Cleveland Guardians vs Washington Nationals Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
5/27/26 13:10
Washington Nationals

Prediction:

 

CLE Guardians to Cover -1.5 Run Line

+105
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 by Edgar Jibran | in MLB Picks

The last game of the MLB series between the Washington Nationals and Cleveland Guardians will take place this Wednesday morning; it is worth noting that the odds again favor the Guardians to win. Nevertheless, it cannot be ignored that the Nationals already secured winning the series after an astonishing performance in the first two games.

Furthermore, it should be noted that, despite the Nationals currently being 8.5 games behind the Atlanta Braves in the NL East Division, they still have plenty of chances of reaching the playoffs via Wild Card spots. With this objective in mind, the Nationals’ opening pitcher, Miles Mikolas, is expected to sustain his recent performance, as he allowed only 5 runs in his last 13.3 innings.

Meanwhile, the Cleveland Guardians are definitely taking this last game of the series very seriously, as keeping at least a 3.5-game advantage over the Chicago White Sox is key for them to avoid any kind of pressure. Considering these factors, it is not surprising to find Gavin Williams on the pitching mound, as he is well-known for being the best Guardians starter with 84 strikeouts throughout the season.

Cleveland Guardians vs Washington Nationals Form

Table

Teams Pts P W L
12 Cleveland Guardians
0.518 83 43 40
13 Washington Nationals
0.5 84 42 42

Cleveland Guardians and Washington Nationals Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 26, 2026 - MLB

Cleveland Guardians
3 :  6
Washington Nationals

May 25, 2026 - MLB

Cleveland Guardians
2 :  10
Washington Nationals

May 24, 2026 - MLB

Philadelphia Phillies
1 :  3
Cleveland Guardians

May 23, 2026 - MLB

Philadelphia Phillies
3 :  0
Cleveland Guardians

May 22, 2026 - MLB

Philadelphia Phillies
0 :  1
Cleveland Guardians

May 21, 2026 - MLB

Detroit Tigers
1 :  3
Cleveland Guardians
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 26, 2026 - MLB

Cleveland Guardians
3 :  6
Washington Nationals

May 25, 2026 - MLB

Cleveland Guardians
2 :  10
Washington Nationals

May 17, 2026 - MLB

Cleveland Guardians
10 :  3
Cincinnati Reds

May 16, 2026 - MLB

Cleveland Guardians
7 :  4
Cincinnati Reds

May 15, 2026 - MLB

Cleveland Guardians
6 :  7
Cincinnati Reds

May 13, 2026 - MLB

Cleveland Guardians
4 :  2
Los Angeles Angels
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 24, 2026 - MLB

Philadelphia Phillies
1 :  3
Cleveland Guardians

May 23, 2026 - MLB

Philadelphia Phillies
3 :  0
Cleveland Guardians

May 22, 2026 - MLB

Philadelphia Phillies
0 :  1
Cleveland Guardians

May 21, 2026 - MLB

Detroit Tigers
1 :  3
Cleveland Guardians

May 20, 2026 - MLB

Detroit Tigers
2 :  3
Cleveland Guardians

May 19, 2026 - MLB

Detroit Tigers
3 :  4
Cleveland Guardians
Washington Nationals
Washington Nationals Latest matches
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 26, 2026 - MLB

Cleveland Guardians
3 :  6
Washington Nationals

May 25, 2026 - MLB

Cleveland Guardians
2 :  10
Washington Nationals

May 24, 2026 - MLB

Atlanta Braves
1 :  2
Washington Nationals

May 23, 2026 - MLB

Atlanta Braves
0 :  2
Washington Nationals

May 22, 2026 - MLB

Atlanta Braves
5 :  4
Washington Nationals

May 21, 2026 - MLB

Washington Nationals
1 :  2
New York Mets
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 21, 2026 - MLB

Washington Nationals
1 :  2
New York Mets

May 20, 2026 - MLB

Washington Nationals
8 :  4
New York Mets

May 19, 2026 - MLB

Washington Nationals
9 :  6
New York Mets

May 18, 2026 - MLB

Washington Nationals
7 :  16
New York Mets

May 17, 2026 - MLB

Washington Nationals
3 :  7
Baltimore Orioles

May 16, 2026 - MLB

Washington Nationals
13 :  3
Baltimore Orioles
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 26, 2026 - MLB

Cleveland Guardians
3 :  6
Washington Nationals

May 25, 2026 - MLB

Cleveland Guardians
2 :  10
Washington Nationals

May 24, 2026 - MLB

Atlanta Braves
1 :  2
Washington Nationals

May 23, 2026 - MLB

Atlanta Braves
0 :  2
Washington Nationals

May 22, 2026 - MLB

Atlanta Braves
5 :  4
Washington Nationals

May 14, 2026 - MLB

Cincinnati Reds
15 :  1
Washington Nationals

Cleveland Guardians against Washington Nationals : Head to Head (H2H)

Cleveland Guardians

50 %

Washington Nationals

50 %

May 26, 2026 - MLB

Cleveland Guardians
3 :  6
Washington Nationals

May 25, 2026 - MLB

Cleveland Guardians
2 :  10
Washington Nationals

May 7, 2025 - MLB

Washington Nationals
6 :  8
Cleveland Guardians

May 31, 2024 - MLB

Cleveland Guardians
7 :  1
Washington Nationals

Cleveland Guardians - Washington Nationals Key Points

  1. The Washington Nationals have James Wood their best batter of the season, as he has scored 15 home runs and keeps an on-base percentage of .413.
  2. The Cleveland Guardians expect Gavin Williams to emulate the fantastic performance he had against the Phillies, as he didn’t earn any runs in 8.0 innings.
  3. The Washington Nationals won their third straight series, so they are expected to shortly reach the Wild Card spots in the National League standings.
  4. The Cleveland Guardians haven’t scored more than 3 runs during their last seven straight games.

Our Cleveland Guardians vs Washington Nationals Prediction

With all these factors in mind, the Cleveland Guardians are expected to dominate the early game due to performance differences between the opening pitchers. However, the Nationals are on one of their better streaks of the season, so thinking about a dominant victory by the Guardians doesn't make sense at all.

Summarizing, even though the Guardians aren't expected to lose this third game of the series, the most realistic scenario for them is winning by a maximum of 2-3 runs. Therefore, the pick for the Washington Nationals - Cleveland Guardians is: CLE Guardians to Cover -1.5 Run Line!

Prediction:

 

CLE Guardians to Cover -1.5 Run Line

+105
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Cleveland Guardians vs Washington Nationals Picks