Cleveland Guardians vs Tampa Bay Rays Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
4/29/26 13:10
Tampa Bay Rays

Prediction:

 

The Rays will win

+100
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 by Lou Aguila | in MLB Picks

Red Hot Rays: The Tampa Bay Rays have won their last six games after another stellar pitching performance in a 1-0 shutout of the Cleveland Guardians in Game 2.

The Rays are dealing a lot of damage on both sides of the ball in this stretch. Ovcr the last five games, Tampa Bay has posted an impeccable 1.43 ERA and averaged 4.3 runs per game on a .232 BA.

Skidding Guardians: Meanwhile, the Guardians have suffered their fourth consecutive loss and dropped below .500 at 15-16, second in the American League Central.

they have managed to register a respectable 3.35 ERA over their last five outings, the offense has been lackluster over this stretch, generating only 3.0 runs per game on a .216 BA.

The Wrath of Rasmussen: The Rays will start Drew Rasmussen on Wednesday. Rasmussen has compiled a solid 2-0 record with a 2.45 ERA and 26 strikeouts across five starts.

He has led Tampa to a win in his last three starts, including a mound appearance on April 24, where he gave up one run over six innings to power Tampa Bay to a 6-2 win over Minnesota. Rasmussen has allowed only two runs in his last three starts against the Guardians, including a couple of shutout stints.

Up to $250 to bet on Cleveland Guardians - Tampa Bay Rays! 

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Cleveland Guardians vs Tampa Bay Rays Form

Table

Teams Pts P W L
4 Tampa Bay Rays
0.588 80 47 33
12 Cleveland Guardians
0.518 83 43 40

Cleveland Guardians and Tampa Bay Rays Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 28, 2026 - MLB

Cleveland Guardians
0 :  1
Tampa Bay Rays

Apr 27, 2026 - MLB

Cleveland Guardians
2 :  3
Tampa Bay Rays

Apr 26, 2026 - MLB

Toronto Blue Jays
4 :  2
Cleveland Guardians

Apr 25, 2026 - MLB

Toronto Blue Jays
5 :  3
Cleveland Guardians

Apr 24, 2026 - MLB

Toronto Blue Jays
6 :  8
Cleveland Guardians

Apr 22, 2026 - MLB

Cleveland Guardians
0 :  2
Houston Astros
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2026 - MLB

Cleveland Guardians
0 :  1
Tampa Bay Rays

Apr 27, 2026 - MLB

Cleveland Guardians
2 :  3
Tampa Bay Rays

Apr 22, 2026 - MLB

Cleveland Guardians
0 :  2
Houston Astros

Apr 21, 2026 - MLB

Cleveland Guardians
8 :  5
Houston Astros

Apr 20, 2026 - MLB

Cleveland Guardians
2 :  9
Houston Astros

Apr 19, 2026 - MLB

Cleveland Guardians
8 :  4
Baltimore Orioles
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 26, 2026 - MLB

Toronto Blue Jays
4 :  2
Cleveland Guardians

Apr 25, 2026 - MLB

Toronto Blue Jays
5 :  3
Cleveland Guardians

Apr 24, 2026 - MLB

Toronto Blue Jays
6 :  8
Cleveland Guardians

Apr 15, 2026 - MLB

St. Louis Cardinals
5 :  3
Cleveland Guardians

Apr 14, 2026 - MLB

St. Louis Cardinals
6 :  5
Cleveland Guardians

Apr 13, 2026 - MLB

St. Louis Cardinals
3 :  9
Cleveland Guardians
Tampa Bay Rays
Tampa Bay Rays Latest matches
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Apr 28, 2026 - MLB

