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by Tyler Doty in ATP US Open Picks
Jannik Sinner (No. 1) faces Lorenzo Musetti (No. 10) in the quarterfinals of the US Open. The ‘Ace-sinner’ continues his unstoppable run in this Grand Slam and leaves no room for doubt, despite questions about his title aspirations after withdrawing from the Cincinnati Masters final due to injury. As proof of his outstanding form, he easily defeated Alexander Bublik with a crushing 6-1 victory.
Musetti, meanwhile, is still in the process of establishing himself in the top division, although he has unfinished business: he has not won a title since 2022 (in Naples). Although he had gone unnoticed in Toronto (second round) and Cincinnati (debut and farewell), the Italian player shook off those ups and downs and comes off a victory over Jaume Munar, 6-3, 6-0, and 6-1 in sets, in just one hour and 38 minutes.
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Jannik Sinner vs Lorenzo Musetti Form
Jannik Sinner and Lorenzo Musetti Latest Matches
5/6 (83%)
1/6 (17%)
Sep 1, 2025 - ATP US Open
Aug 30, 2025 - ATP US Open
Aug 28, 2025 - ATP US Open
Aug 26, 2025 - ATP US Open
Aug 18, 2025 - ATP Cincinnati Open
Aug 16, 2025 - ATP Cincinnati Open
3/6 (50%)
3/6 (50%)
Sep 1, 2025 - ATP US Open
Aug 30, 2025 - ATP US Open
Aug 28, 2025 - ATP US Open
Aug 26, 2025 - ATP US Open
Aug 9, 2025 - ATP Cincinnati Open
Jul 31, 2025 - ATP Toronto
Jannik Sinner against Lorenzo Musetti : Head to Head (H2H)
100 %
0 %
Apr 21, 2023 - ATP Barcelona
Apr 14, 2023 - ATP Monte Carlo Masters
Oct 20, 2021 - ATP European Open
Jannik Sinner - Lorenzo Musetti Key Points
- The last time they played was in Monte Carlo in 2023: Sinner celebrated with a double 6-2 victory.
- Prior to that, they clashed in Antwerp in 2023: Musetti didn't put up much of a fight either and lost 5-7, 2-6.
- Jannik Sinner is coming off a victory with eight aces and eight service breaks (he didn't give up anything).
- Lorenzo Musetti is coming off a victory with seven aces and seven service breaks (nothing against him).
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Our Jannik Sinner vs Lorenzo Musetti Prediction
The books have Sinner as the clear favorite, given his dominance in this tournament and in head-to-head matches. That gives him absolute backing.
However, Musetti has shown that he has what it takes to put up a fight against any opponent and needs to make his mark in the top flight.
Based on this analysis, our prediction fo Jannik Sinner vs Lorenzo Musetti is: Sinner in straight sets!
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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