Philadelphia Phillies vs San Diego Padres Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Matt Lowrimore in MLB Picks
A full 15-game MLB slate is scheduled for Wednesday, which includes a National League matchup between the Philadelphia Phillies and the San Diego Padres. Let’s take a look at the match statistics and predictions for this game between the Phillies and the Padres.
San Diego enters this game with a record of 32-27 and is in third place in the NL West division. The Padres lost Game 1 of this series and will look to bounce back in Game 2 by starting Walker Buehler. He has a record of 3-3 and an ERA of 4.88. To go along with his subpar ERA, Buehler has been terrible on the road this season, which gives the Phillies a good chance to win Game 2.
As for Philadelphia, they enter this game with a record of 31-29 and are in second place in the NL East. The Phillies are scheduled to start Cristopher Sanches, who has a record of 6-2 and an ERA of 1.47. The good news for the Phillies is that Sanchez has been almost unhittable when pitching at home, strengthening the chances for Philadelphia to win.
Limited Offer. Currently at DraftKings
Philadelphia Phillies vs San Diego Padres Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
7
|
0.542 | 59 | 32 | 27 |
|
14
|
0.517 | 60 | 31 | 29 |
Philadelphia Phillies and San Diego Padres Latest Matches
4/6 (67%)
2/6 (33%)
Jun 2, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
2/6 (33%)
4/6 (67%)
Jun 2, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
May 20, 2026 - MLB
May 19, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
May 25, 2026 - MLB
1/6 (17%)
5/6 (83%)
Jun 2, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
2/6 (33%)
4/6 (67%)
May 27, 2026 - MLB
May 26, 2026 - MLB
May 25, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
3/6 (50%)
3/6 (50%)
Jun 2, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
Philadelphia Phillies against San Diego Padres : Head to Head (H2H)
83 %
17 %
Jun 2, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
May 25, 2026 - MLB
Jul 13, 2025 - MLB
Jul 12, 2025 - MLB
Philadelphia Phillies - San Diego Padres Key Points
- Walker Buehler has an ERA of 4.88 this season
- Walker Buehler has an ERA of 8.04 on the road this season
- Cristopher Sanchez has an ERA of 1.47 this season
- Cristopher Sanchez has an ERA of 0.85 this season
Limited Offer. Currently at DraftKings
Our Philadelphia Phillies vs San Diego Padres Prediction
The Phillies are the heavy favorite in this game; however, they still look to be the best betting option. Looking back at the starting pitchers’ home/away splits, we see that Buehler has made four starts, having allowed 14 earned runs over 15.2 innings. Sanchez, on the other hand, has made eight home starts, having allowed eight runs (five earned) over 53.0 innings.
Both the Phillies and the Padres are near the bottom of the league in terms of runs scored per game; therefore, given the clear advantage they have on the mound with Sanchez, our Philadelphia Phillies vs San Diego Padres prediction is: Philadelphia Phillies ML.A 2026 WC Welcome Bonus for Philadelphia Phillies vs San Diego Padres!

Looking to place a bet on Philadelphia Phillies vs San Diego Padres? For this MLB match and throughout the World Cup, DraftKings will treat you to an exclusive offer: $200 in bonus bets, no promo code needed! Take advantage while you still can!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.