Cincinnati Reds vs Pittsburgh Pirates Prediction & Picks - MLB
USA - MLB
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by Carlos Zabala | in MLB Picks
We'll have the first divisional matchup for both teams when the Reds stay at Great American Ball Park for the first of a three-game series against the Pirates. Cincinnati is the -125 favorite in the betting odds.
The Pirates put their opening day nightmare, in which their ace, Skenes, didn't last an inning, behind them. Following that incident, they made adjustments, such as temporarily removing O'Neil Cruz from center field. Finally, they left Citi Field with a positive feeling after winning 4-3 on Sunday in a game where Lindor was thrown out at home plate on a key play and where Lowe hit his third home run of the young season.
Chase Burns will start for the Reds, having earned a spot in the starting rotation after Lodolo's injury. He's 23 years old, but he'll be ready to continue the Reds' momentum, having taken the last two close games of the opening series against the Red Sox. The Reds won Sunday's game thanks to Eugenio Suárez's first home run of the season, his first with the Reds since 2026, after receiving a $15 million contract and winning the WBC with Venezuela a few weeks prior.
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Cincinnati Reds vs Pittsburgh Pirates Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
16
|
0.494 | 83 | 41 | 42 |
|
20
|
0.481 | 81 | 39 | 42 |
Cincinnati Reds and Pittsburgh Pirates Latest Matches
2/6 (33%)
4/6 (67%)
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
Mar 21, 2026 - MLB Spring Training
Mar 18, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
1/6 (17%)
5/6 (83%)
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 18, 2026 - MLB Spring Training
Mar 16, 2026 - MLB Spring Training
2/6 (33%)
4/6 (67%)
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 18, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
1/6 (17%)
5/6 (83%)
Mar 29, 2026 - MLB
Mar 28, 2026 - MLB
Mar 26, 2026 - MLB
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 16, 2026 - MLB Spring Training
Cincinnati Reds against Pittsburgh Pirates : Head to Head (H2H)
50 %
50 %
Sep 25, 2025 - MLB
Sep 24, 2025 - MLB
Sep 23, 2025 - MLB
Aug 10, 2025 - MLB
Aug 9, 2025 - MLB
Aug 8, 2025 - MLB
Cincinnati Reds - Pittsburgh Pirates Key Points
- Both of the Reds' victories in 2026 were by one run
- The Pirates are averaging 11 hits per game
- The Reds are paying +550 to win their division, while the Pirates are paying +600.
- The Pirates have won 6 of their last 9 games against the Reds
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Our Cincinnati Reds vs Pittsburgh Pirates Prediction
Braxton Ashcraft will start the Pirates' fourth game; in 2025, he worked his way up between Triple-A and the majors, pitching a high number of innings. In his last preseason start, he pitched well, throwing three scoreless innings on just 38 pitches.
This season, the Pirates are built to surprise and finally avoid finishing at the bottom of their division. Skenes leads the pitching staff, but he's followed by a couple of young pitchers to watch, and the lineup has improved compared to last year.
Our prediction for Reds vs Pirates is: Pirates ML.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
