San Antonio Spurs vs Portland Trail Blazers Prediction & Picks - NBA

USA - NBA

San Antonio Spurs
4/21/26 20:00
Portland Trail Blazers

Prediction:

 

Deni Avdija 23+ Points

-123
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 by Matt Lowrimore | in NBA Picks

The first round of the 2026 NBA Playoffs continues on Tuesday night with three games on the schedule. One of these games will be in the Western Conference and will see the San Antonio Spurs take on the Portland Trail Blazers. Let’s take a look at the match statistics and predictions for this game between the Spurs and the Trail Blazers.

Portland finds itself down 0-1 heading into Game 2, as they lost Game 1 handily on Sunday night by a score of 111-98. The Trail Blazers had no answer for Spurs superstar Victor Wembanyama, who scored a game-high 35 points. Portland was especially poor from three-point range, shooting 10 of 38 (26%). 

The only real bright spot for Portland was Deni Avdija, who led the team with 30 points on 12 of 21 shooting. Game 2 is likely not going to get any easier, so if the Trail Blazers cannot adjust its gameplan to defend Wembanyama, we are likely to see another blowout loss with Advija once again having a big game for Portland.

San Antonio Spurs vs Portland Trail Blazers Form

San Antonio Spurs and Portland Trail Blazers Latest Matches

San Antonio Spurs
San Antonio Spurs Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 12, 2026 - NBA

San Antonio Spurs
118 :  128
Denver Nuggets

Apr 10, 2026 - NBA

San Antonio Spurs
139 :  120
Dallas Mavericks

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers

Apr 6, 2026 - NBA

San Antonio Spurs
115 :  102
Philadelphia 76ers
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 12, 2026 - NBA

San Antonio Spurs
118 :  128
Denver Nuggets

Apr 10, 2026 - NBA

San Antonio Spurs
139 :  120
Dallas Mavericks

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers

Apr 6, 2026 - NBA

San Antonio Spurs
115 :  102
Philadelphia 76ers
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 4, 2026 - NBA

Denver Nuggets
136 :  134
San Antonio Spurs

Apr 2, 2026 - NBA

LA Clippers
99 :  118
San Antonio Spurs

Apr 1, 2026 - NBA

Golden State Warriors
113 :  127
San Antonio Spurs

Mar 28, 2026 - NBA

Milwaukee Bucks
95 :  127
San Antonio Spurs

Mar 25, 2026 - NBA

Memphis Grizzlies
98 :  123
San Antonio Spurs

Mar 23, 2026 - NBA

Miami Heat
111 :  136
San Antonio Spurs
Portland Trail Blazers
Portland Trail Blazers Latest matches
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 14, 2026 - NBA

Phoenix Suns
110 :  114
Portland Trail Blazers

Apr 12, 2026 - NBA

Portland Trail Blazers
122 :  110
Sacramento Kings

Apr 10, 2026 - NBA

Portland Trail Blazers
116 :  97
LA Clippers

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 12, 2026 - NBA

Portland Trail Blazers
122 :  110
Sacramento Kings

Apr 10, 2026 - NBA

Portland Trail Blazers
116 :  97
LA Clippers

Apr 2, 2026 - NBA

Portland Trail Blazers
118 :  106
New Orleans Pelicans

Mar 29, 2026 - NBA

Portland Trail Blazers
123 :  88
Washington Wizards

Mar 27, 2026 - NBA

Portland Trail Blazers
93 :  100
Dallas Mavericks

Mar 25, 2026 - NBA

Portland Trail Blazers
130 :  99
Milwaukee Bucks
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 14, 2026 - NBA

Phoenix Suns
110 :  114
Portland Trail Blazers

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers

Apr 6, 2026 - NBA

Denver Nuggets
137 :  132
Portland Trail Blazers

Mar 31, 2026 - NBA

LA Clippers
104 :  114
Portland Trail Blazers

San Antonio Spurs against Portland Trail Blazers : Head to Head (H2H)

San Antonio Spurs

50 %

Portland Trail Blazers

50 %

Apr 21, 2026 - NBA

San Antonio Spurs
103 :  106
Portland Trail Blazers

Apr 19, 2026 - NBA

San Antonio Spurs
111 :  98
Portland Trail Blazers

Apr 8, 2026 - NBA

San Antonio Spurs
112 :  101
Portland Trail Blazers

Jan 3, 2026 - NBA

San Antonio Spurs
110 :  115
Portland Trail Blazers

Nov 26, 2025 - NBA

Portland Trail Blazers
102 :  115
San Antonio Spurs

Apr 6, 2025 - NBA

Portland Trail Blazers
120 :  109
San Antonio Spurs

Players list

San Antonio Spurs
San Antonio Spurs
V. Wembanyama D. Vassell

J. Champagnie

S. Castle

D. Fox

Portland Trail Blazers
Portland Trail Blazers
D. Clingan

S. Henderson

J. Holiday

T. Camara

D. Avdija

Substitutes

San Antonio Spurs
San Antonio Spurs
K. Olynyk B. Biyombo M. Plumlee L. Kornet K. Johnson

D. Harper

L. Waters III

H. Barnes

C. Bryant

Portland Trail Blazers
Portland Trail Blazers
Y. Hansen M. Thybulle R. Williams III

B. Wesley

S. Cissoko

S. Sharpe

K. Murray

V. Krejci

J. Grant

San Antonio Spurs - Portland Trail Blazers Key Points

  1. Deni Avdija shot 12 of 21 (57%) from the field in Game 1
  2. Deni Avdija shot 2 of 5 (40%) from three-point range in Game 1
  3. Portland shot 43% from the field in Game 1
  4. Portland shot 26% from three-point range in Game 1

Our San Antonio Spurs vs Portland Trail Blazers Prediction

Once again, the Spurs are heavily favored in Game 2. With that, we are going to lean on Avdija to have another big game for Portland. Game 1 was far from Avdija’s only success against the Spurs this season. In fact, in three regular-season meetings with San Antonio, Avdija averaged 31.7 points per game.

Adding in Game 1 of this series, Avdjia is now averaging 31.5 points per game in four games against the Spurs this season. San Antonio may have its own unstoppable player with Wembanyama, but the same appears to be true for Avdija when facing the Spurs. Because of that, our San Antonio Spurs vs Portland Trail Blazers prediction is: Deni Avdija 23+ Points.

Prediction:

 

Deni Avdija 23+ Points

-123
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San Antonio Spurs vs Portland Trail Blazers Picks