Houston Astros vs San Francisco Giants Prediction & Picks - MLB

USA - MLB

Houston Astros
4/1/25 20:10
San Francisco Giants

Prediction:

 

Giants ML.

-116
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 by Carlos Zabala in MLB Picks

With a good team effort, good pitching, and a particularly good game by Wilmer Flores, who with a hit and his 3rd HR of the season drove in 4 before the sixth inning, the Giants won the first of the series against the Astros, who still have not managed to make more than 3 runs this season.

For the Giants, ace Logan Webb returns for his second start of the season in Game 2. Webb pitched on his team's Opening Day, and although the Giants ultimately won 6-4 against the Reds, Webb didn't take the W after allowing three runs in 5.0 innings with five strikeouts and three runs.

Bookmakers predict a close game in the second game of the series between the Giants and Astros, with the visiting team starting as the favorite with odds around -120. The Astros still haven't found their home run rhythm, having only hit one before the start of the series against the Giants, leading the MLB in that category. Yordan Alvarez hasn't hit more than .200 in the first week of action.

Houston Astros vs San Francisco Giants Form

Table

Teams Pts P W L
12 Houston Astros
0.537 162 87 75
16 San Francisco Giants
0.5 162 81 81

Houston Astros and San Francisco Giants Latest Matches

Houston Astros
Houston Astros Latest matches
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Mar 31, 2025 - MLB

Houston Astros
2 :  7
San Francisco Giants

Mar 29, 2025 - MLB

Houston Astros
2 :  1
New York Mets

Mar 28, 2025 - MLB

Houston Astros
1 :  3
New York Mets

Mar 27, 2025 - MLB

Houston Astros
3 :  1
New York Mets

Oct 2, 2024 - MLB

Houston Astros
2 :  5
Detroit Tigers

Oct 1, 2024 - MLB

Houston Astros
1 :  3
Detroit Tigers
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Mar 31, 2025 - MLB

Houston Astros
2 :  7
San Francisco Giants

Mar 29, 2025 - MLB

Houston Astros
2 :  1
New York Mets

Mar 28, 2025 - MLB

Houston Astros
1 :  3
New York Mets

Mar 27, 2025 - MLB

Houston Astros
3 :  1
New York Mets

Oct 2, 2024 - MLB

Houston Astros
2 :  5
Detroit Tigers

Oct 1, 2024 - MLB

Houston Astros
1 :  3
Detroit Tigers
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 28, 2024 - MLB

Cleveland Guardians
3 :  4
Houston Astros

Sep 18, 2024 - MLB

San Diego Padres
4 :  0
Houston Astros

Sep 17, 2024 - MLB

San Diego Padres
3 :  4
Houston Astros

Sep 16, 2024 - MLB

San Diego Padres
3 :  1
Houston Astros

Sep 15, 2024 - MLB

Los Angeles Angels
4 :  6
Houston Astros

Sep 14, 2024 - MLB

Los Angeles Angels
3 :  5
Houston Astros
San Francisco Giants
San Francisco Giants Latest matches
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Mar 31, 2025 - MLB

Houston Astros
2 :  7
San Francisco Giants

Mar 30, 2025 - MLB

Cincinnati Reds
3 :  6
San Francisco Giants

Mar 29, 2025 - MLB

Cincinnati Reds
3 :  2
San Francisco Giants

Mar 27, 2025 - MLB

Cincinnati Reds
4 :  6
San Francisco Giants

Sep 23, 2024 - MLB

Arizona Diamondbacks
3 :  6
San Francisco Giants

Sep 20, 2024 - MLB

Kansas City Royals
1 :  2
San Francisco Giants
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 15, 2024 - MLB

San Francisco Giants
3 :  4
San Diego Padres

Sep 5, 2024 - MLB

San Francisco Giants
3 :  2
Arizona Diamondbacks

Sep 3, 2024 - MLB

San Francisco Giants
7 :  8
Arizona Diamondbacks

Aug 31, 2024 - MLB

San Francisco Giants
3 :  4
Miami Marlins

Aug 30, 2024 - MLB

San Francisco Giants
3 :  1
Miami Marlins

Aug 21, 2024 - MLB

San Francisco Giants
2 :  6
Chicago White Sox
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Mar 31, 2025 - MLB

Houston Astros
2 :  7
San Francisco Giants

Mar 30, 2025 - MLB

Cincinnati Reds
3 :  6
San Francisco Giants

Mar 29, 2025 - MLB

Cincinnati Reds
3 :  2
San Francisco Giants

Mar 27, 2025 - MLB

Cincinnati Reds
4 :  6
San Francisco Giants

Sep 23, 2024 - MLB

Arizona Diamondbacks
3 :  6
San Francisco Giants

Sep 20, 2024 - MLB

Kansas City Royals
1 :  2
San Francisco Giants

Houston Astros against San Francisco Giants : Head to Head (H2H)

Houston Astros

25 %

San Francisco Giants

75 %

Mar 31, 2025 - MLB

Houston Astros
2 :  7
San Francisco Giants

Jun 12, 2024 - MLB

San Francisco Giants
5 :  3
Houston Astros

Jun 11, 2024 - MLB

San Francisco Giants
1 :  3
Houston Astros

Jun 10, 2024 - MLB

San Francisco Giants
4 :  3
Houston Astros

Houston Astros - San Francisco Giants Key Points

  1. Logan Webb had a 3.47 ERA in 2024 with the Giants
  2. Giants won their last two series against the Astros
  3. Giants got more than 4 BBs in their win against the Astros
  4. The Giants' 2024 road record was 16-12, and they were the betting favorites in 2024

Our Houston Astros vs San Francisco Giants Prediction

It's happened before that the Astros have had a slow start to the season, but they still emerged victorious in their opening series against the Mets. For the Astros, Game 2 will be pitched by Hayden Wesneski, who last pitched in spring training against the Blue Jays and allowed 3 runs in 3 innings. Despite a line drive recently hitting his foot, everything seems to be going well for his start against the Giants' ace. Our prediction for Giants vs Astros is: Giants ML.

Prediction:

 

Giants ML.

-116
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Astros vs San Francisco Giants Picks