Mazatlan FC vs Club Santos Laguna Prediction & Picks - Liga MX

Mexico - Liga MX

Mazatlan FC
10/21/25 23:00
Club Santos Laguna

Prediction:

 

Santos Laguna Total Goals - Over 1.5

+175
$500+ offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Edgar Jibran | in Liga MX Picks

Liga MX Matchday 14 is expected to bring many attractive games for the soccer fans in Mexico and the US; however, the clash between Mazatlan and Santos Laguna will practically be ignored by everybody, as it features two of the weakest teams in the league. However, this game could be one of the season's most important for both teams due to their closeness to play-in spots.

Considering this context, both teams must deliver their best efforts to secure a victory that would keep them in competition for the last rounds of the regular season, it being worth noting that the bookmakers’ odds have made Mazatlan favorites to win. Most of that favoritism is based on the fact that they have only lost to Pumas UNAM when playing at home this season, so this team is expected to maintain the offensive consistency shown throughout the season

As for Santos Laguna, this team has depended on playing at home to get positive results in the current season, but playing on the road has been such a nightmare. Most of this situation is based on their terrible defensive performance when playing away from home, regardless of their games being played at Mexico City altitude or very close to their hometown.

Up to $500+ to bet on Mazatlan FC - Club Santos Laguna! 

Limited Offer. Currently at Caesars Sportsbook

Mazatlan FC vs Club Santos Laguna Form

Table

Teams Pts P W D L GD
11
Club Santos Laguna
Club Santos Laguna
14 14 4 2 8 -6
14
Mazatlan FC
Mazatlan FC
12 14 2 6 6 -8

Mazatlan FC and Club Santos Laguna Latest Matches

Mazatlan FC
Mazatlan FC Latest matches
L D D L W L
Victories

1/6 (17%)

Draw

2/6 (33%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

3.33 Total goals
83% BTTS
1.17 Goals scored
2.17 Goals conceded
67% Over 2.5
33% Under 2.5

Oct 18, 2025 - Liga MX

Chivas
2 :  0
Mazatlan FC

Oct 3, 2025 - Liga MX

Mazatlan FC
2 :  1
Atletico San Luis

Sep 27, 2025 - Liga MX

Deportivo Toluca FC
3 :  1
Mazatlan FC

Sep 23, 2025 - Liga MX

Club Leon
2 :  2
Mazatlan FC

Sep 19, 2025 - Liga MX

Mazatlan FC
1 :  1
Atlas FC

Sep 12, 2025 - Liga MX

Mazatlan FC
1 :  4
Pumas UNAM
L D D L D W
Victories

1/6 (17%)

Draw

3/6 (50%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

3.33 Total goals
83% BTTS
1.33 Goals scored
2 Goals conceded
67% Over 2.5
33% Under 2.5

Oct 3, 2025 - Liga MX

Mazatlan FC
2 :  1
Atletico San Luis

Sep 19, 2025 - Liga MX

Mazatlan FC
1 :  1
Atlas FC

Sep 12, 2025 - Liga MX

Mazatlan FC
1 :  4
Pumas UNAM

Aug 23, 2025 - Liga MX

Mazatlan FC
2 :  2
Tigres UANL

Aug 9, 2025 - Liga MX

Mazatlan FC
2 :  2
Tijuana

Aug 5, 2025 - Leagues Cup

Mazatlan FC
0 :  2
San Diego FC
W L L D L L
Victories

1/6 (17%)

Draw

1/6 (17%)

Defeats

4/6 (67%)

Average stats (Last 6 matchs)

3 Total goals
50% BTTS
1.17 Goals scored
1.83 Goals conceded
50% Over 2.5
50% Under 2.5

Oct 18, 2025 - Liga MX

Chivas
2 :  0
Mazatlan FC

Sep 27, 2025 - Liga MX

Deportivo Toluca FC
3 :  1
Mazatlan FC

Sep 23, 2025 - Liga MX

Club Leon
2 :  2
Mazatlan FC

Aug 29, 2025 - Liga MX

FC Juarez
1 :  0
Mazatlan FC

Aug 17, 2025 - Liga MX

Monterrey
3 :  2
Mazatlan FC

Aug 1, 2025 - Leagues Cup

Houston Dynamo
0 :  2
Mazatlan FC
Club Santos Laguna
Club Santos Laguna Latest matches
D L W L L W
Victories

2/6 (33%)

Draw

1/6 (17%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

2.67 Total goals
33% BTTS
1 Goals scored
1.67 Goals conceded
50% Over 2.5
50% Under 2.5

Oct 18, 2025 - Liga MX

Club Santos Laguna
2 :  0
Club Leon

Oct 4, 2025 - Liga MX

CF America
3 :  0
Club Santos Laguna

Sep 27, 2025 - Liga MX

Monterrey
1 :  0
Club Santos Laguna

Sep 24, 2025 - Liga MX

Club Santos Laguna
1 :  0
Tijuana

Sep 21, 2025 - Liga MX

Club Santos Laguna
1 :  4
Atletico San Luis

Sep 13, 2025 - Liga MX

Atlas FC
2 :  2
Club Santos Laguna
L W L L W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

