Tennessee Titans vs Jacksonville Jaguars Prediction & Picks - NFL
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by Lou Aguila in NFL Picks
The Jacksonville Jaguars will go for their seventh straight victory on Sunday against the skidding Indianapolis Colts at Lucas Oil Stadium.
6-0 against the spread in their last six games, the Jaguars are given a -5.5-point handicap against the team they demolished by 17 points last December 7.
Current Form:
The Jaguars inched closer to locking up the AFC South Division following their 34-20 win over the Denver Broncos on December 21. Jacksonville’s six-game winning streak and rise to contention would never be possible without the stellar season from quarterback Trevor Lawrence, who has covered 3,489 passing yards with 26 touchdowns and 11 interceptions. The Jaguars rank 15th in passing yards (218.3) and 7th in points per game (27.3).
The Colts’ postseason hopes evaporated the moment they suffered a 27-48 beatdown at the hands of the San Francisco Giants on December 22. That marked Indianapolis’ fifth straight loss and sixth of their last seven games. After a promising 8-2 start, the Colts have experienced a collapse and never recovered following the season-ending injury to quarterback Daniel Jones (Achilles).
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Tennessee Titans vs Jacksonville Jaguars Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
|
4
|
0.75 | 16 | 12 | 0 | 4 |
|
31
|
0.188 | 16 | 3 | 0 | 13 |
Tennessee Titans and Jacksonville Jaguars Latest Matches
2/6 (33%)
0/6 (0%)
4/6 (67%)
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1/6 (17%)
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5/6 (83%)
Dec 28, 2025 - NFL
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2/6 (33%)
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4/6 (67%)
Dec 14, 2025 - NFL
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6/6 (100%)
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4/6 (67%)
0/6 (0%)
2/6 (33%)
Dec 14, 2025 - NFL
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5/6 (83%)
0/6 (0%)
1/6 (17%)
Dec 28, 2025 - NFL
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Tennessee Titans against Jacksonville Jaguars : Head to Head (H2H)
20 %
0 %
80 %
Nov 30, 2025 - NFL
Dec 29, 2024 - NFL
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Jan 7, 2023 - NFL
Tennessee Titans - Jacksonville Jaguars Key Points
- Jacksonville is 6-0 ATS in its last 6 games.
- Jacksonville is 10-2 ATS in its last 12 games against Indianapolis.
- Indianapolis is 2-5 ATS in its last 7 games.
- Indianapolis is 0-5 SU in its last 5 games.
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Our Tennessee Titans vs Jacksonville Jaguars Prediction
Fearless Forecast: The Jaguars will deal the coup de grace to the Colts with a convincing win on Sunday. Jacksonville blew out the Colts by 17 points in their first meeting and I wouldn’t be surprised if they won by more points, given Indianapolis’ dreadful situation. The injury to Daniel Jones has crippled the Colts’ offense significantly as they struggled to score more than 20 points against Jacksonville (19-36) and Seattle (16-18) before letting the 49ers rip them apart last week (27-48). Jacksonville is 6-0 ATS in its last 6 games and 10-2 ATS in its last 12 games against Indianapolis.
Our betting prediction for the Jacksonville Jaguars vs. the Indianapolis Colts: The Jaguars -5.5 points
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.