Detroit Tigers vs San Francisco Giants Prediction & Picks - MLB

Prediction published on 5/26/25, 9:32 AM  by Carlos Zabala | Modified on 5/26/25 at 3:35 PM in MLB Picks

The Tigers lost the series at Comerica Park but salvaged the final game by winning 5-0 over the Guardians. They will stay in Detroit to host the Giants after noon on Monday in a highly evenly matched betting game.

With a pitcher like Skubal on your side, scoring a couple of runs is almost enough to win. The reigning Cy Young Award winner will once again compete for the award for the best pitcher in the American League, this time against the Yankees' Max Fried. His last start was simply epic. Skubal pitched his first complete game, recording the most strikeouts in MLB history for a pitcher throwing a complete game in fewer than 100 pitches. His presence alone made the Tigers -310 favorites in the betting, and they won thanks to Skubal, but also thanks to the contribution of McKinstry, who hit his third home run of the season.

That same day, the Giants won their series against the Nats at Nationals Park, beating them 3-2 in the last game. Robbie Ray had a good start, winning in a low-hit game: 10 between the two teams.