Philadelphia Phillies vs San Diego Padres Prediction & Picks - MLB

USA - MLB

Philadelphia Phillies
6/3/26 18:40
San Diego Padres

Prediction:

 

Philadelphia Phillies ML

-205
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 by Matt Lowrimore in MLB Picks

A full 15-game MLB slate is scheduled for Wednesday, which includes a National League matchup between the Philadelphia Phillies and the San Diego Padres. Let’s take a look at the match statistics and predictions for this game between the Phillies and the Padres.

San Diego enters this game with a record of 32-27 and is in third place in the NL West division. The Padres lost Game 1 of this series and will look to bounce back in Game 2 by starting Walker Buehler. He has a record of 3-3 and an ERA of 4.88. To go along with his subpar ERA, Buehler has been terrible on the road this season, which gives the Phillies a good chance to win Game 2.

As for Philadelphia, they enter this game with a record of 31-29 and are in second place in the NL East. The Phillies are scheduled to start Cristopher Sanches, who has a record of 6-2 and an ERA of 1.47. The good news for the Phillies is that Sanchez has been almost unhittable when pitching at home, strengthening the chances for Philadelphia to win.

Philadelphia Phillies vs San Diego Padres Form

Table

Teams Pts P W L
7 San Diego Padres
0.542 59 32 27
14 Philadelphia Phillies
0.517 60 31 29

Philadelphia Phillies and San Diego Padres Latest Matches

Philadelphia Phillies
Philadelphia Phillies Latest matches
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 2, 2026 - MLB

Philadelphia Phillies
3 :  2
San Diego Padres

May 31, 2026 - MLB

Los Angeles Dodgers
9 :  1
Philadelphia Phillies

May 30, 2026 - MLB

Los Angeles Dodgers
3 :  4
Philadelphia Phillies

May 29, 2026 - MLB

Los Angeles Dodgers
4 :  2
Philadelphia Phillies

May 27, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies

May 26, 2026 - MLB

San Diego Padres
3 :  4
Philadelphia Phillies
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jun 2, 2026 - MLB

Philadelphia Phillies
3 :  2
San Diego Padres

May 24, 2026 - MLB

Philadelphia Phillies
1 :  3
Cleveland Guardians

May 23, 2026 - MLB

Philadelphia Phillies
3 :  0
Cleveland Guardians

May 22, 2026 - MLB

Philadelphia Phillies
0 :  1
Cleveland Guardians

May 20, 2026 - MLB

Philadelphia Phillies
4 :  9
Cincinnati Reds

May 19, 2026 - MLB

Philadelphia Phillies
1 :  4
Cincinnati Reds
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 31, 2026 - MLB

Los Angeles Dodgers
9 :  1
Philadelphia Phillies

May 30, 2026 - MLB

Los Angeles Dodgers
3 :  4
Philadelphia Phillies

May 29, 2026 - MLB

Los Angeles Dodgers
4 :  2
Philadelphia Phillies

May 27, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies

May 26, 2026 - MLB

San Diego Padres
3 :  4
Philadelphia Phillies

May 25, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies
San Diego Padres
San Diego Padres Latest matches
L L W L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Jun 2, 2026 - MLB

Philadelphia Phillies
3 :  2
San Diego Padres

May 31, 2026 - MLB

Washington Nationals
4 :  2
San Diego Padres

May 30, 2026 - MLB

Washington Nationals
9 :  4
San Diego Padres

May 29, 2026 - MLB

Washington Nationals
5 :  7
San Diego Padres

May 27, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies

May 26, 2026 - MLB

San Diego Padres
3 :  4
Philadelphia Phillies
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 27, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies

May 26, 2026 - MLB

San Diego Padres
3 :  4
Philadelphia Phillies

May 25, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies

May 24, 2026 - MLB

San Diego Padres
2 :  5
Athletics

May 23, 2026 - MLB

San Diego Padres
2 :  0
Athletics

May 22, 2026 - MLB

San Diego Padres
7 :  3
Athletics
W W W L L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 2, 2026 - MLB

Philadelphia Phillies
3 :  2
San Diego Padres

May 31, 2026 - MLB

Washington Nationals
4 :  2
San Diego Padres

May 30, 2026 - MLB

Washington Nationals
9 :  4
San Diego Padres

May 29, 2026 - MLB

Washington Nationals
5 :  7
San Diego Padres

May 17, 2026 - MLB

Seattle Mariners
3 :  8
San Diego Padres

May 16, 2026 - MLB

Seattle Mariners
4 :  7
San Diego Padres

Philadelphia Phillies against San Diego Padres : Head to Head (H2H)

Philadelphia Phillies

83 %

San Diego Padres

17 %

Jun 2, 2026 - MLB

Philadelphia Phillies
3 :  2
San Diego Padres

May 27, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies

May 26, 2026 - MLB

San Diego Padres
3 :  4
Philadelphia Phillies

May 25, 2026 - MLB

San Diego Padres
0 :  3
Philadelphia Phillies

Jul 13, 2025 - MLB

San Diego Padres
1 :  2
Philadelphia Phillies

Jul 12, 2025 - MLB

San Diego Padres
5 :  4
Philadelphia Phillies

Philadelphia Phillies - San Diego Padres Key Points

  1. Walker Buehler has an ERA of 4.88 this season
  2. Walker Buehler has an ERA of 8.04 on the road this season
  3. Cristopher Sanchez has an ERA of 1.47 this season
  4. Cristopher Sanchez has an ERA of 0.85 this season

Our Philadelphia Phillies vs San Diego Padres Prediction

The Phillies are the heavy favorite in this game; however, they still look to be the best betting option. Looking back at the starting pitchers’ home/away splits, we see that Buehler has made four starts, having allowed 14 earned runs over 15.2 innings. Sanchez, on the other hand, has made eight home starts, having allowed eight runs (five earned) over 53.0 innings. 

Both the Phillies and the Padres are near the bottom of the league in terms of runs scored per game; therefore, given the clear advantage they have on the mound with Sanchez, our Philadelphia Phillies vs San Diego Padres prediction is: Philadelphia Phillies ML.

Prediction:

 

Philadelphia Phillies ML

-205
$200 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Philadelphia Phillies vs San Diego Padres Picks