Buffalo Bills vs Atlanta Falcons Prediction & Picks - NFL

USA - NFL

Buffalo Bills
10/13/25 19:15
Atlanta Falcons

Prediction:

 

Bills -4.5

-110
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 by Travis Pulver in NFL Picks

The Buffalo Bills will try to get back on the right side of the scoreboard this week when they travel down to Georgia to play the Falcons at Mercedes-Benz Stadium in Atlanta. Kickoff for this AFC East-NFC South battle is scheduled for 7:15 p.m. EST on Monday Night Football.

Buffalo had been on cruise control prior to last week’s surprising loss to the New England Patriots. It was a sloppy game for the Bills with 11 penalties and three turnovers. They held the ball for over 34 minutes, but struggled to complete drives with touchdowns. The defense had been vulnerable against the run but held the Patriots to 71 yards on the ground. As for Atlanta, the Falcons have had issues with consistency on offense. It is actually the No. 7 unit in total yards, but they are only scoring 19 points a game (27th in the league). They have a similar issue on the defensive side of the ball. The unit is first in the league in total yards allowed (244 per game; 135 passing and 109 rushing), but they give up 21.5 points per game (15th in the league).

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Buffalo Bills vs Atlanta Falcons Form

Table

Teams % P W D L
4
Buffalo Bills
Buffalo Bills
0.8 5 4 0 1
17
Atlanta Falcons
Atlanta Falcons
0.5 4 2 0 2

Buffalo Bills and Atlanta Falcons Latest Matches

Buffalo Bills
Buffalo Bills Latest matches
L W W W W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Oct 5, 2025 - NFL

New England Patriots
23 :  20
Buffalo Bills

Sep 28, 2025 - NFL

New Orleans Saints
19 :  31
Buffalo Bills

Sep 18, 2025 - NFL

Miami Dolphins
21 :  31
Buffalo Bills

Sep 14, 2025 - NFL

Buffalo Bills
30 :  10
New York Jets

Sep 7, 2025 - NFL

Baltimore Ravens
40 :  41
Buffalo Bills

Jan 26, 2025 - NFL

Buffalo Bills
29 :  32
Kansas City Chiefs
W W W W W L
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Oct 5, 2025 - NFL

New England Patriots
23 :  20
Buffalo Bills

Sep 28, 2025 - NFL

New Orleans Saints
19 :  31
Buffalo Bills

Sep 18, 2025 - NFL

Miami Dolphins
21 :  31
Buffalo Bills

Sep 7, 2025 - NFL

Baltimore Ravens
40 :  41
Buffalo Bills

Jan 19, 2025 - NFL

Baltimore Ravens
25 :  27
Buffalo Bills

Jan 12, 2025 - NFL

Denver Broncos
7 :  31
Buffalo Bills
W L W L L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Sep 14, 2025 - NFL

Buffalo Bills
30 :  10
New York Jets

Jan 26, 2025 - NFL

Buffalo Bills
29 :  32
Kansas City Chiefs

Jan 5, 2025 - NFL

Buffalo Bills
16 :  23
New England Patriots

Dec 15, 2024 - NFL

Buffalo Bills
48 :  42
Detroit Lions

Dec 8, 2024 - NFL

Buffalo Bills
42 :  44
Los Angeles Rams

Nov 10, 2024 - NFL

Buffalo Bills
30 :  20
Indianapolis Colts
Atlanta Falcons
Atlanta Falcons Latest matches
L L L W L W
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Sep 28, 2025 - NFL

Washington Commanders
27 :  34
Atlanta Falcons

Sep 21, 2025 - NFL

Atlanta Falcons
0 :  30
Carolina Panthers

Sep 14, 2025 - NFL

Atlanta Falcons
22 :  6
Minnesota Vikings

Sep 7, 2025 - NFL

Tampa Bay Buccaneers
23 :  20
Atlanta Falcons

Jan 5, 2025 - NFL

Carolina Panthers
44 :  38
Atlanta Falcons

Dec 29, 2024 - NFL

Atlanta Falcons
24 :  30
Washington Commanders
W L W L L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Sep 28, 2025 - NFL

Washington Commanders
27 :  34
Atlanta Falcons

Sep 7, 2025 - NFL

Tampa Bay Buccaneers
23 :  20
Atlanta Falcons

Jan 5, 2025 - NFL

Carolina Panthers
44 :  38
Atlanta Falcons

Dec 22, 2024 - NFL

New York Giants
7 :  34
Atlanta Falcons

Dec 1, 2024 - NFL

Los Angeles Chargers
17 :  13
Atlanta Falcons

Nov 3, 2024 - NFL

Dallas Cowboys
21 :  27
Atlanta Falcons
L L W L W L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Sep 21, 2025 - NFL

Atlanta Falcons
0 :  30
Carolina Panthers

Sep 14, 2025 - NFL

Atlanta Falcons
22 :  6
Minnesota Vikings

Dec 29, 2024 - NFL

Atlanta Falcons
24 :  30
Washington Commanders

Dec 16, 2024 - NFL

Atlanta Falcons
15 :  9
Las Vegas Raiders

Dec 8, 2024 - NFL

Atlanta Falcons
21 :  42
Minnesota Vikings

Nov 17, 2024 - NFL

Atlanta Falcons
6 :  38
Denver Broncos

Buffalo Bills - Atlanta Falcons Key Points

  1. Atlanta leads the all-time series vs. Buffalo 7-6, but the Bills have won the last two.
  2. Atlanta is 3-1 when they have a rest advantage under Raheem Morris (since 2024).
  3. Buffalo is 15-10 under Sean McDermott when at a rest disadvantage (since 2017).
  4. Betting Public: 78% of spread tickets and 70% of the handle are on the Bills.
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Our Buffalo Bills vs Atlanta Falcons Prediction

Up until last week’s game against the Patriots, the Bills' defense had struggled against the run. With two solid running backs in Bijan Robinson and Tyler Allgeier, it would be smart for the Falcons to focus more on running rather than maintaining a balanced attack (49% run, 51% pass). But they seem determined to put the ball and the fate of the offense in the hands of Michael Penix Jr., who has just three touchdown passes after four games. Buffalo could easily get upset in this game if the offense comes out flat again and the Atlanta defense is half as good as it looks on paper. But I don’t think the Falcons' defense is as good as it seems, nor do I think the Bills' offense will come out flat. Buffalo will take care of business in this game.

Our Buffalo vs. Atlanta Pick: Bills -4.5

Prediction:

 

Bills -4.5

-110
$500+ offered for betting!

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Buffalo Bills vs Atlanta Falcons Picks
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