Ole Miss Rebels vs LSU Tigers Prediction & Picks - NCAA
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by Matt Lowrimore | in NCAA Picks
The biggest game of the Week 3 Saturday College Football slate will see the LSU Tigers take on the Ole Miss Rebels. Let’s take a look at the match statistics and predictions for this game between the Tigers and the Rebels.
LSU enters this game with a record of 2-0 and is ranked #7 in the top-25 poll. Further, this will be the first SEC game for the Tigers and it will be the first time that head coach Lane Kiffin returns to Ole Miss to take on his former team.
LSU beat Louisiana Tech in Week 2 by a score of 45-14, but it took until the second half for them to pull away, and it was despite their quarterback throwing four interceptions. Facing a hostile crowd in Oxford could lead to more mistakes by the Tigers, suggesting the Rebels will be able to gain momentum early.
As for Ole Miss, they also enter this game with a record of 2-0 and are ranked #8 in the top-25 poll. The Rebels are coming off a dominant 41-9 win over Charlotte in Week 2, a game they were never in doubt of losing. Ole Miss does already have a top-25 win this season, against Louisville in Week 1, which shows they can grind a win out when they need to.
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Ole Miss Rebels vs LSU Tigers Form
Table
Ole Miss Rebels and LSU Tigers Latest Matches
5/6 (83%)
1/6 (17%)
Sep 12, 2026 - NCAA
Sep 6, 2026 - NCAA
Jan 8, 2026 - NCAA
Jan 1, 2026 - NCAA
Dec 20, 2025 - NCAA
Nov 28, 2025 - NCAA
5/6 (83%)
1/6 (17%)
Sep 12, 2026 - NCAA
Sep 6, 2026 - NCAA
Jan 8, 2026 - NCAA
Dec 20, 2025 - NCAA
Nov 15, 2025 - NCAA
Nov 8, 2025 - NCAA
4/5 (80%)
1/5 (20%)
Jan 1, 2026 - NCAA
Nov 28, 2025 - NCAA
Oct 25, 2025 - NCAA
Oct 18, 2025 - NCAA
Sep 6, 2025 - NCAA
4/6 (67%)
2/6 (33%)
Sep 12, 2026 - NCAA
Sep 5, 2026 - NCAA
Dec 27, 2025 - NCAA Division I, FBS, Playoffs
Nov 29, 2025 - NCAA
Nov 22, 2025 - NCAA
Nov 15, 2025 - NCAA
5/6 (83%)
1/6 (17%)
Sep 12, 2026 - NCAA
Sep 5, 2026 - NCAA
Nov 22, 2025 - NCAA
Nov 15, 2025 - NCAA
Oct 25, 2025 - NCAA
Oct 11, 2025 - NCAA
1/6 (17%)
5/6 (83%)
Dec 27, 2025 - NCAA Division I, FBS, Playoffs
Nov 29, 2025 - NCAA
Nov 8, 2025 - NCAA
Oct 18, 2025 - NCAA
Sep 27, 2025 - NCAA
Aug 30, 2025 - NCAA
Ole Miss Rebels against LSU Tigers : Head to Head (H2H)
100 %
0 %
Sep 27, 2025 - NCAA
Ole Miss Rebels - LSU Tigers Key Points
- LSU is averaging 48 points per game this season
- LSU is allowing 12 points per game this season
- Ole Miss is averaging 41 points per game this season
- Ole Miss is allowing 23.5 points per game this season
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Our Ole Miss Rebels vs LSU Tigers Prediction
LSU is the small favorite in this game; however, Ole Miss looks to be the best betting option. A big part of this is because of the environment that LSU is set to face. The crowd is likely going to be much more hostile than usual, which looks likely to affect the Tigers in a negative way. Especially the LSU quarterback, Sam Leavitt, who threw four interceptions against Louisiana Tech at home last week.
Both offenses have been more than efficient this season, and while LSU has overall been the better defense, they have not played on the road this season against a quality team. For that reason, our LSU Tigers vs. Ole Miss Rebels prediction is: Ole Miss Rebels +3.5 Alternate Spread.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
