Baltimore Orioles vs San Diego Padres Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
The Baltimore Orioles eye a fifth straight victory over the San Diego Padres in Game 1 of their series.
Momentum: The Baltimore Orioles will kick off a new series feeling optimistic after winning the last two games of their series with the Seattle Mariners. The Padres also won 2 out of 3 games against the Cincinnati Reds, taking Games 1 and 3 behind clutch hitting during the late innings.
Matchup: The Orioles have won their last four meetings against the Padres. Baltimore averaged 5.67 runs per game and limited San Diego to 3.33 runs per game over their last three meetings.
Starting Pitchers: Orioles RHP Shane Baz (3-6, 4.09 ERA) has posted a 2.20 ERA over his last five starts.
Padres RHP Griffin Canning (0-4, 6.34 ERA) allowed one earned run over five innings in his latest start against the Mets on June 6. However, he has registered a 6.17 ERA across his last five mound appearances.
Hot on the Board: 61 percent of bettors have backed the Orioles to win Game 1. Caesars Sportsbooks price Baltimore at -130 moneyline and +143 to cover -1.5 runs.
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Baltimore Orioles vs San Diego Padres Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
8
|
0.531 | 81 | 43 | 38 |
|
22
|
0.464 | 84 | 39 | 45 |
Baltimore Orioles and San Diego Padres Latest Matches
2/6 (33%)
4/6 (67%)
Jun 11, 2026 - MLB
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4/6 (67%)
2/6 (33%)
Jun 11, 2026 - MLB
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3/6 (50%)
3/6 (50%)
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3/6 (50%)
3/6 (50%)
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3/6 (50%)
3/6 (50%)
Jun 10, 2026 - MLB
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1/6 (17%)
5/6 (83%)
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Baltimore Orioles against San Diego Padres : Head to Head (H2H)
80 %
20 %
Sep 3, 2025 - MLB
Sep 2, 2025 - MLB
Sep 1, 2025 - MLB
Jul 28, 2024 - MLB
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Baltimore Orioles - San Diego Padres Key Points
- San Diego is 1-4 SU in its last 5 games against Baltimore.
- San Diego is 0-5 SU in its last 5 games on the road.
- Baltimore is 12-6 SU in its last 18 games at home.
- Baltimore is 13-7 SU in its last 20 games played on a Friday when playing at home.
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Our Baltimore Orioles vs San Diego Padres Prediction
Orioles will extend their winning streak against the Padres to five games.
Baltimore will continue to lean on their offense that has generated 5.3 runs per game on a .244 BA over the last five games. Shane Baz has never allowed more than two runs in each of his last four starts.
The Padres are hitting .249 with 4 runs per game over the last five games, which are average numbers for any ball club. However, Baltimore has posted a 4.00 ERA during this five-game stretch, with their bullpen also giving up a 4.00 ERA. It may not look that bad, but in a tight ball game, surrendering 3 or 4 runs early and having a shaky bullpen to close out would put any team in a tough spot down the stretch.
Our betting prediction for the San Diego Padres vs. the Baltimore Orioles: The Orioles will win
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.