Cincinnati Reds vs Pittsburgh Pirates Prediction & Picks - MLB
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by Matt Lowrimore | in MLB Picks
As part of the 15-game MLB slate on Wednesday, one of the games will feature an NL Central matchup between the Cincinnati Reds and the Pittsburgh Pirates. Let’s take a look at the match statistics and predictions for this game between the Reds and the Pirates.
Pittsburgh is off to a rough start this season, especially Paul Skenes, who is scheduled to make his second start of the season in this matchup. Skenes could not have had a worse 2026 debut, as he allowed five earned runs and failed to make it out of the first inning. As bad as he looked, Skenes should still be considered a top pitcher in the National League and should be able to bounce back here.
Cincinnati, on the other hand, has had a solid start to the season and will look to continue that with Andrew Abbott starting on Wednesday. Abbott will be making his second start of the season, coming off a 6.0-inning outing where he did not allow a run.
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Cincinnati Reds vs Pittsburgh Pirates Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
16
|
0.494 | 83 | 41 | 42 |
|
20
|
0.481 | 81 | 39 | 42 |
Cincinnati Reds and Pittsburgh Pirates Latest Matches
3/6 (50%)
3/6 (50%)
Mar 31, 2026 - MLB
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Mar 24, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 31, 2026 - MLB
Mar 30, 2026 - MLB
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Mar 21, 2026 - MLB Spring Training
1/6 (17%)
5/6 (83%)
Mar 24, 2026 - MLB Spring Training
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2/6 (33%)
4/6 (67%)
Mar 31, 2026 - MLB
Mar 30, 2026 - MLB
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
Mar 23, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
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2/6 (33%)
4/6 (67%)
Mar 31, 2026 - MLB
Mar 30, 2026 - MLB
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
Mar 20, 2026 - MLB Spring Training
Cincinnati Reds against Pittsburgh Pirates : Head to Head (H2H)
50 %
50 %
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Cincinnati Reds - Pittsburgh Pirates Key Points
- Skenes had an ERA of 0.00 vs Cincinnati in 2025
- Abbott had an ERA of 1.80 vs Pittsburgh in 2025
- Skenes had an ERA of 2.15 on the road in 2025
- Abbott had an ERA of 2.39 at home in 2025
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Our Cincinnati Reds vs Pittsburgh Pirates Prediction
Pittsburgh is the heavy favorite in this game; however, the under looks to be the best betting option. It is a fact that Skenes looked terrible in his first start, but that should not continue. Last season, Skenes was lights out against the Reds, posting an ERA of 0.00 against them, while also posting an ERA of 2.15 on the road.
Cincinnati’s Abbott, on the other hand, had an ERA of 1.80 against Pittsburgh in 2025 and an ERA of 2.39 at home. Given the splits shown by both starting pitchers last season, this game has the makings of a pitcher’s duel. For that reason, our Cincinnati Reds vs Pittsburgh Pirates prediction is: Under 7.5 Total Runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
