Houston Astros vs Pittsburgh Pirates Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
The surging Pittsburgh Pirates will be aiming to make it five wins on the bounce when they face the Houston Astros at Daikin Park on Wednesday evening.
The Pirates emerged 10-6 victors in the opening game of this three match series, thanks to an explosive offensive display that saw Oneil Cruz and Brandon Lowe smash three run homers and Endy Rodríguez chip in with a two run shot.
That victory improved the Pirates' record to 33-28 and puts them just four games behind the Brewers at the top of the NL Central division. After a slow start to the campaign, hopes are rising that the Pirates can mount a serious bid for a postseason place.
Meanwhile, the Astros now have a dismal 27-35 season record, and barring a dramatic turnaround in fortunes, their postseason hopes appear to be over for another season.
Limited Offer. Currently at Fanatics
Houston Astros vs Pittsburgh Pirates Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
8
|
0.541 | 61 | 33 | 28 |
|
23
|
0.435 | 62 | 27 | 35 |
Houston Astros and Pittsburgh Pirates Latest Matches
3/6 (50%)
3/6 (50%)
Jun 2, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 28, 2026 - MLB
May 27, 2026 - MLB
2/6 (33%)
4/6 (67%)
Jun 2, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 17, 2026 - MLB
May 16, 2026 - MLB
5/6 (83%)
1/6 (17%)
May 28, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
May 25, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
4/6 (67%)
2/6 (33%)
Jun 2, 2026 - MLB
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 28, 2026 - MLB
May 27, 2026 - MLB
4/6 (67%)
2/6 (33%)
May 31, 2026 - MLB
May 30, 2026 - MLB
May 29, 2026 - MLB
May 28, 2026 - MLB
May 27, 2026 - MLB
May 26, 2026 - MLB
4/6 (67%)
2/6 (33%)
Jun 2, 2026 - MLB
May 24, 2026 - MLB
May 23, 2026 - MLB
May 22, 2026 - MLB
May 21, 2026 - MLB
May 20, 2026 - MLB
Houston Astros against Pittsburgh Pirates : Head to Head (H2H)
50 %
50 %
Jun 2, 2026 - MLB
Mar 17, 2026 - MLB Spring Training
Feb 28, 2026 - MLB Spring Training
Jun 5, 2025 - MLB
Jun 4, 2025 - MLB
Jun 3, 2025 - MLB
Houston Astros - Pittsburgh Pirates Key Points
- Pittsburgh are on a 4 game winning run
- The Astros have lost 4 of their last 5 at home
- The Pirates have won 7 of their last 9 matches
- Houston are 13-17 at home this season
Limited Offer. Currently at Fanatics
Our Houston Astros vs Pittsburgh Pirates Prediction
Pittsburgh's offense is on fire at the moment, and it is hard to see the Astros slowing them down on Wednesday night.
Houston have shown glimpses of quality over the last month, but they have struggled for consistency, and lack the pitching game to cause problems for the top teams in the league.
Oneil Cruz, Endy Rodríguez and Brandon Lowe are all in excellent form for the Pirates, so not only are we tipping the visitors to win, we think they will do so by a healthy margin.
Our prediction for Houston Astros vs Pittsburgh Pirates is: Pirates (-1) to win.
A Bonus for the 2026 World cup for Houston Astros vs Pittsburgh Pirates!
Looking to bet on Houston Astros vs Pittsburgh Pirates? Now's a great time to take advantage of the Fanatics Sportsbook welcome offer.
Signing up today will grant you up to $350 which can be used to bet on this MLB match. It's one of the most unique bonuses on the market currently, so take advantage today!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
