San Jose Earthquakes vs Saint Louis City SC Prediction & Picks - Major League Soccer

Prediction published on 9/20/25, 7:07 PM  by Edgar Jibran | Modified on 9/21/25 at 3:14 AM in Major League Soccer Picks

MLS has started to define the teams that will qualify for the playoffs, and the Western Conference is already delivering some interesting surprises. Teams like San Jose Earthquakes are still competing for Play-In spots, while some others like St. Louis City are practically eliminated from the competition. Given this context, the clash between these teams next Saturday night is expected to be one of the most entertaining games of the weekend.

For their part, even though San Jose Earthquakes are still competing for Play-In spots, they’ll jump into the pitch for this game on a two-game losing streak, having conceded three or more goals per game. Additionally, it’s highly relevant to note that they haven’t been able to keep a clean sheet since their 1-0 away victory over LA Galaxy on May 28th, making the Earthquakes one of the least effective defenses in the league.

Meanwhile, St. Louis City hasn’t been able to become a competitive team despite being one of the newest franchises to join the MLS. They’ll most likely face their second consecutive season without qualifying for the playoffs, standing out as one of the worst defenses in the Western Conference after conceding 51 goals through the season. Despite this poor performance, they ended a four-game winless streak with their most recent away victory over CF Montreal (2-0).