Chicago White Sox vs Washington Nationals Prediction & Picks - MLB

USA - MLB

Chicago White Sox
4/26/26 14:10
Washington Nationals

Prediction:

 

Over 8.5

-118
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 by Carlos Zabala | in MLB Picks

The White Sox are sporting their City Connect uniform, a blend of their colors and those of the Chicago Bulls, in their series against the Nationals. For a franchise that lost 100 games in 2025, this kind of change is generating renewed interest among their loyal fans. White Sox fans aren't expecting miracles, but they are hoping for a better performance than in recent dismal seasons, and after winning the series against the Diamondbacks in the desert, taking this series against the Nationals is crucial.

Murakami went inexplicably 0-for-5 in the second game of the series against the Nationals, which Washington won in extra innings when Sox reliever Leasure faltered. Even so, Murakami's performance doesn't diminish the positive aspects of the Japanese slugger's first season, who could be a contender for the MLB home run lead in the long run, as he currently has 11. He has ignited the White Sox dugout, and he has been joined by the solid work of shortstop Colson Montgomery, who has 7 home runs this season, and Miguel Vargas, who also hit 5.

Chicago White Sox vs Washington Nationals Form

Table

Teams Pts P W L
8 Chicago White Sox
0.531 81 43 38
13 Washington Nationals
0.5 84 42 42

Chicago White Sox and Washington Nationals Latest Matches

Chicago White Sox
Chicago White Sox Latest matches
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 25, 2026 - MLB

Chicago White Sox
3 :  6
Washington Nationals

Apr 24, 2026 - MLB

Chicago White Sox
5 :  4
Washington Nationals

Apr 23, 2026 - MLB

Arizona Diamondbacks
1 :  4
Chicago White Sox

Apr 22, 2026 - MLB

Arizona Diamondbacks
11 :  7
Chicago White Sox

Apr 21, 2026 - MLB

Arizona Diamondbacks
5 :  11
Chicago White Sox

Apr 19, 2026 - MLB

Athletics
4 :  7
Chicago White Sox
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 25, 2026 - MLB

Chicago White Sox
3 :  6
Washington Nationals

Apr 24, 2026 - MLB

Chicago White Sox
5 :  4
Washington Nationals

Apr 16, 2026 - MLB

Chicago White Sox
3 :  5
Tampa Bay Rays

Apr 15, 2026 - MLB

Chicago White Sox
3 :  8
Tampa Bay Rays

Apr 14, 2026 - MLB

Chicago White Sox
5 :  8
Tampa Bay Rays

Apr 8, 2026 - MLB

Chicago White Sox
3 :  5
Baltimore Orioles
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 23, 2026 - MLB

Arizona Diamondbacks
1 :  4
Chicago White Sox

Apr 22, 2026 - MLB

Arizona Diamondbacks
11 :  7
Chicago White Sox

Apr 21, 2026 - MLB

Arizona Diamondbacks
5 :  11
Chicago White Sox

Apr 19, 2026 - MLB

Athletics
4 :  7
Chicago White Sox

Apr 18, 2026 - MLB

Athletics
7 :  6
Chicago White Sox

Apr 17, 2026 - MLB

Athletics
2 :  9
Chicago White Sox
Washington Nationals
Washington Nationals Latest matches
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 25, 2026 - MLB

Chicago White Sox
3 :  6
Washington Nationals

Apr 24, 2026 - MLB

Chicago White Sox
5 :  4
Washington Nationals

Apr 23, 2026 - MLB

Washington Nationals
2 :  7
Atlanta Braves

Apr 22, 2026 - MLB

Washington Nationals
6 :  8
Atlanta Braves

Apr 21, 2026 - MLB

Washington Nationals
11 :  4
Atlanta Braves

Apr 20, 2026 - MLB

Washington Nationals
4 :  9
Atlanta Braves
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 23, 2026 - MLB

Washington Nationals
2 :  7
Atlanta Braves

Apr 22, 2026 - MLB

Washington Nationals
6 :  8
Atlanta Braves

Apr 21, 2026 - MLB

Washington Nationals
11 :  4
Atlanta Braves

Apr 20, 2026 - MLB

Washington Nationals
4 :  9
Atlanta Braves

Apr 19, 2026 - MLB

Washington Nationals
3 :  0
San Francisco Giants

Apr 18, 2026 - MLB

Washington Nationals
6 :  7
San Francisco Giants
L W L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 25, 2026 - MLB

Chicago White Sox
3 :  6
Washington Nationals

Apr 24, 2026 - MLB

Chicago White Sox
5 :  4
Washington Nationals

Apr 16, 2026 - MLB

Pittsburgh Pirates
7 :  8
Washington Nationals

Apr 15, 2026 - MLB

Pittsburgh Pirates
2 :  0
Washington Nationals

Apr 14, 2026 - MLB

Pittsburgh Pirates
4 :  5
Washington Nationals

Apr 13, 2026 - MLB

Pittsburgh Pirates
16 :  5
Washington Nationals

Chicago White Sox against Washington Nationals : Head to Head (H2H)

Chicago White Sox

50 %

Washington Nationals

50 %

Apr 25, 2026 - MLB

Chicago White Sox
3 :  6
Washington Nationals

Apr 24, 2026 - MLB

Chicago White Sox
5 :  4
Washington Nationals

Sep 28, 2025 - MLB

Washington Nationals
0 :  8
Chicago White Sox

Sep 27, 2025 - MLB

Washington Nationals
6 :  5
Chicago White Sox

Sep 26, 2025 - MLB

Washington Nationals
9 :  10
Chicago White Sox

Sep 19, 2023 - MLB

Washington Nationals
4 :  3
Chicago White Sox

Chicago White Sox - Washington Nationals Key Points

  1. Daylen Lile of the Nationals is batting .296 in 2026
  2. The Nationals are averaging 5.5 runs per game in MLB this season
  3. The Nationals are the third-leading stolen base team this season
  4. The Nationals' collective pitching ERA is 5.59

Our Chicago White Sox vs Washington Nationals Prediction

The Nats, like the Sox, don't seem likely to win the NL East, which the Braves lead, but they have some buzzworthy hitters, the first being Wood. The left fielder has been a direct contributor to many of the Nationals' runs this season, racking up 10 hits, 6 doubles, and 21 RBIs in 2026.

The two hot bats on either side, Wood and Murakami, went quiet in Game 2; it would be surprising if that happened again in Game 3. An offensive surge is expected.

Our prediction for White Sox vs Nationals is: Over 8.5.

Prediction:

 

Over 8.5

-118
$200 offered for betting!

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Chicago White Sox vs Washington Nationals Picks