San Diego Padres vs Pittsburgh Pirates Prediction & Picks - MLB

USA - MLB

San Diego Padres
5/31/25 21:40
Pittsburgh Pirates

Prediction:

 

Pirates -1.5 Runs

+100
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 by Lou Aguila | in MLB Picks

San Diego Padres will go head-to-head with the Pittsburgh Pirates in Game 2 of their series at Petco Park.

The Padres are 4-1 in their last 5 games, averaging 5.7 runs per game but pitching a 4.21 ERA. They are two games behind the Los Angeles Dodgers (35-22) in the National League West standings. Gavin Sheet leads the team with 34 RBIs, while Manny Machado and Fernando Tatis pace the team in home runs (13) and batting average (.314).

The Pirates are 2-3 in their last 5 games to stay in the bottom of the NL Central standings with a 21-37 record. Pittsburgh has enjoyed success offensively, averaging 5.2 runs per game on a .262 batting average. Pittsburgh has also pitched a 3.98 ERA with Paul Skenes leading the team in ERA (2.15), Wins (4) and Strikeouts (77).

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San Diego Padres vs Pittsburgh Pirates Form

Table

Teams Pts P W L
7 San Diego Padres
0.556 162 90 72
26 Pittsburgh Pirates
0.438 162 71 91

San Diego Padres and Pittsburgh Pirates Latest Matches

San Diego Padres
San Diego Padres Latest matches
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 30, 2025 - MLB

San Diego Padres
3 :  2
Pittsburgh Pirates

May 27, 2025 - MLB

San Diego Padres
8 :  6
Miami Marlins

May 25, 2025 - MLB

Atlanta Braves
3 :  5
San Diego Padres

May 21, 2025 - MLB

Toronto Blue Jays
14 :  0
San Diego Padres

May 17, 2025 - MLB

San Diego Padres
1 :  4
Seattle Mariners

May 14, 2025 - MLB

San Diego Padres
5 :  1
Los Angeles Angels
W L W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 30, 2025 - MLB

San Diego Padres
3 :  2
Pittsburgh Pirates

May 27, 2025 - MLB

San Diego Padres
8 :  6
Miami Marlins

May 17, 2025 - MLB

San Diego Padres
1 :  4
Seattle Mariners

May 14, 2025 - MLB

San Diego Padres
5 :  1
Los Angeles Angels

May 12, 2025 - MLB

San Diego Padres
5 :  9
Los Angeles Angels

Apr 30, 2025 - MLB

San Diego Padres
5 :  3
San Francisco Giants
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 25, 2025 - MLB

Atlanta Braves
3 :  5
San Diego Padres

May 21, 2025 - MLB

Toronto Blue Jays
14 :  0
San Diego Padres

May 7, 2025 - MLB

New York Yankees
4 :  3
San Diego Padres

May 6, 2025 - MLB

New York Yankees
12 :  3
San Diego Padres

May 4, 2025 - MLB

Pittsburgh Pirates
0 :  4
San Diego Padres

May 3, 2025 - MLB

Pittsburgh Pirates
1 :  2
San Diego Padres
Pittsburgh Pirates
Pittsburgh Pirates Latest matches
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 30, 2025 - MLB

San Diego Padres
3 :  2
Pittsburgh Pirates

May 27, 2025 - MLB

Arizona Diamondbacks
6 :  9
Pittsburgh Pirates

May 26, 2025 - MLB

Arizona Diamondbacks
5 :  0
Pittsburgh Pirates

May 25, 2025 - MLB

Pittsburgh Pirates
5 :  6
Milwaukee Brewers

May 23, 2025 - MLB

Pittsburgh Pirates
6 :  5
Milwaukee Brewers

May 21, 2025 - MLB

Pittsburgh Pirates
3 :  1
Cincinnati Reds
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 25, 2025 - MLB

Pittsburgh Pirates
5 :  6
Milwaukee Brewers

May 23, 2025 - MLB

Pittsburgh Pirates
6 :  5
Milwaukee Brewers

May 21, 2025 - MLB

Pittsburgh Pirates
3 :  1
Cincinnati Reds

May 11, 2025 - MLB

Pittsburgh Pirates
4 :  3
Atlanta Braves

May 10, 2025 - MLB

Pittsburgh Pirates
2 :  3
Atlanta Braves

May 9, 2025 - MLB

Pittsburgh Pirates
3 :  2
Atlanta Braves
W L L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 30, 2025 - MLB

San Diego Padres
3 :  2
Pittsburgh Pirates

May 27, 2025 - MLB

Arizona Diamondbacks
6 :  9
Pittsburgh Pirates

May 26, 2025 - MLB

Arizona Diamondbacks
5 :  0
Pittsburgh Pirates

May 18, 2025 - MLB

Philadelphia Phillies
1 :  0
Pittsburgh Pirates

May 17, 2025 - MLB

Philadelphia Phillies
5 :  2
Pittsburgh Pirates

May 14, 2025 - MLB

New York Mets
0 :  4
Pittsburgh Pirates

San Diego Padres against Pittsburgh Pirates : Head to Head (H2H)

San Diego Padres

100 %

Pittsburgh Pirates

0 %

May 30, 2025 - MLB

San Diego Padres
3 :  2
Pittsburgh Pirates

May 4, 2025 - MLB

Pittsburgh Pirates
0 :  4
San Diego Padres

May 3, 2025 - MLB

Pittsburgh Pirates
1 :  2
San Diego Padres

May 2, 2025 - MLB

Pittsburgh Pirates
4 :  9
San Diego Padres

Aug 14, 2024 - MLB

San Diego Padres
8 :  2
Pittsburgh Pirates

Aug 13, 2024 - MLB

San Diego Padres
3 :  0
Pittsburgh Pirates

San Diego Padres - Pittsburgh Pirates Key Points

  1. San Diego is 4-1 SU in its last 5 games.
  2. San Diego is 13-3 SU in its last 16 games against an opponent in the National League.
  3. Pittsburgh is 0-10 SU in its last 10 games against San Diego.
  4. Pittsburgh is 3-12 SU in its last 15 games on the road.
Up to $250 to bet on San Diego Padres - Pittsburgh Pirates! 

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Our San Diego Padres vs Pittsburgh Pirates Prediction

Why you should bet on the Padres to win: San Diego is 4-1 SU in its last five games and 10-0 in their previous 10 head-to-head meetings with the Pirates. They have also managed to cover the spread in these meetings six times. Dylan Cease has been on a slump as of late, but I expect him to bounce back against the Pirates, whom he has tormented in his last three appearances against the team. Cease sports a 1.30 ERA and 4.0 strikeouts per game in his last three starts vs. the Pirates. Pirates starter Bailey Falter has posted a 0.80 ERA over his last 5 starts, but lost his 2 games against the team.

Our betting prediction for the San Diego Padres vs. Pittsburgh Pirates: Padres -1.5 Runs.

Prediction:

 

Pirates -1.5 Runs

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San Diego Padres vs Pittsburgh Pirates Picks