Pittsburgh Pirates vs San Diego Padres Prediction & Picks - MLB

USA - MLB

Pittsburgh Pirates
5/2/25 18:40
San Diego Padres

Prediction:

 

Padres -1.5 Runs

+120
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 by Lou Aguila | in MLB Picks

The Pittsburgh Pirates will play host to the San Diego Padres starting Friday at PNC Park.

The Pirates dropped to 12-20 after winning just one match in a three-game series with the Chicago Cubs this week. As usual, Pittsburgh struggled anew on the mound, allowing the Cubs to outscore them 9-0 in Game 1 and 8-3 in Game 3. The Pirates carry the 10th worst ERA in baseball at 4.23 and post a .224 batting average – the fifth worst in the MLB.

The Padres ended their four-game win drought with back-to-back victories over division rivals the San Francisco Giants. San Diego, which is averaging 3.1 runs per game over its last five games, outscored the Giants by relying heavily on its pitching staff, especially its vaunted bullpen, which boasts a 1.77 ERA.

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Pittsburgh Pirates vs San Diego Padres Form

Table

Teams Pts P W L
7 San Diego Padres
0.556 162 90 72
26 Pittsburgh Pirates
0.438 162 71 91

Pittsburgh Pirates and San Diego Padres Latest Matches

Pittsburgh Pirates
Pittsburgh Pirates Latest matches
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 1, 2025 - MLB

Pittsburgh Pirates
3 :  8
Chicago Cubs

Apr 30, 2025 - MLB

Pittsburgh Pirates
4 :  3
Chicago Cubs

Apr 29, 2025 - MLB

Pittsburgh Pirates
0 :  9
Chicago Cubs

Apr 26, 2025 - MLB

Los Angeles Dodgers
8 :  4
Pittsburgh Pirates

Apr 25, 2025 - MLB

Los Angeles Dodgers
0 :  3
Pittsburgh Pirates

Apr 24, 2025 - MLB

Los Angeles Angels
4 :  3
Pittsburgh Pirates
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 1, 2025 - MLB

Pittsburgh Pirates
3 :  8
Chicago Cubs

Apr 30, 2025 - MLB

Pittsburgh Pirates
4 :  3
Chicago Cubs

Apr 29, 2025 - MLB

Pittsburgh Pirates
0 :  9
Chicago Cubs

Apr 20, 2025 - MLB

Pittsburgh Pirates
4 :  5
Cleveland Guardians

Apr 19, 2025 - MLB

Pittsburgh Pirates
0 :  3
Cleveland Guardians

Apr 18, 2025 - MLB

Pittsburgh Pirates
7 :  10
Cleveland Guardians
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 26, 2025 - MLB

Los Angeles Dodgers
8 :  4
Pittsburgh Pirates

Apr 25, 2025 - MLB

Los Angeles Dodgers
0 :  3
Pittsburgh Pirates

Apr 24, 2025 - MLB

Los Angeles Angels
4 :  3
Pittsburgh Pirates

Apr 23, 2025 - MLB

Los Angeles Angels
0 :  3
Pittsburgh Pirates

Apr 13, 2025 - MLB

Cincinnati Reds
4 :  0
Pittsburgh Pirates

Apr 12, 2025 - MLB

Cincinnati Reds
5 :  2
Pittsburgh Pirates
San Diego Padres
San Diego Padres Latest matches
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 30, 2025 - MLB

San Diego Padres
5 :  3
San Francisco Giants

Apr 29, 2025 - MLB

San Diego Padres
7 :  4
San Francisco Giants

Apr 27, 2025 - MLB

San Diego Padres
2 :  4
Tampa Bay Rays

Apr 25, 2025 - MLB

San Diego Padres
0 :  1
Tampa Bay Rays

Apr 23, 2025 - MLB

Detroit Tigers
6 :  0
San Diego Padres

Apr 22, 2025 - MLB

Detroit Tigers
0 :  2
San Diego Padres
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 30, 2025 - MLB

San Diego Padres
5 :  3
San Francisco Giants

Apr 29, 2025 - MLB

San Diego Padres
7 :  4
San Francisco Giants

Apr 27, 2025 - MLB

San Diego Padres
2 :  4
Tampa Bay Rays

Apr 25, 2025 - MLB

San Diego Padres
0 :  1
Tampa Bay Rays

Apr 16, 2025 - MLB

San Diego Padres
4 :  2
Chicago Cubs

Apr 14, 2025 - MLB

San Diego Padres
10 :  4
Chicago Cubs
W L L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 23, 2025 - MLB

Detroit Tigers
6 :  0
San Diego Padres

Apr 22, 2025 - MLB

Detroit Tigers
0 :  2
San Diego Padres

Apr 21, 2025 - MLB

Detroit Tigers
6 :  4
San Diego Padres

Apr 19, 2025 - MLB

Houston Astros
3 :  2
San Diego Padres

Apr 18, 2025 - MLB

Houston Astros
6 :  4
San Diego Padres

Apr 9, 2025 - MLB

Athletics
1 :  2
San Diego Padres

Pittsburgh Pirates against San Diego Padres : Head to Head (H2H)

Pittsburgh Pirates

0 %

San Diego Padres

100 %

Aug 14, 2024 - MLB

San Diego Padres
8 :  2
Pittsburgh Pirates

Aug 13, 2024 - MLB

San Diego Padres
3 :  0
Pittsburgh Pirates

Aug 12, 2024 - MLB

San Diego Padres
2 :  1
Pittsburgh Pirates

Aug 8, 2024 - MLB

Pittsburgh Pirates
6 :  7
San Diego Padres

Aug 7, 2024 - MLB

Pittsburgh Pirates
8 :  9
San Diego Padres

Aug 6, 2024 - MLB

Pittsburgh Pirates
0 :  6
San Diego Padres

Pittsburgh Pirates - San Diego Padres Key Points

  1. San Diego is 2-4 SU in its last 6 games.
  2. San Diego is 6-0 SU in its last 6 games against Pittsburgh.
  3. Pittsburgh is 1-4 SU in its last 5 games.
  4. Pittsburgh is 1-5 SU in its last 6 games at home.
Up to $250 to bet on Pittsburgh Pirates - San Diego Padres! 

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Our Pittsburgh Pirates vs San Diego Padres Prediction

The Padres are sending Dylan Cease (5.68 ERA) to the mound in Game 1 vs. the Pirates. Cease, who surrendered two earned runs in his last three starts, will match up against Pirates starter Mitch Keller (4.50 ERA). The Padres’ offense might be subpar at best this season, but I still like their chances against a much worse run-scoring team in the Pirates, who are scoring 2.7 runs per game in their last five assignments. Moreover, Keller squandered eight runs the last time he started against the Padres on August 14, 2014. Our betting prediction for the San Diego Padres vs. Pittsburgh Pirates: Padres -1.5 Runs

Prediction:

 

Padres -1.5 Runs

+120
$250 offered for betting!

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Pittsburgh Pirates vs San Diego Padres Picks