New York Mets vs St. Louis Cardinals Prediction & Picks - MLB
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by Erik Gibbs in MLB Picks
The New York Mets and the St. Louis Cardinals are set to wrap up their four-game series on Sunday, with the Mets looking to close things out on a high note. New York has controlled the series from the outset, winning the first two games and asserting themselves as early-season contenders in the National League East. After a few underwhelming years, the Mets are eyeing a return to October baseball, with hopes of capturing their first NL pennant since 2015.
St. Louis, meanwhile, has continued to struggle mightily on the road. Entering Saturday’s game, the Cardinals had dropped five straight away from home, and a major factor in their woes has been a glaring lack of plate discipline.
In their last five road games, they’ve struck out at least ten times in each contest. The trend has continued against the Mets, with New York’s starters racking up strikeouts with ease—26 combined through the first two games, including 15 punchouts on Friday alone.
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New York Mets vs St. Louis Cardinals Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
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14
|
0.512 | 162 | 83 | 79 |
|
20
|
0.481 | 162 | 78 | 84 |
New York Mets and St. Louis Cardinals Latest Matches
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New York Mets against St. Louis Cardinals : Head to Head (H2H)
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New York Mets - St. Louis Cardinals Key Points
- The Mets are 6-0 SU in their last 6 games vs. the Cardinals
- The Cardinals are 1-7 in their last 8 road games
- The Mets are 4-1 in leading after 5 innings vs. the Cardinals
- The Cardinals are 5-1 covering the F5 run line in their last 6 games
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Our New York Mets vs St. Louis Cardinals Prediction
New York’s pitching staff, particularly the starters, has played a key role in keeping the Cardinals off balance. David Peterson delivered nine strikeouts in his outing, tying his season high, despite not making it out of the sixth inning. On Thursday, Griffin Canning worked six solid innings and fanned eight—a notable stat given that he had only managed 13 strikeouts over his first 15 innings this year.
Offensively, the Mets are starting to heat up as well. Mark Vientos, who got off to a slow start in 2025, has found his rhythm at the plate. Riding a six-game hitting streak, Vientos has collected extra-base hits in four of those games and has homered in back-to-back contests.
With a lineup anchored by stars like Pete Alonso and Juan Soto, the Mets have more than enough firepower to continue their winning ways. They’ve also performed well at home this season and have dominated recent meetings with the Cardinals. Unless St. Louis can tighten up at the plate and get a quality start from the mound, the Mets are in a strong position to take the series and keep their momentum rolling. Our prediction for New York Mets vs. St. Louis Cardinals: Mets to win.
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