Philadelphia Phillies vs San Francisco Giants Prediction & Picks - MLB

USA - MLB

Philadelphia Phillies
4/29/26 18:10
San Francisco Giants

Prediction:

 

Philadelphia to win

-150
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 by Bill Christy | in MLB Picks

The Philadelphia Phillies (10-19) have been arguably the most underachieving team to this point in the season. The team finally decided to make a move this week and fired manager Rob Thomson and elevated Don Mattingly to the head role. Their recent 10-game losing streak was likely the breaking point and brought Thomson’s run as manager to an end.

In his 1st game as manager, Mattingly saw the Phillies play with some rejuvenation and picked up a 7-0 win over the San Francisco Giants (13-16). Trea Turner and Bryce Harper combined to go 6-9 with 2 RBIs and 3 runs scored. Jesus Luzardo was in command on the mound and went 7 innings of scoreless work while striking out 8. Now, they will look to one of their top pitchers to keep this momentum going against the Giants.

Cristopher Sanchez will be starting tonight and has probably been the most consistent player of all the Phillies this season. Despite getting roughed up in his last outing against the Cubs, he is still carrying a solid 2.94 ERA. He will be countered by San Francisco’s Logan Webb. Webb is 2-3 on the year and has a 4.86 ERA. He has been going between 6 and 7 innings consistently, but teams always seem to find a way to put up 3-4 runs on him.

Philadelphia Phillies vs San Francisco Giants Form

Table

Teams Pts P W L
6 Philadelphia Phillies
0.554 83 46 37
28 San Francisco Giants
0.415 82 34 48

Philadelphia Phillies and San Francisco Giants Latest Matches

Philadelphia Phillies
Philadelphia Phillies Latest matches
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2026 - MLB

Philadelphia Phillies
7 :  0
San Francisco Giants

Apr 26, 2026 - MLB

Atlanta Braves
6 :  2
Philadelphia Phillies

Apr 25, 2026 - MLB

Atlanta Braves
5 :  8
Philadelphia Phillies

Apr 24, 2026 - MLB

Atlanta Braves
5 :  3
Philadelphia Phillies

Apr 23, 2026 - MLB

Chicago Cubs
8 :  7
Philadelphia Phillies

Apr 22, 2026 - MLB

Chicago Cubs
7 :  2
Philadelphia Phillies
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 28, 2026 - MLB

Philadelphia Phillies
7 :  0
San Francisco Giants

Apr 19, 2026 - MLB

Philadelphia Phillies
2 :  4
Atlanta Braves

Apr 18, 2026 - MLB

Philadelphia Phillies
1 :  3
Atlanta Braves

Apr 17, 2026 - MLB

Philadelphia Phillies
0 :  9
Atlanta Braves

Apr 15, 2026 - MLB

Philadelphia Phillies
2 :  11
Chicago Cubs

Apr 14, 2026 - MLB

Philadelphia Phillies
4 :  10
Chicago Cubs
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 26, 2026 - MLB

Atlanta Braves
6 :  2
Philadelphia Phillies

Apr 25, 2026 - MLB

Atlanta Braves
5 :  8
Philadelphia Phillies

Apr 24, 2026 - MLB

Atlanta Braves
5 :  3
Philadelphia Phillies

Apr 23, 2026 - MLB

Chicago Cubs
8 :  7
Philadelphia Phillies

Apr 22, 2026 - MLB

Chicago Cubs
7 :  2
Philadelphia Phillies

Apr 21, 2026 - MLB

Chicago Cubs
7 :  4
Philadelphia Phillies
San Francisco Giants
San Francisco Giants Latest matches
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 28, 2026 - MLB

Philadelphia Phillies
7 :  0
San Francisco Giants

Apr 26, 2026 - MLB

San Francisco Giants
6 :  3
Miami Marlins

Apr 25, 2026 - MLB

San Francisco Giants
6 :  2
Miami Marlins

Apr 24, 2026 - MLB

San Francisco Giants
4 :  9
Miami Marlins

Apr 23, 2026 - MLB

San Francisco Giants
0 :  3
Los Angeles Dodgers

Apr 22, 2026 - MLB

San Francisco Giants
3 :  0
Los Angeles Dodgers
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 26, 2026 - MLB

San Francisco Giants
6 :  3
Miami Marlins

Apr 25, 2026 - MLB

San Francisco Giants
6 :  2
Miami Marlins

Apr 24, 2026 - MLB

San Francisco Giants
4 :  9
Miami Marlins

Apr 23, 2026 - MLB

San Francisco Giants
0 :  3
Los Angeles Dodgers

Apr 22, 2026 - MLB

San Francisco Giants
3 :  0
Los Angeles Dodgers

Apr 21, 2026 - MLB

San Francisco Giants
3 :  1
Los Angeles Dodgers
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 28, 2026 - MLB

Philadelphia Phillies
7 :  0
San Francisco Giants

Apr 19, 2026 - MLB

Washington Nationals
3 :  0
San Francisco Giants

Apr 18, 2026 - MLB

Washington Nationals
6 :  7
San Francisco Giants

Apr 17, 2026 - MLB

Washington Nationals
5 :  10
San Francisco Giants

Apr 16, 2026 - MLB

Cincinnati Reds
0 :  3
San Francisco Giants

Apr 15, 2026 - MLB

Cincinnati Reds
8 :  3
San Francisco Giants

Philadelphia Phillies against San Francisco Giants : Head to Head (H2H)

Philadelphia Phillies

50 %

San Francisco Giants

50 %

Apr 28, 2026 - MLB

Philadelphia Phillies
7 :  0
San Francisco Giants

Apr 8, 2026 - MLB

San Francisco Giants
5 :  0
Philadelphia Phillies

Apr 7, 2026 - MLB

San Francisco Giants
6 :  0
Philadelphia Phillies

Apr 6, 2026 - MLB

San Francisco Giants
4 :  6
Philadelphia Phillies

Jul 9, 2025 - MLB

San Francisco Giants
0 :  13
Philadelphia Phillies

Jul 8, 2025 - MLB

San Francisco Giants
4 :  3
Philadelphia Phillies

Philadelphia Phillies - San Francisco Giants Key Points

  1. San Francisco is 2-7 SU in its last 9 games when playing on the road against Philadelphia.
  2. San Francisco is 8-19 SU in its last 27 games when playing on the road against Philadelphia.
  3. Philadelphia is 4-1 SU in its last 5 games played on a Wednesday when playing at home.
  4. Philadelphia is 10-3 SU in its last 13 games when playing at home against San Francisco.

Our Philadelphia Phillies vs San Francisco Giants Prediction

The Phillies have the talent to be one of the better teams in baseball. Something seemed off about the team all offseason and that bled into the regular season. Not to say Thomson was the only problem, but this team seemed rejuvenated after he was let go and Mattingly stepped in. We expect Sanchez to bounce back from his bad start against the Cubs and give the Phillies a solid 6-7 innings of work here tonight and pick up the win.

Our prediction for Philadelphia Phillies vs San Francisco Giants: Philadelphia to win

Prediction:

 

Philadelphia to win

-150
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Philadelphia Phillies vs San Francisco Giants Picks