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by Lou Aguila in NFL Picks
The Indianapolis Colts and the Denver Broncos clash heads in Week 2 of the NFL season on Sunday at Lucas Oil Stadium.
The Colts are coming in as home underdogs at +110 despite coming off a dominant win over the Miami Dolphins 33-8 in the series opener.
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The Colts opened their season on an emphatic note, crushing the Dolphins by 25 points in week 1. Daniel Jones dazzled in his Colts debut as the quarterback completed 22 of his 29 passes for 272 yards and one TD while rushing for two more touchdowns. Indianapolis showcased its defensive might against Miami, holding the Dolphins to 133 passing yards and 78 rushing yards. They forced Miami quarterback Tua Tagovailoa to complete only 14 of his 23 passes and throw two interceptions.
The Broncos also won their first assignment, thanks to their formidable defense. Denver allowed only 133 total yards in this match while making every play difficult for 2025 No.1 overall pick Cam Ward, who finished with 112 passing yards on a 42.9% completion percentage and zero touchdowns. Denver quarterback Bo Nix threw for 176 yards with one TD, but he completed only 62 percent of his passes and recorded two interceptions. Trailing by 12-10 early in the third quarter, Denver scored the final 10 points of the game with JK Dobbins converting on a 19-yard rushing TD and Wil Lutz scoring on two field-goal attempts.
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Denver Broncos vs Indianapolis Colts Form
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Denver Broncos and Indianapolis Colts Latest Matches
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Denver Broncos against Indianapolis Colts : Head to Head (H2H)
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Denver Broncos - Indianapolis Colts Key Points
- Indianapolis is 7-1 SU in its last 8 games when playing at home against Denver.
- Indianapolis is 6-2 SU in its last 8 games at home.
- Denver is 6-3 SU in its last 9 games.
- Denver is 1-5 SU in its last 6 games on the road.
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Our Denver Broncos vs Indianapolis Colts Prediction
This looks like another thrilling matchup between two really good defensive teams, but I am going with the Colts in this one. Not only because they are playing at Lucas Oil Stadium, where they are 6-2 in their last 8 games, but Indianapolis is 7-1 SU in its last 8 games against Denver at the stadium. Moreover, I like what I saw from Daniel Jones in his first game with the Colts. Protected by a terrific offensive line, Jones played like an elite-level quarterback out there, slicing and dicing Miami’s defense like they were made of thin paper. I expect Jones to continue delivering the goods for as long as the O-Line does its job.
Bo Nix had a so-so opening week performance against the Titans. It would be interesting to see how he can elevate his play against a Colts defense that plays as ferocious as Denver’s defensive unit. There’s a high possibility this will turn into a physical battle, given the defensive prowess both teams possess. Regardless, the Colts appear to be an intriguing underdog pick because of their head-to-head superiority in their recent games and the promising play of their new quarterback.
Our betting prediction for the Denver Broncos vs. the Indianapolis Colts: the Colts will win.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
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