Houston Astros vs Seattle Mariners Prediction & Picks - MLB

Prediction published on 5/14/26, 10:16 AM  by Carlos Zabala | Modified on 5/14/26 at 6:35 PM in MLB Picks

The first game of the series between the Mariners and Astros at Daikin Park was won by Seattle 3-1 with a home run by Julio Rodríguez. Miller started the second game of the series for the Mariners, and McCullers for the Astros. Coincidentally, both pitched 5.1 innings on Wednesday, but it was the Astros who prevailed, winning 4-3 with a walk-off hit by Cole in the tenth inning. This ended the Mariners' four-game losing streak.

The Mariners will certainly be going all out in the final game of the series. Arozarena, Raley, and Crawford each had a multi-hit game in Wednesday's loss, which was a fleeting offensive resurgence. However, it's concerning that last season's home run leader is having such a forgettable 2026. Cal Raleigh recently snapped a bizarre 0-for-38 hitting streak, but in Game 2 of the series, he went 0-for-4 with two strikeouts, and his batting average remains below .166.

As for the Astros, Yordan Alvarez, with 13 home runs this season, went 1-for-3 on Wednesday and maintains his average above .300. The skilled Altuve hit a key sacrifice fly with two strikes to put the Astros ahead with one minute left in the game. Walker hit his tenth home run of the season.