Colorado Rockies vs San Diego Padres Prediction & Picks - MLB

Prediction published on 4/23/26, 12:00 PM  by Carlos Zabala | Modified on 4/28/26 at 6:18 AM in MLB Picks

The Rockies recently split a four-game series against the Dodgers, who boasted the best record in MLB. Now, at Coors Field, they finally broke the Padres' dominance, who had already beaten them five straight games in 2016, and the Rockies entered the second game of the series as underdogs.

The Rockies won the second game 8-3. The performance was a good reaction to the first game, in which they only managed three hits. It's the Padres who are struggling offensively in this series. In two games at altitude in Colorado, only Campusano hit a home run for San Diego. As for the Rockies, Mickey Moniak is having an excellent mid-April; since the 15th of this month, he has had nine hits, raising his average above. 271 while also hitting a healthy six home runs.

The series will be decided on Thursday, and the Rockies won't return to Coors Field until May 1st. The first games of this series resulted in an under total. The sportsbook has lowered the line to 10.5 for Game 3, where Waldron will start for the Padres and Feltner for the Rockies.