San Diego Padres vs Pittsburgh Pirates Prediction & Picks - MLB

USA - MLB

San Diego Padres
5/30/25 21:40
Pittsburgh Pirates

Prediction:

 

Pirates will win

 

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 by Lou Aguila | in MLB Picks

The Pittsburgh Pirates will go for their third straight win with Mitch Keller taking the mound in Friday’s series opener against the San Diego Padres at Petco Park.

The Pirates have won 3 of their last 5 games, including the previous two games of their series against the Arizona Diamondbacks. After being held scoreless in the first game, Pittsburgh responded with 19 runs between Games 2 and 3 and demonstrated a near-flawless pitching performance in a 10-1 win in Game 3. Paul Skenes shut down the D-Backs offense over 6.2 innings, while the bullpen yielded only one earned run.

The Miami Marlins snapped the Padres’ three-game win streak in the series finale, 8-10. San Diego could no longer outscore the Marlins in the final game of their series as the decision to start relief pitcher Jason Adam backfired, surrendering two earned runs in 0.2 innings.

San Diego Padres vs Pittsburgh Pirates Form

Table

Teams Pts P W L
7 San Diego Padres
0.556 162 90 72
26 Pittsburgh Pirates
0.438 162 71 91

San Diego Padres and Pittsburgh Pirates Latest Matches

San Diego Padres
San Diego Padres Latest matches
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 27, 2025 - MLB

San Diego Padres
8 :  6
Miami Marlins

May 25, 2025 - MLB

Atlanta Braves
3 :  5
San Diego Padres

May 21, 2025 - MLB

Toronto Blue Jays
14 :  0
San Diego Padres

May 17, 2025 - MLB

San Diego Padres
1 :  4
Seattle Mariners

May 14, 2025 - MLB

San Diego Padres
5 :  1
Los Angeles Angels

May 12, 2025 - MLB

San Diego Padres
5 :  9
Los Angeles Angels
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 27, 2025 - MLB

San Diego Padres
8 :  6
Miami Marlins

May 17, 2025 - MLB

San Diego Padres
1 :  4
Seattle Mariners

May 14, 2025 - MLB

San Diego Padres
5 :  1
Los Angeles Angels

May 12, 2025 - MLB

San Diego Padres
5 :  9
Los Angeles Angels

Apr 30, 2025 - MLB

San Diego Padres
5 :  3
San Francisco Giants

Apr 29, 2025 - MLB

San Diego Padres
7 :  4
San Francisco Giants
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 25, 2025 - MLB

Atlanta Braves
3 :  5
San Diego Padres

May 21, 2025 - MLB

Toronto Blue Jays
14 :  0
San Diego Padres

May 7, 2025 - MLB

New York Yankees
4 :  3
San Diego Padres

May 6, 2025 - MLB

New York Yankees
12 :  3
San Diego Padres

May 4, 2025 - MLB

Pittsburgh Pirates
0 :  4
San Diego Padres

May 3, 2025 - MLB

Pittsburgh Pirates
1 :  2
San Diego Padres
Pittsburgh Pirates
Pittsburgh Pirates Latest matches
L W W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 27, 2025 - MLB

Arizona Diamondbacks
6 :  9
Pittsburgh Pirates

May 26, 2025 - MLB

Arizona Diamondbacks
5 :  0
Pittsburgh Pirates

May 25, 2025 - MLB

Pittsburgh Pirates
5 :  6
Milwaukee Brewers

May 23, 2025 - MLB

Pittsburgh Pirates
6 :  5
Milwaukee Brewers

May 21, 2025 - MLB

Pittsburgh Pirates
3 :  1
Cincinnati Reds

May 18, 2025 - MLB

Philadelphia Phillies
1 :  0
Pittsburgh Pirates
W L W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 25, 2025 - MLB

Pittsburgh Pirates
5 :  6
Milwaukee Brewers

May 23, 2025 - MLB

Pittsburgh Pirates
6 :  5
Milwaukee Brewers

May 21, 2025 - MLB

Pittsburgh Pirates
3 :  1
Cincinnati Reds

May 11, 2025 - MLB

Pittsburgh Pirates
4 :  3
Atlanta Braves

May 10, 2025 - MLB

Pittsburgh Pirates
2 :  3
Atlanta Braves

May 9, 2025 - MLB

Pittsburgh Pirates
3 :  2
Atlanta Braves
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 27, 2025 - MLB

Arizona Diamondbacks
6 :  9
Pittsburgh Pirates

May 26, 2025 - MLB

Arizona Diamondbacks
5 :  0
Pittsburgh Pirates

May 18, 2025 - MLB

Philadelphia Phillies
1 :  0
Pittsburgh Pirates

May 17, 2025 - MLB

Philadelphia Phillies
5 :  2
Pittsburgh Pirates

May 14, 2025 - MLB

New York Mets
0 :  4
Pittsburgh Pirates

May 13, 2025 - MLB

New York Mets
2 :  1
Pittsburgh Pirates

San Diego Padres against Pittsburgh Pirates : Head to Head (H2H)

San Diego Padres

100 %

Pittsburgh Pirates

0 %

May 4, 2025 - MLB

Pittsburgh Pirates
0 :  4
San Diego Padres

May 3, 2025 - MLB

Pittsburgh Pirates
1 :  2
San Diego Padres

May 2, 2025 - MLB

Pittsburgh Pirates
4 :  9
San Diego Padres

Aug 14, 2024 - MLB

San Diego Padres
8 :  2
Pittsburgh Pirates

Aug 13, 2024 - MLB

San Diego Padres
3 :  0
Pittsburgh Pirates

Aug 12, 2024 - MLB

San Diego Padres
2 :  1
Pittsburgh Pirates

San Diego Padres - Pittsburgh Pirates Key Points

  1. San Diego is 4-8 SU in its last 12 games.
  2. San Diego is 16-4 SU in its last 20 games against an opponent in the National League.
  3. Pittsburgh is 6-3 SU in its last 9 games.
  4. Pittsburgh is 0-9 SU in its last 9 games against San Diego.

Our San Diego Padres vs Pittsburgh Pirates Prediction

Why you should bet on the Pirates to win: Mitch Keller allowed one earned run in each of his last two starts. With the Pittsburgh offense experiencing a surge over the past few days (5.2 runs per game over the last 5 games), Keller should have extra motivation to pitch well, knowing he will have enough run support to secure a win at the end of his stint. He will duel against Nick Pivetta, who surrendered one earned run over six innings in back-to-back starts vs. the Mariners and the Braves. However, Pivetta faces pressure to perform well since the Braves’ starters have given up a 7.50 ERA over the last five games.

Our betting prediction for the Pittsburgh Pirates vs. San Diego Padres: the Pirates will win

Prediction:

 

Pirates will win

 

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

San Diego Padres vs Pittsburgh Pirates Picks