Pittsburgh Pirates vs San Francisco Giants Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Lou Aguila | in MLB Picks
The San Francisco Giants and the Pittsburgh Pirates are heading into a rubber match on Wednesday at PNC Park after splitting the first two games of their series.
The Giants opened the betting lines as the favorites at -148 on FanDuel. On Tuesday, San Francisco is coming off a convincing 8-1 win over the Pirates. Willy Adames, Patrick Bailey and Christian Kross each drove two RBIs, while Rafael Davers and Jerar Encarnacion each chipped in one RBIs. The Giants also benefited from an impeccable mound performance by Logan Webb, who surrendered one earned run with 10 strikeouts over six innings.
The Pirates are listed as +126 underdogs on FanDuel following their heavy loss to the Giants. Pittsburgh came into Tuesday night’s ballgame with the Giants, averaging almost 8 runs per game on a .280 batting average in the past five games. Unfortunately, the Pirates' offense was a non-factor with All-Star slugger Bryan Reynolds driving the lone run for his team in the game.
Limited Offer. Currently at FanDuel
Pittsburgh Pirates vs San Francisco Giants Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
16
|
0.5 | 162 | 81 | 81 |
|
26
|
0.438 | 162 | 71 | 91 |
Pittsburgh Pirates and San Francisco Giants Latest Matches
4/6 (67%)
2/6 (33%)
Aug 5, 2025 - MLB
Aug 4, 2025 - MLB
Aug 2, 2025 - MLB
Jul 30, 2025 - MLB
Jul 29, 2025 - MLB
Jul 28, 2025 - MLB
4/6 (67%)
2/6 (33%)
Aug 5, 2025 - MLB
Aug 4, 2025 - MLB
Jul 27, 2025 - MLB
Jul 26, 2025 - MLB
Jul 25, 2025 - MLB
Jul 23, 2025 - MLB
3/6 (50%)
3/6 (50%)
Aug 2, 2025 - MLB
Jul 30, 2025 - MLB
Jul 29, 2025 - MLB
Jul 28, 2025 - MLB
Jul 12, 2025 - MLB
Jul 11, 2025 - MLB
2/6 (33%)
4/6 (67%)
Aug 5, 2025 - MLB
Aug 4, 2025 - MLB
Aug 3, 2025 - MLB
Jul 30, 2025 - MLB
Jul 29, 2025 - MLB
Jul 28, 2025 - MLB
0/6 (0%)
6/6 (100%)
Jul 30, 2025 - MLB
Jul 29, 2025 - MLB
Jul 28, 2025 - MLB
Jul 26, 2025 - MLB
Jul 25, 2025 - MLB
Jul 13, 2025 - MLB
3/6 (50%)
3/6 (50%)
Aug 5, 2025 - MLB
Aug 4, 2025 - MLB
Aug 3, 2025 - MLB
Jul 23, 2025 - MLB
Jul 20, 2025 - MLB
Jul 19, 2025 - MLB
Pittsburgh Pirates against San Francisco Giants : Head to Head (H2H)
83 %
17 %
Aug 5, 2025 - MLB
Aug 4, 2025 - MLB
Jul 30, 2025 - MLB
Jul 29, 2025 - MLB
Jul 28, 2025 - MLB
May 21, 2024 - MLB
Pittsburgh Pirates - San Francisco Giants Key Points
- Pittsburgh is 6-2 SU in its last 8 games at home.
- Pittsburgh is 10-4 SU in its last 14 games.
- San Francisco is 5-14 SU in its last 19 games.
- San Francisco is 1-4 SU in its last 5 games against Pittsburgh.
Limited Offer. Currently at FanDuel
Our Pittsburgh Pirates vs San Francisco Giants Prediction
Tuesday’s win ended the Giants’ four-game losing streak against the Pirates. San Francisco has a solid chance to establish a winning streak with Robbie Ray starting in the series finale. Ray (2-3, 3.45 ERA in the last 5 starts) will be pitching against the Pirates for the first time since 2019. In his last start vs. the Mets, Ray yielded one run with 6 strikeouts to help the Giants secure a 4-3 win over the Mets on Aug 1.
The Pirates will send Andrew Heaney (2-3, 5.73 ERA in his last 5). Heaney allowed 3 runs in 3.1 innings in the Pirates 16-17 loss to the Colorado Rockies on August 1. Pittsburgh is 6-2 SU in its last 8 games at home and 4-1 in their last 5 vs. the Giants.
I see a ton of value in betting on Pittsburgh at the +126 moneyline. I feel the Pirates will put up a better effort in the series finale after the embarrassment they suffered at home on Tuesday. This team’s offense has been so explosive in the past five games (7.7 runs per game) that they can rip a game apart with just one massive rally. Although giving up an 8.52 ERA in the last five games is certainly worrying, I believe their starter, Andrew Heaney, will deliver decent numbers on the mound on Tuesday, putting his team in a position to win.
Our betting prediction for the Pittsburgh Pirates vs. the San Francisco Giants: the Pirates will win.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
