Illinois Fighting Illini

Sep 19, 2026 - NCAA

Ohio State Buckeyes
59 :  3
Kent State Golden Flashes

Sep 12, 2026 - NCAA

Texas Longhorns
24 :  23
Ohio State Buckeyes

Sep 5, 2026 - NCAA

Ohio State Buckeyes
56 :  3
Ball State Cardinals

Dec 31, 2025 - NCAA

Ohio State Buckeyes
14 :  24
Miami Hurricanes

Dec 6, 2025 - NCAA

Ohio State Buckeyes
10 :  13
Indiana Hoosiers
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 26, 2026 - NCAA

Ohio State Buckeyes
42 :  19
Illinois Fighting Illini

Sep 19, 2026 - NCAA

Ohio State Buckeyes
59 :  3
Kent State Golden Flashes

Sep 5, 2026 - NCAA

Ohio State Buckeyes
56 :  3
Ball State Cardinals

Dec 31, 2025 - NCAA

Ohio State Buckeyes
14 :  24
Miami Hurricanes

Dec 6, 2025 - NCAA

Ohio State Buckeyes
10 :  13
Indiana Hoosiers

Nov 22, 2025 - NCAA

Ohio State Buckeyes
42 :  9
Rutgers Scarlet Knights
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 12, 2026 - NCAA

Texas Longhorns
24 :  23
Ohio State Buckeyes

Nov 29, 2025 - NCAA

Michigan Wolverines
9 :  27
Ohio State Buckeyes

Nov 8, 2025 - NCAA

Purdue Boilermakers
10 :  34
Ohio State Buckeyes

Oct 18, 2025 - NCAA

Wisconsin Badgers
0 :  34
Ohio State Buckeyes

Oct 11, 2025 - NCAA

Illinois Fighting Illini
16 :  34
Ohio State Buckeyes

Jan 10, 2025 - NCAA

Texas Longhorns
14 :  28
Ohio State Buckeyes
Iowa Hawkeyes vs Ohio State Buckeyes Picks

Iowa Hawkeyes - Ohio State Buckeyes Key Points

  1. The Over is 4-0 for Ohio State this season
  2. Ohio State is averaging 45.0 points per game this season
  3. The Over is 1-3 for Iowa this season
  4. Iowa is averaging 32.8 points per game this season

Our Iowa Hawkeyes vs Ohio State Buckeyes Prediction

Ohio State is the two-touchdown favorite in this game; however, the over looks to be the best betting option. For one, Ohio State has seen all of their games this season go over the total that we have for this game. Further, the Buckeyes are averaging 45.0 points per game. Iowa, on the other hand, is averaging 32.8 points per game this season, but has seen the total go over in just one of their four games. 

It is hard to believe that this game will be back and forth, with Ohio State likely to be the one that carries the scoring. That said, the Buckeyes’ defense is not unstoppable; therefore, our Ohio State Buckeyes vs. Iowa Hawkeyes prediction is: Over 45.5 Total Points.

Prediction:

 

Over 45.5 Total Points

-110
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.