Chicago Cubs vs San Diego Padres Prediction & Picks - MLB
USA - MLB
Prediction:
Chicago Cubs will win
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by Lou Aguila | in MLB Picks
The San Diego Padres look to jump back into the winner’s circle as they gun for revenge against the Chicago Cubs at Wrigley Field on Saturday.
The Padres’ unbeaten run to start the 2025 MLB season ended on Friday after bowing to the Cubs, 1-3. San Diego had no answer to Cubs’ hurler Shoto Imanaga, who conceded one run in eight innings. The Padres, batting .298/.369/.440 with 36 runs this season, will be counting on Nick Pivetta (1-0, 0.00 ERA) to get them back into their winning groove.
The Cubs have won their last four games, including Friday’s big win over the Padres. Chicago banked on their pitching all night, led by Imanaga, to contain the Padres’ high-powered offense. The Cubs hope starter Matthew Boyd can sustain their dominance on the mound in Saturday’s Game 2.
Chicago Cubs vs San Diego Padres Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
6
|
0.568 | 162 | 92 | 70 |
|
7
|
0.556 | 162 | 90 | 72 |
Chicago Cubs and San Diego Padres Latest Matches
4/6 (67%)
2/6 (33%)
Apr 4, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 28, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 4, 2025 - MLB
Mar 19, 2025 - MLB
Mar 18, 2025 - MLB
Sep 21, 2024 - MLB
Sep 19, 2024 - MLB
Sep 8, 2024 - MLB
3/6 (50%)
3/6 (50%)
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 28, 2025 - MLB
Sep 25, 2024 - MLB
5/6 (83%)
1/6 (17%)
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
6/6 (100%)
0/6 (0%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 28, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 4, 2025 - MLB
Oct 11, 2024 - MLB
Oct 6, 2024 - MLB
Oct 5, 2024 - MLB
Sep 28, 2024 - MLB
Sep 26, 2024 - MLB
Chicago Cubs against San Diego Padres : Head to Head (H2H)
33 %
67 %
Apr 4, 2025 - MLB
May 7, 2024 - MLB
May 6, 2024 - MLB
Apr 10, 2024 - MLB
Apr 8, 2024 - MLB
Mar 4, 2024 - MLB Spring Training
Chicago Cubs - San Diego Padres Key Points
- Chicago Cubs are 5-1 SU in their last 6 games.
- Chicago Cubs are 4-1 SU in their last 5 games played in April.
- San Diego are 1-4 SU in their last 5 games on the road.
- San Diego are 7-1 SU in their last 8 games.
Our Chicago Cubs vs San Diego Padres Prediction
It won’t be easy to repeat against the Padres, but I believe the Cubs have what it takes to pull it off. Boyd is coming off a strong start by blanking the Arizona Diamondbacks through five innings of a 10-6 loss. However, the key to a Cubs victory would heavily depend on the performance bullpen, who had held a 6.00+ ERA this season before shutting out the Padres in the final two innings of Game 1. Our betting prediction for San Diego Padres vs. Chicago Cubs: Cubs will win.
Prediction:
Chicago Cubs will win
All tips are fully researched and given in good faith, but profits cannot be guaranteed.