New York Yankees vs Pittsburgh Pirates Prediction & Picks - MLB

USA - MLB

New York Yankees
7/21/26 19:05
Pittsburgh Pirates

Prediction:

 

Over 9 Total Runs

-105
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 by Matt Lowrimore | in MLB Picks

Every MLB team will be in action on Tuesday, which will include an Interleague matchup between the New York Yankees and the Pittsburgh Pirates. Let’s take a look at the match statistics and predictions for this game between the Yankees and the Pirates.

Pittsburgh enters this game a handful of games above .500 and is currently in fourth place in the National League Central division. For Game 2 of this series, the Pirates are scheduled to start Bubba Chandler, who has a record of 3-8 and an ERA of 4.77. To go along with his subpar numbers, Chandler has also been lackluster when pitching on the road, suggesting the Yankees will be able to take advantage.

As for New York, they enter this game as one of the best teams in the league and are currently in second place in the American League East division. The Yankees are set to start Will Warren in Game 2 of this series, who has a record of 7-4 and an ERA of 4.03.

New York Yankees vs Pittsburgh Pirates Form

Table

Teams Pts P W L
5 New York Yankees
0.56 100 56 44
10 Pittsburgh Pirates
0.515 101 52 49

New York Yankees and Pittsburgh Pirates Latest Matches

New York Yankees
New York Yankees Latest matches
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2026 - MLB

New York Yankees
8 :  5
Pittsburgh Pirates

Jul 19, 2026 - MLB

New York Yankees
2 :  1
Los Angeles Dodgers

Jul 19, 2026 - MLB

New York Yankees
2 :  8
Los Angeles Dodgers

Jul 17, 2026 - MLB

New York Yankees
1 :  2
Los Angeles Dodgers

Jul 12, 2026 - MLB

Washington Nationals
3 :  5
New York Yankees

Jul 11, 2026 - MLB

Washington Nationals
2 :  4
New York Yankees
L L L L W W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 20, 2026 - MLB

New York Yankees
8 :  5
Pittsburgh Pirates

Jul 19, 2026 - MLB

New York Yankees
2 :  1
Los Angeles Dodgers

Jul 19, 2026 - MLB

New York Yankees
2 :  8
Los Angeles Dodgers

Jul 17, 2026 - MLB

New York Yankees
1 :  2
Los Angeles Dodgers

Jul 5, 2026 - MLB

New York Yankees
1 :  6
Minnesota Twins

Jul 4, 2026 - MLB

New York Yankees
4 :  11
Minnesota Twins
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 12, 2026 - MLB

Washington Nationals
3 :  5
New York Yankees

Jul 11, 2026 - MLB

Washington Nationals
2 :  4
New York Yankees

Jul 10, 2026 - MLB

Washington Nationals
3 :  5
New York Yankees

Jul 9, 2026 - MLB

Tampa Bay Rays
4 :  12
New York Yankees

Jul 8, 2026 - MLB

Tampa Bay Rays
3 :  0
New York Yankees

Jul 7, 2026 - MLB

Tampa Bay Rays
6 :  4
New York Yankees
Pittsburgh Pirates
Pittsburgh Pirates Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2026 - MLB

New York Yankees
8 :  5
Pittsburgh Pirates

Jul 19, 2026 - MLB

Cleveland Guardians
1 :  7
Pittsburgh Pirates

Jul 18, 2026 - MLB

Cleveland Guardians
5 :  3
Pittsburgh Pirates

Jul 18, 2026 - MLB

Cleveland Guardians
1 :  7
Pittsburgh Pirates

Jul 12, 2026 - MLB

Pittsburgh Pirates
14 :  5
Milwaukee Brewers

Jul 11, 2026 - MLB

Pittsburgh Pirates
3 :  2
Milwaukee Brewers
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 12, 2026 - MLB

Pittsburgh Pirates
14 :  5
Milwaukee Brewers

Jul 11, 2026 - MLB

Pittsburgh Pirates
3 :  2
Milwaukee Brewers

Jul 11, 2026 - MLB

Pittsburgh Pirates
7 :  6
Milwaukee Brewers

Jul 9, 2026 - MLB

Pittsburgh Pirates
5 :  10
Atlanta Braves

Jul 8, 2026 - MLB

Pittsburgh Pirates
0 :  3
Atlanta Braves

Jul 7, 2026 - MLB

Pittsburgh Pirates
12 :  4
Atlanta Braves
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2026 - MLB

New York Yankees
8 :  5
Pittsburgh Pirates

Jul 19, 2026 - MLB

Cleveland Guardians
1 :  7
Pittsburgh Pirates

Jul 18, 2026 - MLB

Cleveland Guardians
5 :  3
Pittsburgh Pirates

Jul 18, 2026 - MLB

Cleveland Guardians
1 :  7
Pittsburgh Pirates

Jul 5, 2026 - MLB

Washington Nationals
5 :  11
Pittsburgh Pirates

Jul 4, 2026 - MLB

Washington Nationals
1 :  7
Pittsburgh Pirates

New York Yankees against Pittsburgh Pirates : Head to Head (H2H)

New York Yankees

67 %

Pittsburgh Pirates

33 %

Jul 20, 2026 - MLB

New York Yankees
8 :  5
Pittsburgh Pirates

Mar 9, 2026 - MLB Spring Training

New York Yankees
3 :  5
Pittsburgh Pirates

Feb 23, 2026 - MLB Spring Training

Pittsburgh Pirates
2 :  6
New York Yankees

Apr 6, 2025 - MLB

Pittsburgh Pirates
5 :  4
New York Yankees

Apr 5, 2025 - MLB

Pittsburgh Pirates
4 :  10
New York Yankees

Apr 4, 2025 - MLB

Pittsburgh Pirates
4 :  9
New York Yankees
New York Yankees vs Pittsburgh Pirates Picks

New York Yankees - Pittsburgh Pirates Key Points

  1. Bubba Chandler has an ERA of 4.77 this season
  2. Bubba Chandler has an ERA of 4.88 on the road this season
  3. Will Warren has an ERA of 4.03 this season
  4. Will Warren has an ERA of 3.80 at home this season

Our New York Yankees vs Pittsburgh Pirates Prediction

The Yankees are the clear favorite in this game; however, they still look to be the best betting option. This is largely because of the home/away splits between the two starting pitchers. Chandler has made 11 away appearances (10 starts), in which he has allowed 35 runs (30 earned) over 55.1 innings. Warren, on the other hand, has made nine home starts, where he has allowed 29 runs (20 earned) over 47.1 innings.

Further, both Chandler and Warren have had a couple of rough starts in July, not to mention that the Pirates’ offense ranks second in runs per game, while the Yankees’ offense ranks 10th in the same category. Given this, our New York Yankees vs Pittsburgh Pirates prediction is: Over 9 Total Runs.

Prediction:

 

Over 9 Total Runs

-105
$1000 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.