USA - NBA
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Paul Tamayo in NBA Picks
The San Antonio Spurs (11-5) visit the Portland Trail Blazers (8-10) in an NBA 2025-26 game on Wednesday, November 26, at the Moda Center.
The Blazers return home riding momentum after a 115-103 road win over the Milwaukee Bucks. Jerami Grant erupted for 35 points as Portland dominated from the free-throw line and knocked down 18 threes to finish a 2-1 road trip.
Portland continues to defy expectations this season, as they're sitting 9th in the stacked Western Conference. However, they're dealing with tons of injuries to their key players, including Jrue Holiday, Damian Lillard, Scoot Henderson, Shaedon Sharpe, and Matisse Thybulle.
As for the Spurs, they’ve cooled slightly after a hot start. San Antonio’s 11-5 record still has them near the top of the Western Conference, but they’re coming off a 111-102 road loss to the Phoenix Suns.
The Spurs built an early seven-point lead at halftime, but gave up 37 points to the Suns in the third quarter. De'Aaron Fox had a team-high 26 markers in the loss. Devin Vassell added 17, but he only shot 38.5% from the field.
San Antonio is also hampered by numerous injuries. They'll be missing the services of Victor Wembanyama, Stephon Castle, and Dylan Harper.
Limited Offer. Currently at FanDuel
San Antonio Spurs vs Portland Trail Blazers Form
Table
| Teams | % | P | W | L | Series |
|---|---|---|---|---|---|
|
5
|
0.688 | 16 | 11 | 5 | -1 |
|
9
|
0.444 | 18 | 8 | 10 | 1 |
San Antonio Spurs and Portland Trail Blazers Latest Matches
3/6 (50%)
3/6 (50%)
Nov 23, 2025 - NBA
Nov 20, 2025 - NBA
Nov 18, 2025 - NBA
Nov 16, 2025 - NBA
Nov 14, 2025 - NBA
Nov 12, 2025 - NBA
4/6 (67%)
2/6 (33%)
Nov 20, 2025 - NBA
Nov 18, 2025 - NBA
Nov 16, 2025 - NBA
Nov 14, 2025 - NBA
Nov 12, 2025 - NBA
Nov 8, 2025 - NBA
3/6 (50%)
3/6 (50%)
Nov 23, 2025 - NBA
Nov 10, 2025 - NBA
Nov 5, 2025 - NBA
Nov 2, 2025 - NBA
Oct 24, 2025 - NBA
Oct 22, 2025 - NBA
2/6 (33%)
4/6 (67%)
Nov 24, 2025 - NBA
Nov 23, 2025 - NBA
Nov 21, 2025 - NBA
Nov 19, 2025 - NBA
Nov 18, 2025 - NBA
Nov 16, 2025 - NBA
3/6 (50%)
3/6 (50%)
Nov 19, 2025 - NBA
Nov 18, 2025 - NBA
Nov 5, 2025 - NBA
Nov 3, 2025 - NBA
Oct 31, 2025 - NBA
Oct 24, 2025 - NBA
3/6 (50%)
3/6 (50%)
Nov 24, 2025 - NBA
Nov 23, 2025 - NBA
Nov 21, 2025 - NBA
Nov 16, 2025 - NBA
Nov 14, 2025 - NBA
Nov 12, 2025 - NBA
San Antonio Spurs against Portland Trail Blazers : Head to Head (H2H)
67 %
33 %
Apr 6, 2025 - NBA
Dec 21, 2024 - NBA
Dec 13, 2024 - NBA
Nov 7, 2024 - NBA
Jan 26, 2024 - NBA
Dec 29, 2023 - NBA
San Antonio Spurs - Portland Trail Blazers Key Points
- The Blazers are coming off a 115-103 win against the Milwaukee Bucks.
- The Spurs are coming off a 111-102 loss to the Phoenix Suns.
- The Blazers will miss the services of Jrue Holiday, Damian Lillard, Scoot Henderson, Shaedon Sharpe, and Matisse Thybulle.
- The Spurs will miss the services of Victor Wembanyama, Stephon Castle, and Dylan Harper.
Limited Offer. Currently at FanDuel
Our San Antonio Spurs vs Portland Trail Blazers Prediction
After a confidence-boosting road performance in Milwaukee, Portland now gets a short-handed Spurs team at home with massive NBA Cup stakes. San Antonio has been excellent overall, but without Victor Wembanyama’s rim protection and interior scoring, they lose their primary mismatch on both ends.
But don't expect the Blazers to run away with this game, as they're also dealing with a handful of injuries to their key players. Our prediction for the Portland Trail Blazers vs San Antonio Spurs match is: Spurs (+1.5) cover the spread.Grab an extra $150 for your San Antonio Spurs vs Portland Trail Blazers wager!

Get ready to experience the thrill of the game with FanDuel's exciting welcome offer, available for use on the San Antonio Spurs vs Portland Trail Blazers matchup!
A minimum bet of $5 will qualify for $150 in bonus bets if your bet wins! This offer is a golden opportunity for new users. Don't miss out on this limited-time deal to enhance your sports betting experience with some extra oomph! Jump into the action today and let FanDuel take your sports engagement to the next level!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.