San Diego Padres vs Pittsburgh Pirates Prediction & Picks - MLB

USA - MLB

San Diego Padres
8/26/26 16:10
Pittsburgh Pirates

Prediction:

 

Over 8.5

−105
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 by Bill Christy | in MLB Picks

The Pittsburgh Pirates and the San Diego Padres will conclude their 3-game series this evening in San Diego. The Pirates will have a chance to pick up the rare road sweep if they can be successful tonight.

Both lineups have been quiet through the 1st two games of the series. In part due to some strong pitching. In game one, Braxton Ashcraft held the Padres to just 1 run on 4 hits in 6 innings. On the other side, Robbie Ray held the Pirates to 2 runs on 5 hits. Neither factored into the decision as the Pirates stole one in extra innings, 3-2.

In game two, each team had their ace on the mound, and both pitched as expected. Paul Skenes pitched 6 innings of scoreless work. Doval, Soto, and Montgomery came in to clean up the rest of the game and completed the combined shutout. Michael King was stellar for the Padres as well. He struck out 7 in 7 innings and left without allowing a run. However, Mason Miller allowed a solo shot in the 9th to Oneill Cruz, which ended up being the difference in the 1-0 Pirates win.

Today, the pitching is likely to be less of a factor. Neither starter has an ERA of 4.00 or less. Both Bubba Chandler of the Pirates and Randy Vasquez have allowed 6 runs in their last 2 starts.

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San Diego Padres vs Pittsburgh Pirates Form

Table

Teams Pts P W L
6 San Diego Padres
0.562 162 91 71
13 Pittsburgh Pirates
0.506 162 82 80

San Diego Padres and Pittsburgh Pirates Latest Matches

San Diego Padres
San Diego Padres Latest matches
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 24, 2026 - MLB

San Diego Padres
2 :  3
Pittsburgh Pirates

Aug 23, 2026 - MLB

San Diego Padres
8 :  1
Minnesota Twins

Aug 22, 2026 - MLB

San Diego Padres
7 :  5
Minnesota Twins

Aug 21, 2026 - MLB

San Diego Padres
6 :  2
Minnesota Twins

Aug 19, 2026 - MLB

New York Mets
4 :  2
San Diego Padres

Aug 18, 2026 - MLB

New York Mets
2 :  5
San Diego Padres
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 24, 2026 - MLB

San Diego Padres
2 :  3
Pittsburgh Pirates

Aug 23, 2026 - MLB

San Diego Padres
8 :  1
Minnesota Twins

Aug 22, 2026 - MLB

San Diego Padres
7 :  5
Minnesota Twins

Aug 21, 2026 - MLB

San Diego Padres
6 :  2
Minnesota Twins

Aug 12, 2026 - MLB

San Diego Padres
4 :  3
Milwaukee Brewers

Aug 11, 2026 - MLB

San Diego Padres
11 :  2
Milwaukee Brewers
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 19, 2026 - MLB

New York Mets
4 :  2
San Diego Padres

Aug 18, 2026 - MLB

New York Mets
2 :  5
San Diego Padres

Aug 17, 2026 - MLB

New York Mets
2 :  1
San Diego Padres

Aug 16, 2026 - MLB

Cleveland Guardians
0 :  5
San Diego Padres

Aug 15, 2026 - MLB

Cleveland Guardians
6 :  1
San Diego Padres

Aug 14, 2026 - MLB

Cleveland Guardians
5 :  7
San Diego Padres
Pittsburgh Pirates
Pittsburgh Pirates Latest matches
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 24, 2026 - MLB

San Diego Padres
2 :  3
Pittsburgh Pirates

Aug 23, 2026 - MLB

Los Angeles Dodgers
4 :  0
Pittsburgh Pirates

Aug 22, 2026 - MLB

Los Angeles Dodgers
4 :  3
Pittsburgh Pirates

Aug 21, 2026 - MLB

Los Angeles Dodgers
5 :  4
Pittsburgh Pirates

Aug 19, 2026 - MLB

Pittsburgh Pirates
4 :  3
Detroit Tigers

Aug 18, 2026 - MLB

Pittsburgh Pirates
4 :  1
Detroit Tigers
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 19, 2026 - MLB

Pittsburgh Pirates
4 :  3
Detroit Tigers

Aug 18, 2026 - MLB

Pittsburgh Pirates
4 :  1
Detroit Tigers

Aug 17, 2026 - MLB

Pittsburgh Pirates
5 :  8
Detroit Tigers

Aug 16, 2026 - MLB

Pittsburgh Pirates
8 :  3
Boston Red Sox

Aug 15, 2026 - MLB

Pittsburgh Pirates
0 :  4
Boston Red Sox

Aug 14, 2026 - MLB

Pittsburgh Pirates
8 :  4
Boston Red Sox
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Aug 24, 2026 - MLB

San Diego Padres
2 :  3
Pittsburgh Pirates

Aug 23, 2026 - MLB

Los Angeles Dodgers
4 :  0
Pittsburgh Pirates

Aug 22, 2026 - MLB

Los Angeles Dodgers
4 :  3
Pittsburgh Pirates

Aug 21, 2026 - MLB

Los Angeles Dodgers
5 :  4
Pittsburgh Pirates

Aug 13, 2026 - MLB

Miami Marlins
1 :  13
Pittsburgh Pirates

Aug 12, 2026 - MLB

Miami Marlins
8 :  2
Pittsburgh Pirates

San Diego Padres against Pittsburgh Pirates : Head to Head (H2H)

San Diego Padres

50 %

Pittsburgh Pirates

50 %

Aug 24, 2026 - MLB

San Diego Padres
2 :  3
Pittsburgh Pirates

Apr 8, 2026 - MLB

Pittsburgh Pirates
2 :  8
San Diego Padres

Apr 7, 2026 - MLB

Pittsburgh Pirates
7 :  1
San Diego Padres

Apr 6, 2026 - MLB

Pittsburgh Pirates
0 :  5
San Diego Padres

Jun 1, 2025 - MLB

San Diego Padres
6 :  4
Pittsburgh Pirates

May 31, 2025 - MLB

San Diego Padres
0 :  5
Pittsburgh Pirates
San Diego Padres vs Pittsburgh Pirates Picks

San Diego Padres - Pittsburgh Pirates Key Points

  1. Over is 6-0 in Vasquez’s last 6 starts as an underdog.
  2. Over is 6-0-2 in Vasquez’s last 8 starts overall.
  3. Over is 4-0 in Pirates last 4 vs. a team with a losing record.
  4. Over is 3-0-1 in Padres last 4 home games vs. a team with a losing road record.

Our San Diego Padres vs Pittsburgh Pirates Prediction

The Pirates are 3rd in the league in total runs scored. While they have not needed many to this point in the series, we believe they will break out today to give them a chance to pick up the sweep. Bubba Chandler is coming off a rocky start where he allowed 4 runs in just 4 innings. He is going to need run support in this one. While both previous games have been small totals, we like this game to regress to the mean and push the total over the number.

Our prediction for San Diego Padres vs Pittsburgh Pirates: Over 8.5

Prediction:

 

Over 8.5

−105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.