Kansas City Royals vs St. Louis Cardinals Prediction & Picks - MLB

Prediction published on 5/18/25, 10:13 AM  by Carlos Zabala | Modified on 5/18/25 at 4:40 PM in MLB Picks

After a high-scoring game, the usual low-scoring tone at Kauffman Stadium returned in Game 2 between the Cardinals and Royals. This game again ended in favor of the Cardinals by a 1-0 margin, with the only run coming from a Jordan Walker home run on one of just two hits the Cardinals gave up on the night in Kansas City. The pitching duel in Game 2 was between veteran Mikolas and Noah Cameron for the Royals. It was his second career MLB start, and although he pitched well, he lost the game. Ryan Helsley once again appears reliable as a closeout player and recorded his ninth save of the season.

The Cardinals will want to complete the sweep on Sunday afternoon, having been betting underdogs in the first two games. In Game 1, the Cardinals won at +131 odds, and in Game 2, at +102 odds. St. Louis is by far the hottest team in MLB; after a slow start, their record is now 25-20, and they have won 9 of their last 10 games.