Philadelphia Phillies vs San Francisco Giants Prediction & Picks - MLB

Prediction published on 4/17/25, 12:14 PM  by Carlos Zabala | Modified on 2/11/26 at 8:39 AM in MLB Picks

The Giants have been the Phillies' toughest opponent in 2025. In the four-game series that concludes Thursday, the Giants took Game 3, winning 11-4, with an early attack on veteran Nola, driving in four runs in the first inning. After the Phillies took Game 2, Wednesday's game was the second game of the series in which the Giants scored 10 or more runs.

Nola would ultimately lose, earning his fourth L of the season, a stat that should concern the Phillies. Meanwhile, the Giants managed to score 11 runs without a home run. The Giants' bats, Lee of Korea and Flores of Venezuela, had already gotten off to a good start, and Yastrzemski joined the party, connecting on his fourth and fifth doubles of the season against the Phillies, both in the seventh inning, where he hit twice.

For the Phillies, Harper hit his 4th home run of the season to temporarily tie the game at 4-4 in the 4th inning. Nola allowed 6 ER, but reliever Joe Ross ended up giving the game to the Giants by allowing 4 more.