Milwaukee Brewers vs St. Louis Cardinals Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Edgar Jibran | in MLB Picks
The last game in the MLB series of the St. Louis Cardinals at Milwaukee Brewers will take place this Wednesday morning at 11:40 am CST. For this game, the odds are logically supporting the Brewers to get a shutout over the Cardinals, as that would allow them to increase the gap against them in the NL Central Division standings.
However, the St. Louis Cardinals are clearly expected to show a better offensive performance after scoring only 1 run in the first two games in Milwaukee. Furthermore, their opening pitcher, May Dustin, is expected to increase his performance to allow the Cardinals to at least remain in Wild Card spots after losing this series against the Brewers.
On the Milwaukee Brewers’ side, this team has proven to have a strong mentality to immediately recover from losing their series against the Los Angeles Dodgers. Nevertheless, not having announced their probable opening pitcher for this game 13 hours before the kickoff could translate into good planning before facing some relevant series against the Houston Astros and the San Francisco Giants soon.
Limited Offer. Currently at Caesars Sportsbook
Milwaukee Brewers vs St. Louis Cardinals Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
2
|
0.615 | 96 | 59 | 37 |
|
9
|
0.526 | 95 | 50 | 45 |
Milwaukee Brewers and St. Louis Cardinals Latest Matches
4/6 (67%)
2/6 (33%)
May 26, 2026 - MLB
May 25, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
May 20, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 26, 2026 - MLB
May 25, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
May 14, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 20, 2026 - MLB
May 19, 2026 - MLB
May 18, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
1/6 (17%)
5/6 (83%)
May 26, 2026 - MLB
May 25, 2026 - MLB
May 23, 2026 - MLB
May 23, 2026 - MLB
May 21, 2026 - MLB
May 20, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 21, 2026 - MLB
May 20, 2026 - MLB
May 19, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
2/6 (33%)
4/6 (67%)
May 26, 2026 - MLB
May 25, 2026 - MLB
May 23, 2026 - MLB
May 23, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
Milwaukee Brewers against St. Louis Cardinals : Head to Head (H2H)
67 %
33 %
May 26, 2026 - MLB
May 25, 2026 - MLB
May 6, 2026 - MLB
May 4, 2026 - MLB
Sep 21, 2025 - MLB
Sep 20, 2025 - MLB
Milwaukee Brewers - St. Louis Cardinals Key Points
- The St. Louis Cardinals have Dustin May, the fifth-best pitcher in terms of strikeouts, with 42 thrown this season.
- The Milwaukee Brewers scored 5 or more runs in three of their last five games, so it makes sense they are the second-best offense in the NL Central Division, with 157 runs scored.
- The St. Louis Cardinals haven’t scored more than 3 runs in road meetings against the Milwaukee Brewers since their 9-8 loss in September 2025.
- The Milwaukee Brewers have Brice Turang and Jake Bauers, the only two batters to reach a 0.800+ OPS this season.
Limited Offer. Currently at Caesars Sportsbook
Our Milwaukee Brewers vs St. Louis Cardinals Prediction
Taking all this into account, the Milwaukee Brewers' batting is on fire; nevertheless, keeping that powerful performance will be the main challenge for them to avoid falling in early rounds of the playoffs just like it happened during the 2025 season.
In conclusion, even though the St. Louis Cardinals aren’t expected to be shutout by the Brewers in the series, they are expected to concede at least 3 runs in this game. With this in mind, this game could turn into one of the most spectacular of the day in terms of runs scored; therefore, the pick for the St. Louis Cardinals – Milwaukee Brewers is: Over 8.5 Runs!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.