St. Louis Cardinals vs Pittsburgh Pirates Prediction & Picks - MLB
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by Carlos Zabala | in MLB Picks
Absolute frenzy erupted at Busch Stadium on Tuesday as shirtless fans, waving their jerseys, witnessed Iván Herrera's three-run walk-off home run, giving the Cardinals a 9-6 victory over their divisional rivals, the Pirates. The series continues Wednesday night, with the Pirates looking to snap their four-game losing streak.
With Tuesday's win, the Cardinals improved their record to 28-19; they are proving particularly effective at closing out close games. The Panamanian's 410-foot home run secured the Cardinals' fifth walk-off victory of the year, and they improved their record in extra-inning games to 7-1.
At the plate, the Pirates racked up four runs in the fifth inning and tied the game with two more in the ninth on an RBI single by Horwitz, but in addition to Herrera's home run, his own 13 strikeouts proved to be his downfall on Tuesday. Thus, the Cardinals remain undefeated against Pittsburgh this year, winning the series 5-0 after sweeping them earlier at PNC Park.
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St. Louis Cardinals vs Pittsburgh Pirates Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
14
|
0.5 | 118 | 59 | 59 |
|
20
|
0.483 | 120 | 58 | 62 |
St. Louis Cardinals and Pittsburgh Pirates Latest Matches
4/6 (67%)
2/6 (33%)
May 19, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 19, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 6, 2026 - MLB
May 4, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 14, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
May 10, 2026 - MLB
May 9, 2026 - MLB
May 8, 2026 - MLB
1/6 (17%)
5/6 (83%)
May 19, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
2/6 (33%)
4/6 (67%)
May 17, 2026 - MLB
May 16, 2026 - MLB
May 15, 2026 - MLB
May 14, 2026 - MLB
May 13, 2026 - MLB
May 12, 2026 - MLB
3/6 (50%)
3/6 (50%)
May 19, 2026 - MLB
May 10, 2026 - MLB
May 9, 2026 - MLB
May 8, 2026 - MLB
May 7, 2026 - MLB
May 6, 2026 - MLB
St. Louis Cardinals against Pittsburgh Pirates : Head to Head (H2H)
100 %
0 %
May 19, 2026 - MLB
Apr 30, 2026 - MLB
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Apr 27, 2026 - MLB
Mar 5, 2026 - MLB Spring Training
St. Louis Cardinals - Pittsburgh Pirates Key Points
- Pirates' batting average is sixth-best in MLB at .248
- The Cardinals have a 13-11 record playing in St. Louis this season
- The Pirates have stolen 44 bases in 2016, eighth-most in MLB
- The Cardinals' collective pitching staff has a high WHIP of 1.36
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Our St. Louis Cardinals vs Pittsburgh Pirates Prediction
The last four games between the Pirates and Cardinals have resulted in an Over bet. Yesterday, the Cardinals scored 9 runs against Pittsburgh, but on two occasions this year they scored 11 and 10 runs against them in late April.
Carmen Mlodzinski will take the mound for Pittsburgh; despite allowing only 2 home runs this season, he is averaging more than one hit per inning allowed this season. McGreevy is going for his tenth start as a Cardinal in 2026, with a low ERA, but he has given up six home runs.
Our prediction for Cardinals vs Pirates is: Over 7.5 runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
