Detroit Tigers vs St. Louis Cardinals Prediction & Picks - MLB
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by Matt Lowrimore | in MLB Picks
A full 15-game MLB slate is scheduled for Friday, which will include an interleague matchup between the Detroit Tigers (2-4) and the St. Louis Cardinals (4-2). Let’s take a look at the match statistics and predictions for this game between the Tigers and the Cardinals.
St. Louis has started the season strong, winning both of their first two series against the Tampa Bay Rays and the New York Mets. To open this series in Detroit, the Cardinals are scheduled to start Michael McGreevy. He will be making his second start of the season, and does so with an ERA of 0.00. In his first start against Tampa Bay, McGreevy went 6.0 innings and did not allow an earned run.
As for Detroit, they opened the season with two out of three wins against the San Diego Padres, but were just swept by the Arizona Diamondbacks. The Tigers are set to start Framber Valdez, who comes into his second start with an ERA of 1.50. In his first start against San Diego, Valdez went 6.0 innings and allowed two runs (one earned). As strong as he was, Detroit’s bullpen has an ERA of 5.82 so far this season, which could spell trouble for them.
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Detroit Tigers vs St. Louis Cardinals Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
11
|
0.525 | 80 | 42 | 38 |
|
25
|
0.422 | 83 | 35 | 48 |
Detroit Tigers and St. Louis Cardinals Latest Matches
2/6 (33%)
4/6 (67%)
Apr 1, 2026 - MLB
Mar 31, 2026 - MLB
Mar 30, 2026 - MLB
Mar 28, 2026 - MLB
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
2/6 (33%)
4/6 (67%)
Mar 21, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 16, 2026 - MLB Spring Training
Mar 13, 2026 - MLB Spring Training
Mar 12, 2026 - MLB Spring Training
Mar 9, 2026 - MLB Spring Training
2/6 (33%)
4/6 (67%)
Apr 1, 2026 - MLB
Mar 31, 2026 - MLB
Mar 30, 2026 - MLB
Mar 28, 2026 - MLB
Mar 27, 2026 - MLB
Mar 26, 2026 - MLB
4/6 (67%)
2/6 (33%)
Apr 1, 2026 - MLB
Mar 31, 2026 - MLB
Mar 30, 2026 - MLB
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
4/6 (67%)
2/6 (33%)
Apr 1, 2026 - MLB
Mar 31, 2026 - MLB
Mar 30, 2026 - MLB
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
3/6 (50%)
3/6 (50%)
Mar 22, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
Mar 11, 2026 - MLB Spring Training
Mar 10, 2026 - MLB Spring Training
Detroit Tigers against St. Louis Cardinals : Head to Head (H2H)
100 %
0 %
May 21, 2025 - MLB
May 20, 2025 - MLB
Apr 30, 2024 - MLB
Detroit Tigers - St. Louis Cardinals Key Points
- St. Louis is averaging 4.83 runs per game
- McGreevy has an ERA of 0.00
- Valdez has an ERA of 1.50
- Detroit is 0-3 SU in their last 3 games
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Our Detroit Tigers vs St. Louis Cardinals Prediction
Detroit is the heavy favorite in this game; however, St. Louis looks to be the best betting option. The Tigers certainly look to have a strong starting pitcher in this game, that being Valdez, but where they could have issues is their shaky bullpen. The Detroit bullpen has already posted an ERA of nearly 6.00, which has cost them several times in just the first six games.
St. Louis’ bullpen, on the other hand, has been equally as bad, but the difference is that the Cardinals’ offense has been much more efficient. Given that St. Louis simply looks to have the slight edge in starting pitching, our Detroit Tigers vs St. Louis Cardinals prediction is: St. Louis Cardinals ML.All tips are fully researched and given in good faith, but profits cannot be guaranteed.