Cleveland Guardians
0 :  1
Tampa Bay Rays

Apr 27, 2026 - MLB

Cleveland Guardians
2 :  3
Tampa Bay Rays

Apr 26, 2026 - MLB

Tampa Bay Rays
4 :  2
Minnesota Twins

Apr 25, 2026 - MLB

Tampa Bay Rays
6 :  1
Minnesota Twins

Apr 24, 2026 - MLB

Tampa Bay Rays
6 :  2
Minnesota Twins

Apr 22, 2026 - MLB

Tampa Bay Rays
6 :  1
Cincinnati Reds
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 26, 2026 - MLB

Tampa Bay Rays
4 :  2
Minnesota Twins

Apr 25, 2026 - MLB

Tampa Bay Rays
6 :  1
Minnesota Twins

Apr 24, 2026 - MLB

Tampa Bay Rays
6 :  2
Minnesota Twins

Apr 22, 2026 - MLB

Tampa Bay Rays
6 :  1
Cincinnati Reds

Apr 21, 2026 - MLB

Tampa Bay Rays
6 :  12
Cincinnati Reds

Apr 20, 2026 - MLB

Tampa Bay Rays
1 :  6
Cincinnati Reds
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 28, 2026 - MLB

Cleveland Guardians
0 :  1
Tampa Bay Rays

Apr 27, 2026 - MLB

Cleveland Guardians
2 :  3
Tampa Bay Rays

Apr 19, 2026 - MLB

Pittsburgh Pirates
6 :  3
Tampa Bay Rays

Apr 18, 2026 - MLB

Pittsburgh Pirates
7 :  8
Tampa Bay Rays

Apr 17, 2026 - MLB

Pittsburgh Pirates
5 :  1
Tampa Bay Rays

Apr 16, 2026 - MLB

Chicago White Sox
3 :  5
Tampa Bay Rays

Cleveland Guardians against Tampa Bay Rays : Head to Head (H2H)

Cleveland Guardians

50 %

Tampa Bay Rays

50 %

Apr 28, 2026 - MLB

Cleveland Guardians
0 :  1
Tampa Bay Rays

Apr 27, 2026 - MLB

Cleveland Guardians
2 :  3
Tampa Bay Rays

Sep 7, 2025 - MLB

Tampa Bay Rays
1 :  2
Cleveland Guardians

Sep 6, 2025 - MLB

Tampa Bay Rays
2 :  3
Cleveland Guardians

Sep 5, 2025 - MLB

Tampa Bay Rays
1 :  7
Cleveland Guardians

Sep 4, 2025 - MLB

Tampa Bay Rays
4 :  2
Cleveland Guardians

Cleveland Guardians - Tampa Bay Rays Key Points

  1. Tampa Bay is 8-2 SU in its last 10 games on the road.
  2. Tampa Bay is 6-0 SU in its last 6 games.
  3. Cleveland is 1-5 SU in its last 6 games.
  4. Cleveland is 1-4 SU in its last 5 games at home.
Up to $250 to bet on Cleveland Guardians - Tampa Bay Rays! 

Limited Offer. Currently at Caesars Sportsbook

Our Cleveland Guardians vs Tampa Bay Rays Prediction

The Rays are in good shape to extend their win streak, making them a sharp play at +100 moneyline at Caesars Sportsbook. The offense might not be explosive, but their pitching has been flat-out suffocating, particularly during this recent five-game stretch.

Rasmussen will continue to punish the Guardians, who are already suffering at the plate (4.0 runs per game on a .226 BA this season). His duel with Cleveland's Gavin Williams is going to be fun to watch, but the latter's subpar performance against Toronto on April 24 (6 earned runs over six innings) makes him vulnerable to the Rays, who average 4.6 runs per game on the road this season.

Tampa has been terrific on the road as of late. They are 8-2 SU in their last 10 games on the road. Cleveland is 3-4 in their last 7 home games. 

Our betting prediction for the Tampa Bay Rays vs. the Cleveland Guardians: The Rays will win.

Prediction:

 

The Rays will win

+100
$250 offered for betting!

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Cleveland Guardians vs Tampa Bay Rays Picks