Cleveland Guardians vs Washington Nationals Prediction & Picks - MLB
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After dominating Game One of the series, the Washington Nationals will be looking to continue their impressive form when they take on the Cleveland Guardians once again on Tuesday evening.
Curtis Mead was the star of the show for the Nationals in Game One, as he hit two of the visitors' six home runs. Whilst James Wood and Luis Garcia Jnr also contributed homers, plus four and three hits respectively, as the visitors cruised to a 10-2 victory.
It was a miserable night for the Guardians, with starting pitcher Tanner Bibee conceding a whopping five home runs in three innings. However, with star pitcher Joey Cantillo set to start in Game Two, the Guardians will be confident of bouncing back to set up a series decider on Wednesday.
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Cleveland Guardians vs Washington Nationals Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
16
|
0.492 | 120 | 59 | 61 |
|
19
|
0.487 | 119 | 58 | 61 |
Cleveland Guardians and Washington Nationals Latest Matches
4/6 (67%)
2/6 (33%)
May 25, 2026 - MLB
May 24, 2026 - MLB
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May 20, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 25, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
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May 13, 2026 - MLB
May 12, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
May 21, 2026 - MLB
May 20, 2026 - MLB
May 19, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 25, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
May 21, 2026 - MLB
May 20, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 21, 2026 - MLB
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 25, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
Cleveland Guardians against Washington Nationals : Head to Head (H2H)
67 %
33 %
May 25, 2026 - MLB
May 7, 2025 - MLB
May 31, 2024 - MLB
Cleveland Guardians - Washington Nationals Key Points
- Cleveland are 8-2 in their last 10 games
- Cleveland have won 5 of their last 7 at home
- Cleveland have conceded over 3 runs just once in their last 9 games
- Guardians starting pitcher Joey Cantillo is 4-1 for the season
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Our Cleveland Guardians vs Washington Nationals Prediction
We are expecting this to be a very different contest from Monday's first game, which was dominated by the Nationals.
Cleveland will be desperate to bounce back, and with Joey Cantillo starting on the mound, that's exactly what we are expecting them to do.
The bookies clearly agree, and make the Guardians fairly short priced favorites to pick up the win. Not only do we agree with that verdict, but we think you can boost your bet slightly by taking them to beat the -1 run line.
Our prediction for Cleveland Guardians vs Washington Nationals is: Guardians (-1) to win.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
