Karen Khachanov vs Dino Prizmic Prediction & Picks - ATP Italian Open

Prediction published on 5/12/26, 1:07 AM  by Lou Aguila | Modified on 5/12/26 at 11:46 PM in ATP Italian Open Picks

Despite catching a steep price of -190 on the moneyline, Dino Prizmic remains a compelling on the spread at -120 to cover -2.5 games against Karen Khachanov in the fourth round of the 2026 Rome Masters.

Current Form:

Karen Khachanov advanced to the round of 16 in Rome after coming back from a set down to defeat Botic Van De Zandschulp 5-7, 6-4, 6-4. The clay-court swing didn’t go as planned for Khachanov, who lost both his opening matches in Monte Carlo and Barcelona and picked up just one win in Madrid before getting the boot from Jakub Mensik in the third round.

Khachanov, who also swept Alexander Shevchenko 6-4, 6-4 in the second round, came out of the gates as a +140 underdog against one of the hottest players in Rome – Dino Prizmic.

Prizmic has extended his winning streak to five matches after coming through with a sublime straight-set win over Ugo Humbert 6-1, 7-5. Prizmic, a qualifier at this ATP 1000 event in Rome, carried over the momentum from his shocking upset of Novak Djokovic 2-6, 6-2, 6-4 in the second round. Ranked 79th in the world, the Croatian youngster enhanced his 2026 clay-court record to 19-15.

Sportsbook is apparently buying the hype around the 20-year-old Prizmic, who commands a -190 price ahead of his first match against a top-15 player on the ATP Tour. The sportsbook is anticipating a drawn-out battle from this matchup after pegging the over/under at 22.5 games.