Los Angeles Chargers vs Philadelphia Eagles Prediction & Picks - NFL
USA - NFL
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Travis Pulver | in NFL Picks
The Philadelphia Eagles will try to get back on the right side of the scoreboard this week when they head out to the West Coast to take on the Los Angeles Chargers on Monday Night Football. Gametime at SoFi Stadium in Inglewood, CA, is scheduled for 8:15 p.m. EST.
Philadelphia comes into the game in control of the NFC East, but losers of their last two games (vs. the Cowboys and Bears). After getting out to a 21-point lead early in the second quarter vs. the Cowboys, they were outscored 24-0 the rest of the way. Against the Bears, the offense never really got on track as the Chicago offense dictated the pace of the game; a late fourth-quarter touchdown made the final score look closer than the game really was. As for the Chargers, they’ve had some issues in recent weeks, but the big concern this week is the health of QB Justin Herbert, who recently had surgery on his non-throwing hand. He has been limited in practice this week and is considered questionable for Monday’s game. If he doesn’t go, Trey Lance would get the start, which would undoubtedly lead to a run-heavy approach for the game against an Eagles defense that will be down one of its best players in Jalen Carter.
Limited Offer. Currently at Caesars Sportsbook
Los Angeles Chargers vs Philadelphia Eagles Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
9
|
0.647 | 17 | 11 | 6 |
|
10
|
0.647 | 17 | 11 | 6 |
Los Angeles Chargers and Philadelphia Eagles Latest Matches
4/6 (67%)
2/6 (33%)
Nov 30, 2025 - NFL
Nov 16, 2025 - NFL
Nov 9, 2025 - NFL
Nov 2, 2025 - NFL
Oct 23, 2025 - NFL
Oct 19, 2025 - NFL
4/6 (67%)
2/6 (33%)
Nov 30, 2025 - NFL
Nov 9, 2025 - NFL
Oct 23, 2025 - NFL
Oct 19, 2025 - NFL
Oct 5, 2025 - NFL
Sep 21, 2025 - NFL
3/6 (50%)
3/6 (50%)
Nov 16, 2025 - NFL
Nov 2, 2025 - NFL
Oct 12, 2025 - NFL
Sep 28, 2025 - NFL
Sep 15, 2025 - NFL
Jan 11, 2025 - NFL
4/6 (67%)
2/6 (33%)
Nov 28, 2025 - NFL
Nov 23, 2025 - NFL
Nov 16, 2025 - NFL
Nov 10, 2025 - NFL
Oct 26, 2025 - NFL
Oct 19, 2025 - NFL
4/6 (67%)
2/6 (33%)
Nov 28, 2025 - NFL
Nov 16, 2025 - NFL
Oct 26, 2025 - NFL
Oct 5, 2025 - NFL
Sep 21, 2025 - NFL
Sep 4, 2025 - NFL
4/6 (67%)
2/6 (33%)
Nov 23, 2025 - NFL
Nov 10, 2025 - NFL
Oct 19, 2025 - NFL
Oct 9, 2025 - NFL
Sep 28, 2025 - NFL
Sep 14, 2025 - NFL
Los Angeles Chargers - Philadelphia Eagles Key Points
- The Chargers lead the all-time series vs. the Eagles 8-5, but the two teams have not played since the 2021 season.
- Los Angeles is 5-6-1 ATS this season, while Philadelphia is 7-5.
- The OVER is 6-6 for the Chargers and 5-7 for the Eagles.
- Betting Public: 19% of moneyline tickets and 11% of the handle are on the Chargers.
Limited Offer. Currently at Caesars Sportsbook
Our Los Angeles Chargers vs Philadelphia Eagles Prediction
Philadelphia’s offense has been a giant question mark all season; they’ve never really established the run, and the passing game has been hit-or-miss. But they’ve managed to stay on the right side of the scoreboard more often than not, thanks to their defense. However, they have not been strong against the run (24th) and will be down Jalen Carter in the interior of the line. Herbert’s health is a concern, but I see the Chargers exploiting the hole Carter’s absence leaves in their run defense while LA’s top-five defense (total yards) keeps the Eagles offense from revving up.
Our Eagles vs. Chargers Pick: LA Chargers ML
All tips are fully researched and given in good faith, but profits cannot be guaranteed.