Indiana Hoosiers vs Oregon Ducks Prediction & Picks - NCAA

USA - NCAA

Indiana Hoosiers
10/11/25 15:30
Oregon Ducks

Prediction:

 

Indiana Hoosiers +7.5

-115
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 by Matt Lowrimore in NCAA Picks

Another one of the huge matchups on the Week 7 Saturday college football slate will feature the 7th-ranked Indiana Hoosiers and the 3rd-ranked Oregon Ducks. Let’s take a look at the match statistics and predictions for this game between the Hoosiers and the Ducks.

Indiana enters this game with a record of 5-0 and 2-0 in the Big Ten. The Hoosiers most recently beat the Iowa Hawkeyes in Week 5 by a score of 20-15. Indiana’s offense had a total of 337 yards. Quarterback Fernando Mendoza threw for 233 yards, two touchdowns, and one interception, while running back Roman Hemby led the team in rushing with 86 yards. 

As for Oregon, they also enter this game with a record of 5-0 and 2-0 in the Big Ten. The Ducks most recently beat the Penn State Nittany Lions in Week 5 by a score of 30-24 in overtime. Oregon’s offense had a total of 424 yards, while its defense allowed 276 yards. Quarterback Dante Moore threw for 248 yards and three touchdowns, while running back Dierre Hill Jr. led the team in rushing with 82 yards.

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Indiana Hoosiers vs Oregon Ducks Form

Table

Teams % P W D L
2
Indiana Hoosiers
Indiana Hoosiers
1 2 2 0 0
4
Oregon Ducks
Oregon Ducks
1 2 2 0 0

Indiana Hoosiers and Oregon Ducks Latest Matches

Indiana Hoosiers
Indiana Hoosiers Latest matches
L W W W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Sep 27, 2025 - NCAA

Indiana Hoosiers
20 :  15
Iowa Hawkeyes

Sep 20, 2025 - NCAA

Illinois Fighting Illini
10 :  63
Indiana Hoosiers

Sep 12, 2025 - NCAA

Indiana State Sycamores
0 :  73
Indiana Hoosiers

Sep 6, 2025 - NCAA

Kennesaw State Owls
9 :  56
Indiana Hoosiers

Aug 30, 2025 - NCAA

Old Dominion Monarchs
14 :  27
Indiana Hoosiers

Dec 20, 2024 - NCAA

Indiana Hoosiers
17 :  27
Notre Dame Fighting Irish
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Sep 20, 2025 - NCAA

Illinois Fighting Illini
10 :  63
Indiana Hoosiers

Sep 12, 2025 - NCAA

Indiana State Sycamores
0 :  73
Indiana Hoosiers

Sep 6, 2025 - NCAA

Kennesaw State Owls
9 :  56
Indiana Hoosiers

Aug 30, 2025 - NCAA

Old Dominion Monarchs
14 :  27
Indiana Hoosiers

Nov 30, 2024 - NCAA

Purdue Boilermakers
0 :  66
Indiana Hoosiers

Nov 9, 2024 - NCAA

Michigan Wolverines
15 :  20
Indiana Hoosiers
W W L L W
Victories

2/4 (50%)

Draw

0/4 (0%)

Defeats

2/4 (50%)

Sep 27, 2025 - NCAA

Indiana Hoosiers
20 :  15
Iowa Hawkeyes

Dec 20, 2024 - NCAA

Indiana Hoosiers
17 :  27
Notre Dame Fighting Irish

Nov 23, 2024 - NCAA

Indiana Hoosiers
15 :  38
Ohio State Buckeyes

Nov 2, 2024 - NCAA

Indiana Hoosiers
47 :  10
Michigan State Spartans
Oregon Ducks
Oregon Ducks Latest matches
L W W W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Sep 27, 2025 - NCAA

Oregon Ducks
30 :  24
Penn State Nittany Lions

Sep 20, 2025 - NCAA

Oregon State Beavers
7 :  41
Oregon Ducks

Sep 13, 2025 - NCAA

Oregon Ducks
34 :  14
Northwestern Wildcats

Sep 6, 2025 - NCAA

Oklahoma State Cowboys
3 :  69
Oregon Ducks

Aug 30, 2025 - NCAA

Montana State Bobcats
13 :  59
Oregon Ducks

Jan 1, 2025 - NCAA

Ohio State Buckeyes
41 :  21
Oregon Ducks
W W L W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Sep 20, 2025 - NCAA

Oregon State Beavers
7 :  41
Oregon Ducks

Sep 6, 2025 - NCAA

Oklahoma State Cowboys
3 :  69
Oregon Ducks

Aug 30, 2025 - NCAA

Montana State Bobcats
13 :  59
Oregon Ducks

Jan 1, 2025 - NCAA

Ohio State Buckeyes
41 :  21
Oregon Ducks

Dec 7, 2024 - NCAA

Penn State Nittany Lions
37 :  45
Oregon Ducks

Nov 30, 2024 - NCAA

Washington Huskies
21 :  49
Oregon Ducks
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Sep 27, 2025 - NCAA

Oregon Ducks
30 :  24
Penn State Nittany Lions

Sep 13, 2025 - NCAA

Oregon Ducks
34 :  14
Northwestern Wildcats

Nov 16, 2024 - NCAA

Oregon Ducks
16 :  13
Wisconsin Badgers

Nov 2, 2024 - NCAA

Oregon Ducks
38 :  17
Michigan Wolverines

Oct 18, 2024 - NCAA

Oregon Ducks
35 :  0
Purdue Boilermakers

Sep 28, 2024 - NCAA

Oregon Ducks
34 :  13
UCLA Bruins

Indiana Hoosiers - Oregon Ducks Key Points

  1. Oregon is 1-1 ATS vs the Big Ten
  2. Oregon is averaging 32.0 points per game vs the Big Ten
  3. Indiana is 1-1 ATS vs the Big Ten
  4. Indiana is averaging 41.5 points per game vs the Big Ten
Up to $200 to bet on Indiana Hoosiers - Oregon Ducks! 

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Our Indiana Hoosiers vs Oregon Ducks Prediction

Oregon is about a touchdown favorite in this matchup, but Indiana looks to be the better betting option. The Hoosiers have had an explosive offense all season, averaging 47.8 points per game overall. So even though Oregon is also undefeated, the Ducks have not always been efficient and have had some slow starts this season.

This game being in Oregon certainly gives the Ducks an advantage, but Indiana’s offense has been too strong to suggest that they cannot keep this game within a touchdown. Ultimately, an Oregon win is the most likely result; however, our Indiana Hoosiers vs Oregon Ducks prediction is: Indiana Hoosiers +7.5.

Prediction:

 

Indiana Hoosiers +7.5

-115
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Indiana Hoosiers vs Oregon Ducks Picks
Up to $200 to bet on Indiana Hoosiers - Oregon Ducks! 

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