Green Bay Packers vs Arizona Cardinals Prediction & Picks - NFL

USA - NFL

Green Bay Packers
10/19/25 16:25
Arizona Cardinals

Prediction:

 

Arizona +6.5

-105
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 by Bill Christy in NFL Picks

The banged-up Arizona Cardinals (2-4) will play hosts to the Green Bay Packers (3-1-1) late Sunday afternoon. The Cardinals fell just short of defeating he Indianapolis Colts last week with Jacoby Brissett starting in place of the injured Kyler Murray who could be out once again this week. The job was tough when Marvin Harrison Jr went down with a concussion midway through the game. All this coming after they lost star running back James Conner earlier this year for the season. While the 2-4 record is not great, it should be noted that these 4 losses have come by a combined 9 points. It is not like the Cardinals are laying down, they are just losing close games. The Packers, on the other hand, have won all 3 of their games by a decided margin of 10.6 points. Josh Jacobs has been running with purpose all season and Jordan Love has shown signs of being back to an elite passer. Jacobs has been dealing with an illness this week so that is something to keep an eye on as this game comes closer to kickoff. The defense is ranked in the top 10 in points allowed on the season and Micah Parsons has been a welcomed addition accounting for 2.4 sacks already this year in a limited capacity early.

Green Bay Packers vs Arizona Cardinals Form

Table

Teams % P W D L
3
Green Bay Packers
Green Bay Packers
0.6 5 3 1 1
26
Arizona Cardinals
Arizona Cardinals
0.333 6 2 0 4

Green Bay Packers and Arizona Cardinals Latest Matches

Green Bay Packers
Green Bay Packers Latest matches
L W W L D W
Victories

3/6 (50%)

Draw

1/6 (17%)

Defeats

2/6 (33%)

Oct 12, 2025 - NFL

Cincinnati Bengals
18 :  27
Green Bay Packers

Sep 28, 2025 - NFL

Green Bay Packers
40 :  40
Dallas Cowboys

Sep 21, 2025 - NFL

Green Bay Packers
10 :  13
Cleveland Browns

Sep 11, 2025 - NFL

Washington Commanders
18 :  27
Green Bay Packers

Sep 7, 2025 - NFL

Detroit Lions
13 :  27
Green Bay Packers

Jan 12, 2025 - NFL

Green Bay Packers
10 :  22
Philadelphia Eagles
W W L W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Oct 12, 2025 - NFL

Cincinnati Bengals
18 :  27
Green Bay Packers

Sep 11, 2025 - NFL

Washington Commanders
18 :  27
Green Bay Packers

Sep 7, 2025 - NFL

Detroit Lions
13 :  27
Green Bay Packers

Jan 5, 2025 - NFL

Chicago Bears
24 :  22
Green Bay Packers

Dec 23, 2024 - NFL

New Orleans Saints
0 :  34
Green Bay Packers

Nov 28, 2024 - NFL

Miami Dolphins
17 :  30
Green Bay Packers
L W L L L D
Victories

1/6 (17%)

Draw

1/6 (17%)

Defeats

4/6 (67%)

Sep 28, 2025 - NFL

Green Bay Packers
40 :  40
Dallas Cowboys

Sep 21, 2025 - NFL

Green Bay Packers
10 :  13
Cleveland Browns

Jan 12, 2025 - NFL

Green Bay Packers
10 :  22
Philadelphia Eagles

Dec 29, 2024 - NFL

Green Bay Packers
25 :  27
Minnesota Vikings

Dec 15, 2024 - NFL

Green Bay Packers
30 :  13
Seattle Seahawks

Dec 5, 2024 - NFL

Green Bay Packers
31 :  34
Detroit Lions
Arizona Cardinals
Arizona Cardinals Latest matches
W W L L L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts

Oct 5, 2025 - NFL

Tennessee Titans
22 :  21
Arizona Cardinals

Sep 25, 2025 - NFL

Seattle Seahawks
23 :  20
Arizona Cardinals

Sep 21, 2025 - NFL

Arizona Cardinals
15 :  16
San Francisco 49ers

Sep 14, 2025 - NFL

Carolina Panthers
22 :  27
Arizona Cardinals

Sep 7, 2025 - NFL

Arizona Cardinals
20 :  13
New Orleans Saints
L W W W L L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Oct 5, 2025 - NFL

Tennessee Titans
22 :  21
Arizona Cardinals

Sep 25, 2025 - NFL

Seattle Seahawks
23 :  20
Arizona Cardinals

Sep 14, 2025 - NFL

Carolina Panthers
22 :  27
Arizona Cardinals

Jan 5, 2025 - NFL

San Francisco 49ers
24 :  47
Arizona Cardinals

Dec 15, 2024 - NFL

New England Patriots
17 :  30
Arizona Cardinals

Dec 8, 2024 - NFL

Seattle Seahawks
30 :  18
Arizona Cardinals
L L L W L L
Victories

1/6 (17%)

Draw

0/6 (0%)

Defeats

5/6 (83%)

Oct 12, 2025 - NFL

Arizona Cardinals
27 :  31
Indianapolis Colts

Sep 21, 2025 - NFL

Arizona Cardinals
15 :  16
San Francisco 49ers

Sep 7, 2025 - NFL

Arizona Cardinals
20 :  13
New Orleans Saints

Dec 28, 2024 - NFL

Arizona Cardinals
9 :  13
Los Angeles Rams

Dec 22, 2024 - NFL

Arizona Cardinals
30 :  36
Carolina Panthers

Dec 1, 2024 - NFL

Arizona Cardinals
22 :  23
Minnesota Vikings

Green Bay Packers against Arizona Cardinals : Head to Head (H2H)

Oct 13, 2024 - NFL

Arizona Cardinals
13 :  34
Green Bay Packers

Green Bay Packers - Arizona Cardinals Key Points

  1. Arizona is 7-1 ATS in its last 8 games when playing as the underdog.
  2. Arizona is 5-1 ATS in its last 6 games played in week 7.
  3. Green Bay is 2-6 ATS in its last 8 games.
  4. Green Bay is 1-4 ATS in its last 5 games on the road.

Our Green Bay Packers vs Arizona Cardinals Prediction

While the Packers were able to put the Bengals away last week, the game was much closer than the final score indicates. They also tied with a Cowboys team that seemingly always finds a way to lose and their only loss of the season came to the lowly Browns. This Packer team seems to play to the level of their competition and the Cardinals find a way to keep these games close. That is why we are backing the home underdogs in this one.

Prediction:

 

Arizona +6.5

-105
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Green Bay Packers vs Arizona Cardinals Picks