Los Angeles Chargers vs Philadelphia Eagles Prediction & Picks - NFL

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Los Angeles Chargers
12/8/25 20:15
Philadelphia Eagles

Prediction:

 

LA Chargers ML

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 by Travis Pulver | in NFL Picks

The Philadelphia Eagles will try to get back on the right side of the scoreboard this week when they head out to the West Coast to take on the Los Angeles Chargers on Monday Night Football. Gametime at SoFi Stadium in Inglewood, CA, is scheduled for 8:15 p.m. EST.

Philadelphia comes into the game in control of the NFC East, but losers of their last two games (vs. the Cowboys and Bears). After getting out to a 21-point lead early in the second quarter vs. the Cowboys, they were outscored 24-0 the rest of the way. Against the Bears, the offense never really got on track as the Chicago offense dictated the pace of the game; a late fourth-quarter touchdown made the final score look closer than the game really was. As for the Chargers, they’ve had some issues in recent weeks, but the big concern this week is the health of QB Justin Herbert, who recently had surgery on his non-throwing hand. He has been limited in practice this week and is considered questionable for Monday’s game. If he doesn’t go, Trey Lance would get the start, which would undoubtedly lead to a run-heavy approach for the game against an Eagles defense that will be down one of its best players in Jalen Carter.

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Los Angeles Chargers vs Philadelphia Eagles Form

Table

Teams Pts P W L
9 Los Angeles Chargers
0.647 17 11 6
10 Philadelphia Eagles
0.647 17 11 6

Los Angeles Chargers and Philadelphia Eagles Latest Matches

Los Angeles Chargers
Los Angeles Chargers Latest matches
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 30, 2025 - NFL

Los Angeles Chargers
31 :  14
Las Vegas Raiders

Nov 16, 2025 - NFL

Jacksonville Jaguars
35 :  6
Los Angeles Chargers

Nov 9, 2025 - NFL

Los Angeles Chargers
25 :  10
Pittsburgh Steelers

Nov 2, 2025 - NFL

Tennessee Titans
20 :  27
Los Angeles Chargers

Oct 23, 2025 - NFL

Los Angeles Chargers
37 :  10
Minnesota Vikings

Oct 19, 2025 - NFL

Los Angeles Chargers
24 :  38
Indianapolis Colts
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 30, 2025 - NFL

Los Angeles Chargers
31 :  14
Las Vegas Raiders

Nov 9, 2025 - NFL

Los Angeles Chargers
25 :  10
Pittsburgh Steelers

Oct 23, 2025 - NFL

Los Angeles Chargers
37 :  10
Minnesota Vikings

Oct 19, 2025 - NFL

Los Angeles Chargers
24 :  38
Indianapolis Colts

Oct 5, 2025 - NFL

Los Angeles Chargers
10 :  27
Washington Commanders

Sep 21, 2025 - NFL

Los Angeles Chargers
23 :  20
Denver Broncos
L W L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Nov 16, 2025 - NFL

Jacksonville Jaguars
35 :  6
Los Angeles Chargers

Nov 2, 2025 - NFL

Tennessee Titans
20 :  27
Los Angeles Chargers

Oct 12, 2025 - NFL

Miami Dolphins
27 :  29
Los Angeles Chargers

Sep 28, 2025 - NFL

New York Giants
21 :  18
Los Angeles Chargers

Sep 15, 2025 - NFL

Las Vegas Raiders
9 :  20
Los Angeles Chargers

Jan 11, 2025 - NFL

Houston Texans
32 :  12
Los Angeles Chargers
Philadelphia Eagles
Philadelphia Eagles Latest matches
W W W W L L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 28, 2025 - NFL

Philadelphia Eagles
15 :  24
Chicago Bears

Nov 23, 2025 - NFL

Dallas Cowboys
24 :  21
Philadelphia Eagles

Nov 16, 2025 - NFL

Philadelphia Eagles
16 :  9
Detroit Lions

Nov 10, 2025 - NFL

Green Bay Packers
7 :  10
Philadelphia Eagles

Oct 26, 2025 - NFL

Philadelphia Eagles
38 :  20
New York Giants

Oct 19, 2025 - NFL

Minnesota Vikings
22 :  28
Philadelphia Eagles
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 28, 2025 - NFL

Philadelphia Eagles
15 :  24
Chicago Bears

Nov 16, 2025 - NFL

Philadelphia Eagles
16 :  9
Detroit Lions

Oct 26, 2025 - NFL

Philadelphia Eagles
38 :  20
New York Giants

Oct 5, 2025 - NFL

Philadelphia Eagles
17 :  21
Denver Broncos

Sep 21, 2025 - NFL

Philadelphia Eagles
33 :  26
Los Angeles Rams

Sep 4, 2025 - NFL

Philadelphia Eagles
24 :  20
Dallas Cowboys
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Nov 23, 2025 - NFL

Dallas Cowboys
24 :  21
Philadelphia Eagles

Nov 10, 2025 - NFL

Green Bay Packers
7 :  10
Philadelphia Eagles

Oct 19, 2025 - NFL

Minnesota Vikings
22 :  28
Philadelphia Eagles

Oct 9, 2025 - NFL

New York Giants
34 :  17
Philadelphia Eagles

Sep 28, 2025 - NFL

Tampa Bay Buccaneers
25 :  31
Philadelphia Eagles

Sep 14, 2025 - NFL

Kansas City Chiefs
17 :  20
Philadelphia Eagles

Los Angeles Chargers - Philadelphia Eagles Key Points

  1. The Chargers lead the all-time series vs. the Eagles 8-5, but the two teams have not played since the 2021 season.
  2. Los Angeles is 5-6-1 ATS this season, while Philadelphia is 7-5.
  3. The OVER is 6-6 for the Chargers and 5-7 for the Eagles.
  4. Betting Public: 19% of moneyline tickets and 11% of the handle are on the Chargers.
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Our Los Angeles Chargers vs Philadelphia Eagles Prediction

Philadelphia’s offense has been a giant question mark all season; they’ve never really established the run, and the passing game has been hit-or-miss. But they’ve managed to stay on the right side of the scoreboard more often than not, thanks to their defense. However, they have not been strong against the run (24th) and will be down Jalen Carter in the interior of the line. Herbert’s health is a concern, but I see the Chargers exploiting the hole Carter’s absence leaves in their run defense while LA’s top-five defense (total yards) keeps the Eagles offense from revving up.

Our Eagles vs. Chargers Pick: LA Chargers ML  

Prediction:

 

LA Chargers ML

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Los Angeles Chargers vs Philadelphia Eagles Picks