2.67 Total goals
33% BTTS
1.17 Goals scored
1.5 Goals conceded
33% Over 2.5
67% Under 2.5

Oct 18, 2025 - Liga MX

Club Santos Laguna
2 :  0
Club Leon

Sep 24, 2025 - Liga MX

Club Santos Laguna
1 :  0
Tijuana

Sep 21, 2025 - Liga MX

Club Santos Laguna
1 :  4
Atletico San Luis

Aug 30, 2025 - Liga MX

Club Santos Laguna
0 :  1
Tigres UANL

Aug 10, 2025 - Liga MX

Club Santos Laguna
1 :  0
Chivas

Jul 16, 2025 - Liga MX

Club Santos Laguna
2 :  4
Deportivo Toluca FC
L L L D L L
Victories

0/6 (0%)

Draw

1/6 (17%)

Defeats

5/6 (83%)

Average stats (Last 6 matchs)

3.33 Total goals
50% BTTS
0.83 Goals scored
2.5 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 4, 2025 - Liga MX

CF America
3 :  0
Club Santos Laguna

Sep 27, 2025 - Liga MX

Monterrey
1 :  0
Club Santos Laguna

Sep 13, 2025 - Liga MX

Atlas FC
2 :  2
Club Santos Laguna

Aug 22, 2025 - Liga MX

FC Juarez
2 :  1
Club Santos Laguna

Aug 16, 2025 - Liga MX

CF Cruz Azul
3 :  2
Club Santos Laguna

Aug 7, 2025 - Leagues Cup

Los Angeles Galaxy
4 :  0
Club Santos Laguna

Mazatlan FC against Club Santos Laguna : Head to Head (H2H)

Mazatlan FC

17 %

Draw

33 %

Club Santos Laguna

50 %

Average stats (last H2H results)

2.17
Total goals
67%
BTTS
1
Goals scored (Team 1)
1.17
Goals scored (Team 2)
50%
Over 2.5
50%
Under 2.5

Feb 14, 2025 - Liga MX

Mazatlan FC
1 :  1
Club Santos Laguna

Oct 25, 2024 - Liga MX

Club Santos Laguna
0 :  0
Mazatlan FC

Feb 25, 2024 - Liga MX

Club Santos Laguna
1 :  0
Mazatlan FC

Nov 23, 2023 - Liga MX

Club Santos Laguna
2 :  1
Mazatlan FC

Nov 1, 2023 - Liga MX

Mazatlan FC
3 :  1
Club Santos Laguna

Jan 20, 2023 - Liga MX

Mazatlan FC
1 :  2
Club Santos Laguna
Improve your sports betting with our football team comparison tool (100+ statistics)

Mazatlan FC against Club Santos Laguna Lineups: Starting 11

Mazatlan FC

Formation : 3 - 4 - 3

1
R. Gutierrez
15
B. Colula
5
F. Almada
26
A. Leyva
4
J. Diaz
16
J. Esquivel
6
R. Meraz
9
A. Duarte
28
D. Hernandez
90
Fabio
20
M. Lainez
7
C. Dajome
11
C. Lozano
6
J. Guemez
5
A. Lopez
26
R. Sordo
8
S. Mariscal
2
B. Amione
35
K. Balanta
19
H. Ortega
4
J. Abella
1
C. Acevedo

Formation : 4 - 1 - 4 - 1

Club Santos Laguna

Missing players

Mazatlan FC
Mazatlan FC
Forward

O. Moreno

Club Santos Laguna
Club Santos Laguna
Forward

F. Fagundez

Most goals and assists

CD Huachipato Mazatlan FC
CD Huachipato Club Santos Laguna
Top Goalscorer
Colombia N. Benedetti (7 Goals)
Top Goalscorer
Chile B. Barticciotto (8 Goals)
Best assists
Colombia N. Benedetti (5 Assists)
Best assists
Mexico J. Abella (4 Assists)
Spain F. Villalba (4 Assists)

Mazatlan FC - Club Santos Laguna Key Points

  1. Mazatlan has consistently scored at least one goal when playing at home in their last six Liga MX games.
  2. Santos Laguna has a more than twenty-game road winless streak, numbers that reflect the deep issues that the whole franchise has been recently experiencing.
  3. Mazatlan has scored at least one goal during their last five home meetings with Santos Laguna.
  4. Santos Laguna has also consistently scored at least one goal when facing Mazatlan on the road since December 2022.
Up to $500+ to bet on Mazatlan FC - Club Santos Laguna! 

Limited Offer. Currently at Caesars Sportsbook

Our Mazatlan FC vs Club Santos Laguna Prediction

Despite featuring two of the least attractive Liga MX teams, it must be noted that they have consistently offered very attractive matchups between them, so for this new confrontation, both are expected to maintain that offensive trend by creating dangerous opportunities throughout the entire game.

In summary, despite the bookmakers’ odds making Mazatlan favorites, the reality is that Santos Laguna is currently closer to the Play-In spots, so they’re expected to play this game at their highest possible level to keep pace with Pumas UNAM in the standings. Therefore, the pick for Mazatlan FC – Club Santos Laguna is: Santos Laguna Total Goals – Over 1.5!

Prediction:

 

Santos Laguna Total Goals - Over 1.5

+175
$500+ offered for betting!

Right now, claim $500+ for your Mazatlan FC vs Club Santos Laguna wager!

Get 20 Double Winnings Tokens!

Caesars Sportsbook is offering an extraordinary opportunity for new bettors to unlock 20 'double your winnings' tokens, for a total of $500+! You can access this promo for the Mazatlan FC vs Club Santos Laguna matchup! 

New users can access the bonus on Caesars Sportsbook Mobile or through the website by creating an account during the promotion period and registering using a special promo code. This offer is a chance for newcomers to experience the thrill of sports betting with a significant boost, courtesy of Caesars Sportsbook.

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Mazatlan FC vs Club Santos Laguna Picks