Pittsburgh Pirates vs San Francisco Giants Prediction & Picks - MLB

Prediction published on 8/5/25, 2:53 PM  by Lou Aguila | Modified on 8/5/25 at 11:17 PM in MLB Picks

The Pittsburgh Pirates offer a lot of value for bold bettors who will wager on them as +129 underdogs against the San Francisco Giants in Game 2 of their series on Tuesday at PNC Park.

The Pirates registered their second straight win after rallying past the Giants 5-2 in the series opener. Pittsburgh overcame a 1-4 deficit as Jack Suwinski ignited a late comeback run with a two-run homer in the 7th inning. In the 9th inning, catcher Joey Bart leveled the score at 4-4 with an RBI single, while Isaiah Kiner-Falefa drove in the game-winning run with a fielder's choice. While the Pirates are still last in the NL West with a 49-64 record, the win improved their record to 10-3 in their last 13 games.

The Giants dropped to 4-12 after the All-Star break following Monday’s defeat to the Pirates. The loss further exposed San Francisco’s inability to win the majority of tight ballgames this season. The Giants ' offense is in good shape with an average of 5.2 runs per game. They are just playing a team with a more explosive offense, as the Pirates average 7.3 runs per game on a .263 batting average.