Cleveland Guardians vs Tampa Bay Rays Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Travis Pulver | in MLB Picks
The Cleveland Guardians (15-14, 8-5 Home) will try to turn things around when they begin a three-game series with the Tampa Bay Rays at home on Monday, April 27. First Pitch at Progressive Field in Cleveland, OH, is scheduled for 6:10 p.m. EST with coverage provided by MLB.TV.
Cleveland is coming back home after a short, three-game road trip to Toronto to face the Blue Jays. Game One went well for them on Friday as they won, 8-6. But then they dropped Game Two on Saturday, 5-3, and the finale on Sunday, 4-2. Tampa Bay, on the other hand, swept the Twins at home over the weekend and is working on a four-game winning streak.
Parker Messick will get the start for the Guardians. Messick is 3-0 in five starts with a 1.76 ERA and a 0.88 WHIP. However, after allowing one run across his first three starts, he gave up five in his last two starts, causing his ERA to go from 0.51 to 1.76. As for the Rays, Steven Matz is scheduled to start. Matz is 3-1 in five starts with a 4.81 ERA and a 1.23 WHIP. He has given up at least one earned run in every start and four in his first and last starts.
Limited Offer. Currently at DraftKings
Cleveland Guardians vs Tampa Bay Rays Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
4
|
0.588 | 80 | 47 | 33 |
|
12
|
0.518 | 83 | 43 | 40 |
Cleveland Guardians and Tampa Bay Rays Latest Matches
2/6 (33%)
4/6 (67%)
Apr 26, 2026 - MLB
Apr 25, 2026 - MLB
Apr 24, 2026 - MLB
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 20, 2026 - MLB
3/6 (50%)
3/6 (50%)
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 20, 2026 - MLB
Apr 19, 2026 - MLB
Apr 18, 2026 - MLB
Apr 17, 2026 - MLB
2/6 (33%)
4/6 (67%)
Apr 26, 2026 - MLB
Apr 25, 2026 - MLB
Apr 24, 2026 - MLB
Apr 15, 2026 - MLB
Apr 14, 2026 - MLB
Apr 13, 2026 - MLB
4/6 (67%)
2/6 (33%)
Apr 26, 2026 - MLB
Apr 25, 2026 - MLB
Apr 24, 2026 - MLB
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 20, 2026 - MLB
4/6 (67%)
2/6 (33%)
Apr 26, 2026 - MLB
Apr 25, 2026 - MLB
Apr 24, 2026 - MLB
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 20, 2026 - MLB
4/6 (67%)
2/6 (33%)
Apr 19, 2026 - MLB
Apr 18, 2026 - MLB
Apr 17, 2026 - MLB
Apr 16, 2026 - MLB
Apr 15, 2026 - MLB
Apr 14, 2026 - MLB
Cleveland Guardians against Tampa Bay Rays : Head to Head (H2H)
83 %
17 %
Sep 7, 2025 - MLB
Sep 6, 2025 - MLB
Sep 5, 2025 - MLB
Sep 4, 2025 - MLB
Aug 27, 2025 - MLB
Aug 26, 2025 - MLB
Cleveland Guardians - Tampa Bay Rays Key Points
- Cleveland leads the all-time series vs. Tampa Bay, 114-86.
- Cleveland is 15-13 ATS (run line) this season; Tampa Bay is 15-11.
- The OVER is 15-13 for the Guardians and 16-8-2 for the Rays.
- Betting Public: 69% of moneyline tickets and 64% of the handle are on Cleveland.
Limited Offer. Currently at DraftKings
Our Cleveland Guardians vs Tampa Bay Rays Prediction
Neither lineup has been lighting opponents up over the last week. Both have hit around .250, but the Rays have averaged just under five runs per game while the Guardians have averaged just under four per game. Matz has a solid history against the Cleveland lineup (.123 BA in 57 at-bats), but Messick has been pitching much better than him this season. It’s hard to say whether the Guardians can cover the run line, but they should win this game.
Our Tampa Bay vs. Cleveland Pick: Guardians ML
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
