Cleveland Guardians vs St. Louis Cardinals Prediction & Picks - MLB

Prediction published on 6/29/25, 8:22 AM  by Carlos Zabala | Modified on 6/29/25 at 3:00 PM in MLB Picks

The Cardinals haven't lost a series since the second week of June, and after beating the Guardians 5-0 in Game 1 of their series in Cleveland, they showed their ability to hit in rallies to close out a 5-run deficit in Game 2, with the Cards scoring 5 runs of their own in the top of the sixth inning. In that key inning of Saturday's Guards-Cards game, Gorman, Scott, Donovan, and Winn all managed to drive in runs. The Cardinals won 6-9 as the betting underdogs, and Helsley closed the door with his 16th save of the season.

The Cardinals-Guardians series finale on Sunday will be played at noon in Cleveland, the first game of the Sunday schedule. Matthew Liberatore will be the Cards' starting pitcher with a 3.96 ERA, and Logan Allen will be the Guardians' starter with a 5-5 record and a 4.25 ERA.