Houston Astros vs Seattle Mariners Prediction & Picks - MLB
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The Houston Astros and the Seattle Mariners meet at Daikin Park on Wednesday night in the final game of a series that has been dominated by a rapidly improving Seattle side.
After edging the first matchup of the series 3-1, the Mariners produced a superb game two display to trounce Houston 10-2. Those two victories have moved Seattle to 21-22 for the season, a record that puts them hot on the heels of the Oakland Athletics in the AL West.
It has been an utterly dismal season so far for the Astros; their current 16-27 record is the joint worst in the entire American League. Home form has been an especially big issue for the Astros, and they have now lost ten of their last 12 matchups at Daikin Park.
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Houston Astros vs Seattle Mariners Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
12
|
0.504 | 119 | 60 | 59 |
|
24
|
0.471 | 119 | 56 | 63 |
Houston Astros and Seattle Mariners Latest Matches
1/6 (17%)
5/6 (83%)
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2/6 (33%)
4/6 (67%)
May 12, 2026 - MLB
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3/6 (50%)
3/6 (50%)
May 10, 2026 - MLB
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4/6 (67%)
2/6 (33%)
May 12, 2026 - MLB
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2/6 (33%)
4/6 (67%)
May 6, 2026 - MLB
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May 2, 2026 - MLB
May 1, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 12, 2026 - MLB
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Houston Astros against Seattle Mariners : Head to Head (H2H)
0 %
100 %
May 12, 2026 - MLB
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Houston Astros - Seattle Mariners Key Points
- Seattle have won 5 of their last 7 road games
- Houston have lost 10 of their last 12 home games
- The Astros are on a 4 game losing streak
- seattle have won their last 9 matches against Houston
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Our Houston Astros vs Seattle Mariners Prediction
The bookies give Houston the slight edge in this one, but their recent displays do little to suggest they can end their four game losing run.
The Mariners are far from the finished article, but they have been steadily improving in recent weeks, and as they showed in game two, they have more than enough offensive firepower to cause plenty of problems for the Astros.
Not only are we tipping Seattle to win, but we think they will do so comfortably and easily beat the -1 spread.
Our prediction for Houston Astros vs Seattle Mariners is: Mariners (-1) to win.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
