Chicago Blackhawks vs Buffalo Sabres Prediction & Picks - NHL

USA - NHL

Chicago Blackhawks
11/21/25 19:00
Buffalo Sabres

Prediction:

 

Blackhawks to win

+155
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 by Taavi Pailk in NHL Picks

In an NHL inter-conference matchup, the Buffalo Sabres welcome the Chicago Blackhawks to the KeyBank Center on Friday.

The Sabres enter the action as the last-placed team in the Eastern Conference. Lindy Ruff's men hold the fifth-worst defensive record in the NHL, and the offense hasn't been good enough to deliver the team victories on a consistent basis.

On Wednesday, the Sabres were unable to record their first three-game winning streak of the season, suffering a 6-2 home loss to the Calgary Flames. The team erased a 2-0 deficit in the second period but allowed four goals in the final frame.

The Blackhawks beat the Flames on Tuesday to improve to 10-5-4. They enter Thursday's matchup against the Seattle Kraken with a 5-0-1 run over their last six contests. Playing on consecutive nights is always challenging for teams, but Jeff Blashill's squad currently has good momentum that should help them manage any fatigue.

Chicago has been very impressive this season, holding the fourth-best defensive record in the league and averaging the fifth-most goals. Their young star Connor Bedard has been exceptional lately, notching 10 goals and 11 assists over the past 10 games.

Chicago Blackhawks vs Buffalo Sabres Form

Table

Teams Pts P W L GD
5
Chicago Blackhawks
Chicago Blackhawks
24 19 10 9 15
16
Buffalo Sabres
Buffalo Sabres
18 20 7 13 -13

Chicago Blackhawks and Buffalo Sabres Latest Matches

Chicago Blackhawks
Chicago Blackhawks Latest matches
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Nov 18, 2025 - NHL

Calgary Flames
2 :  5
Chicago Blackhawks

Nov 15, 2025 - NHL

Toronto Maple Leafs
2 :  3
Chicago Blackhawks

Nov 12, 2025 - NHL

New Jersey Devils
4 :  3
Chicago Blackhawks

Nov 9, 2025 - NHL

Chicago Blackhawks
5 :  1
Detroit Red Wings

Nov 7, 2025 - NHL

Chicago Blackhawks
4 :  0
Calgary Flames

Nov 5, 2025 - NHL

Chicago Blackhawks
5 :  2
Vancouver Canucks
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 18, 2025 - NHL

Calgary Flames
2 :  5
Chicago Blackhawks

Nov 15, 2025 - NHL

Toronto Maple Leafs
2 :  3
Chicago Blackhawks

Nov 12, 2025 - NHL

New Jersey Devils
4 :  3
Chicago Blackhawks

Oct 28, 2025 - NHL

Ottawa Senators
3 :  7
Chicago Blackhawks

Oct 26, 2025 - NHL

Los Angeles Kings
3 :  1
Chicago Blackhawks

Oct 19, 2025 - NHL

Anaheim Ducks
1 :  2
Chicago Blackhawks
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 9, 2025 - NHL

Chicago Blackhawks
5 :  1
Detroit Red Wings

Nov 7, 2025 - NHL

Chicago Blackhawks
4 :  0
Calgary Flames

Nov 5, 2025 - NHL

Chicago Blackhawks
5 :  2
Vancouver Canucks

Nov 3, 2025 - NHL

Chicago Blackhawks
1 :  3
Seattle Kraken

Nov 1, 2025 - NHL

Chicago Blackhawks
2 :  3
Edmonton Oilers

Oct 30, 2025 - NHL

Chicago Blackhawks
3 :  6
Winnipeg Jets
Buffalo Sabres
Buffalo Sabres Latest matches
L L L W W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 19, 2025 - NHL

Calgary Flames
6 :  2
Buffalo Sabres

Nov 17, 2025 - NHL

Edmonton Oilers
1 :  5
Buffalo Sabres

Nov 15, 2025 - NHL

Buffalo Sabres
5 :  4
Detroit Red Wings

Nov 13, 2025 - NHL

Buffalo Sabres
3 :  6
Colorado Avalanche

Nov 12, 2025 - NHL

Buffalo Sabres
2 :  5
Utah Mammoth

Nov 8, 2025 - NHL

Buffalo Sabres
3 :  6
Carolina Hurricanes
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Nov 19, 2025 - NHL

Calgary Flames
6 :  2
Buffalo Sabres

Nov 17, 2025 - NHL

Edmonton Oilers
1 :  5
Buffalo Sabres

Nov 6, 2025 - NHL

St. Louis Blues
3 :  0
Buffalo Sabres

Nov 4, 2025 - NHL

Utah Mammoth
2 :  1
Buffalo Sabres

Nov 1, 2025 - NHL

Washington Capitals
3 :  4
Buffalo Sabres

Oct 28, 2025 - NHL

Columbus Blue Jackets
4 :  3
Buffalo Sabres
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Nov 15, 2025 - NHL

Buffalo Sabres
5 :  4
Detroit Red Wings

Nov 13, 2025 - NHL

Buffalo Sabres
3 :  6
Colorado Avalanche

Nov 12, 2025 - NHL

Buffalo Sabres
2 :  5
Utah Mammoth

Nov 8, 2025 - NHL

Buffalo Sabres
3 :  6
Carolina Hurricanes

Oct 30, 2025 - NHL

Buffalo Sabres
3 :  4
Boston Bruins

Oct 25, 2025 - NHL

Buffalo Sabres
3 :  4
Toronto Maple Leafs

Chicago Blackhawks against Buffalo Sabres : Head to Head (H2H)

Chicago Blackhawks

50 %

Buffalo Sabres

50 %

Dec 27, 2024 - NHL

Chicago Blackhawks
2 :  6
Buffalo Sabres

Dec 8, 2017 - NHL

Buffalo Sabres
2 :  3
Chicago Blackhawks

Chicago Blackhawks - Buffalo Sabres Key Points

  1. Buffalo has beaten Chicago in four consecutive regular-season meetings.
  2. The Sabres have a 6-4-2 record at home this season.
  3. The Blackhawks have gone 5-3-2 on the road, winning each of their last three away games.
  4. Buffalo has killed off a league-best 89.9 percent of penalties, while Chicago is ranked at sixth at 84.3 percent.

Our Chicago Blackhawks vs Buffalo Sabres Prediction

The Sabres recently managed to defeat Detroit and Edmonton in back-to-back games, but the team is giving up a lot of goals, which makes it extremely difficult to climb out from the bottom of the Eastern Conference.

After opening the season with three consecutive losses, the Blackhawks have suffered only a handful of regulation defeats. They have played high-level hockey on both ends of the ice and look ready to end a five-year postseason drought. In contrast, Buffalo appears very far from breaking its run of 14 consecutive seasons without a playoff appearance.

Our prediction for Chicago Blackhawks vs. Buffalo Sabres: Blackhawks to win.

Prediction:

 

Blackhawks to win

+155
$150 offered for betting!

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Chicago Blackhawks vs Buffalo Sabres Picks