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by Paul Tamayo in NBA Picks
The San Antonio Spurs visit the Dallas Mavericks in an NBA 2025-26 game on Wednesday, October 22, at the American Airlines Center.
The Cooper Flagg era in Dallas will start at home when they host the 7-foot-5 phenom Victor Wembanyama and the Spurs. Flagg, the top overall pick of this year's draft, will be flexing his two-way superstar potential in front of the Mavericks fans.
It's not just Flagg grabbing the spotlight in Dallas, though. Veteran stars Anthony Davis and Klay Thompson are raring to go, along with excellent role players like P.J. Washington and Dereck Lively II. Offseason addition D'Angelo Russell will also make his official Mavericks debut.
As for the Spurs, they're leaning on the continuous growth of Wembanyama, who averaged 24.3 points, 11.0 rebounds, and a league-best 3.8 blocks last season. Dylan Harper, the second overall pick of the 2025 NBA Draft, also looked promising during the preseason.
However, the Spurs will be missing the services of De'Aaron Fox and Jeremy Sochan on Wednesday. Fox is still recovering from a hamstring injury, while Sochan sprained his wrist just last week.
For the Mavericks, they'll be missing Kyrie Irving, who suffered a Torn ACL injury last season.
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San Antonio Spurs vs Dallas Mavericks Form
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San Antonio Spurs and Dallas Mavericks Latest Matches

4/6 (67%)
2/6 (33%)
Jul 19, 2025 - NBA Summer League
Jul 17, 2025 - NBA Summer League
Jul 14, 2025 - NBA Summer League
Jul 12, 2025 - NBA Summer League
Jul 10, 2025 - NBA Summer League
Jul 8, 2025 - NBA Summer League
4/6 (67%)
2/6 (33%)
Jul 19, 2025 - NBA Summer League
Jul 14, 2025 - NBA Summer League
Jul 12, 2025 - NBA Summer League
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Apr 13, 2025 - NBA
Apr 4, 2025 - NBA
3/6 (50%)
3/6 (50%)
Jul 17, 2025 - NBA Summer League
Jul 10, 2025 - NBA Summer League
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Jul 5, 2025 - NBA Summer League
Apr 11, 2025 - NBA
Apr 9, 2025 - NBA

2/6 (33%)
4/6 (67%)
Jul 18, 2025 - NBA Summer League
Jul 16, 2025 - NBA Summer League
Jul 14, 2025 - NBA Summer League
Jul 12, 2025 - NBA Summer League
Jul 10, 2025 - NBA Summer League
Apr 18, 2025 - NBA
3/6 (50%)
3/6 (50%)
Jul 14, 2025 - NBA Summer League
Jul 10, 2025 - NBA Summer League
Apr 11, 2025 - NBA
Apr 9, 2025 - NBA
Apr 2, 2025 - NBA
Mar 31, 2025 - NBA
2/6 (33%)
4/6 (67%)
Jul 18, 2025 - NBA Summer League
Jul 16, 2025 - NBA Summer League
Jul 12, 2025 - NBA Summer League
Apr 18, 2025 - NBA
Apr 16, 2025 - NBA
Apr 13, 2025 - NBA
San Antonio Spurs against Dallas Mavericks : Head to Head (H2H)
33 %
67 %
Jul 12, 2025 - NBA Summer League
Mar 12, 2025 - NBA
Mar 10, 2025 - NBA
Nov 16, 2024 - NBA
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Mar 19, 2024 - NBA
San Antonio Spurs - Dallas Mavericks Key Points
- Top overall pick Cooper Flagg (Mavericks) battles the second overall pick Dylan Harper (Spurs).
- Spurs All-Star Victor Wembanyama averaged 24.3 points, 11.0 rebounds, and a league-best 3.8 blocks last season.
- The Mavericks will miss the services of Kyrie Irving and Dante Exum.
- The Spurs will miss the services of De'Aaron Fox and Jeremy Sochan.
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Our San Antonio Spurs vs Dallas Mavericks Prediction
Injured star guards Kyrie Irving and De'Aaron Fox won't suit up in today's game, but there's still plenty to look forward to. Cooper Flagg and Dylan Harper, the top two picks of this year's draft, will both make their official debuts.
Then there's Victor Wembanyama, who is now in his third year in the NBA. Can the Mavericks frontline of Anthony Davis, Dereck Lively II, and Dwight Powell stop the 7-foot-5 wonder? Our prediction for the Dallas Mavericks vs San Antonio Spurs match is: Spurs (+2.5) cover the spread.Grab an extra $300 for your San Antonio Spurs vs Dallas Mavericks wager!
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
