Seattle Mariners vs St. Louis Cardinals Prediction & Picks - MLB

USA - MLB

Seattle Mariners
9/10/25 21:40
St. Louis Cardinals

Prediction:

 

Mariners -1.5.

-108
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 by Carlos Zabala | in MLB Picks

The Mariners have a five-man starting rotation with notable career numbers. Their latest trade deadline additions make them a team that will easily be in the top 7 of MLB's most home run-hitting teams. They have speed on the bases, excellent defense, and, if that weren't enough, a city rooting for them to win their first World Series.

There are no excuses for the Mariners to miss the playoffs this season, so a solid September like the one they're having is necessary to secure the last Wild Card or take the division lead from the Astros.

The Mariners won their last four games with home runs; it was a good run that began with a 10-2 thrashing of the Braves on September 2nd, when Raleigh, Naylor, and Suárez homered, and Julio Rodríguez hit two home runs. The next game, they won 18-2. Another day, Suárez had two home runs, and Raleigh hit his 53rd of the season.

The Mariners won the first game of the series against the Cardinals 4-2, and in Tuesday's 5-3 victory, Arozarena hit his 27th home run of the year and Naylor his 19th.

Seattle Mariners vs St. Louis Cardinals Form

Table

Teams Pts P W L
8 Seattle Mariners
0.556 162 90 72
20 St. Louis Cardinals
0.481 162 78 84

Seattle Mariners and St. Louis Cardinals Latest Matches

Seattle Mariners
Seattle Mariners Latest matches
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 9, 2025 - MLB

Seattle Mariners
5 :  3
St. Louis Cardinals

Sep 8, 2025 - MLB

Seattle Mariners
4 :  2
St. Louis Cardinals

Sep 7, 2025 - MLB

Atlanta Braves
2 :  18
Seattle Mariners

Sep 6, 2025 - MLB

Atlanta Braves
2 :  10
Seattle Mariners

Sep 5, 2025 - MLB

Atlanta Braves
4 :  1
Seattle Mariners

Sep 3, 2025 - MLB

Tampa Bay Rays
9 :  4
Seattle Mariners
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 9, 2025 - MLB

Seattle Mariners
5 :  3
St. Louis Cardinals

Sep 8, 2025 - MLB

Seattle Mariners
4 :  2
St. Louis Cardinals

Aug 27, 2025 - MLB

Seattle Mariners
4 :  3
San Diego Padres

Aug 26, 2025 - MLB

Seattle Mariners
6 :  7
San Diego Padres

Aug 25, 2025 - MLB

Seattle Mariners
9 :  6
San Diego Padres

Aug 24, 2025 - MLB

Seattle Mariners
11 :  4
Athletics
L L L L W W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 7, 2025 - MLB

Atlanta Braves
2 :  18
Seattle Mariners

Sep 6, 2025 - MLB

Atlanta Braves
2 :  10
Seattle Mariners

Sep 5, 2025 - MLB

Atlanta Braves
4 :  1
Seattle Mariners

Sep 3, 2025 - MLB

Tampa Bay Rays
9 :  4
Seattle Mariners

Sep 2, 2025 - MLB

Tampa Bay Rays
6 :  5
Seattle Mariners

Sep 1, 2025 - MLB

Tampa Bay Rays
10 :  2
Seattle Mariners
St. Louis Cardinals
St. Louis Cardinals Latest matches
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 9, 2025 - MLB

Seattle Mariners
5 :  3
St. Louis Cardinals

Sep 8, 2025 - MLB

Seattle Mariners
4 :  2
St. Louis Cardinals

Sep 7, 2025 - MLB

St. Louis Cardinals
4 :  3
San Francisco Giants

Sep 6, 2025 - MLB

St. Louis Cardinals
3 :  2
San Francisco Giants

Sep 5, 2025 - MLB

St. Louis Cardinals
2 :  8
San Francisco Giants

Sep 3, 2025 - MLB

St. Louis Cardinals
5 :  1
Athletics
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 7, 2025 - MLB

St. Louis Cardinals
4 :  3
San Francisco Giants

Sep 6, 2025 - MLB

St. Louis Cardinals
3 :  2
San Francisco Giants

Sep 5, 2025 - MLB

St. Louis Cardinals
2 :  8
San Francisco Giants

Sep 3, 2025 - MLB

St. Louis Cardinals
5 :  1
Athletics

Sep 2, 2025 - MLB

St. Louis Cardinals
2 :  1
Athletics

Sep 1, 2025 - MLB

St. Louis Cardinals
3 :  11
Athletics
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 9, 2025 - MLB

Seattle Mariners
5 :  3
St. Louis Cardinals

Sep 8, 2025 - MLB

Seattle Mariners
4 :  2
St. Louis Cardinals

Aug 31, 2025 - MLB

Cincinnati Reds
7 :  4
St. Louis Cardinals

Aug 30, 2025 - MLB

Cincinnati Reds
2 :  4
St. Louis Cardinals

Aug 29, 2025 - MLB

Cincinnati Reds
5 :  7
St. Louis Cardinals

Aug 24, 2025 - MLB

Tampa Bay Rays
7 :  2
St. Louis Cardinals

Seattle Mariners against St. Louis Cardinals : Head to Head (H2H)

Seattle Mariners

100 %

St. Louis Cardinals

0 %

Sep 9, 2025 - MLB

Seattle Mariners
5 :  3
St. Louis Cardinals

Sep 8, 2025 - MLB

Seattle Mariners
4 :  2
St. Louis Cardinals

Sep 8, 2024 - MLB

St. Louis Cardinals
4 :  10
Seattle Mariners

Apr 22, 2023 - MLB

Seattle Mariners
5 :  4
St. Louis Cardinals

Seattle Mariners - St. Louis Cardinals Key Points

  1. Muñoz earned his 34th save of the season with the Mariners on Tuesday
  2. The Mariners hit 210 home runs, the second-most home runs in 2025
  3. The Mariners have the fourth-most stolen bases in MLB this season with 141
  4. The Mariners have a 43-27 record at T-Mobile Park

Our Seattle Mariners vs St. Louis Cardinals Prediction

A lot is in flux for the Mariners in 2025. It's impossible not to mention the great season of Cal Raleigh, who is the betting favorite behind Judge to win the MVP.

Raleigh is a two-handed hitter who, at a pitching park like T-Mobile, has led MLB in home runs all year, even playing catcher every day.

In addition, the Mariners have re-signed Suárez, who was a significant player at the trade deadline and currently ranks fourth in the home run list this season.

As if that weren't enough, Dominican Julio Rodríguez is having a splendid second half. The Mariners should win on Wednesday.

Our prediction for Mariners vs Cardinals is: Mariners -1.5.

Prediction:

 

Mariners -1.5.

-108
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Seattle Mariners vs St. Louis Cardinals Picks