Chicago Cubs vs Pittsburgh Pirates Prediction & Picks - MLB

USA - MLB

Chicago Cubs
4/11/26 14:20
Pittsburgh Pirates

Prediction:

 

Over 5.5 runs.

-179
$200 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Stephen Abiola | in MLB Picks

Chicago Cubs (6-7) and Pittsburgh Pirates (8-5) will clash in the NL Central on Saturday evening at Wrigley Field. The Pirates are coming off a 2-0 win over the Cubs in the series opener to make it seven wins in their last 10 matches. Bryan Reynolds had a 2-run homer while Carmen Mlodzinski pitched a 6-hit ball into the sixth inning to help the Pirates shut down the hosts. This win also puts them second in the division.

Chicago Cubs, meanwhile, find themselves languishing at the bottom of the NL Central, 2.0 games behind the Brewers and the Pirates. They’ve been inconsistent so far after dropping five of their last 10 matches. The Cubs have failed to maximize their home assignments this season, having lost four of their seven matches. Still, they should be glad to be back home in this series after a six-game road trip.

Chicago Cubs vs Pittsburgh Pirates Form

Table

Teams Pts P W L
7 Chicago Cubs
0.542 83 45 38
16 Pittsburgh Pirates
0.494 83 41 42

Chicago Cubs and Pittsburgh Pirates Latest Matches

Chicago Cubs
Chicago Cubs Latest matches
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 10, 2026 - MLB

Chicago Cubs
0 :  2
Pittsburgh Pirates

Apr 8, 2026 - MLB

Tampa Bay Rays
2 :  6
Chicago Cubs

Apr 7, 2026 - MLB

Tampa Bay Rays
2 :  9
Chicago Cubs

Apr 6, 2026 - MLB

Tampa Bay Rays
6 :  4
Chicago Cubs

Apr 5, 2026 - MLB

Cleveland Guardians
6 :  5
Chicago Cubs

Apr 5, 2026 - MLB

Cleveland Guardians
0 :  1
Chicago Cubs
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 10, 2026 - MLB

Chicago Cubs
0 :  2
Pittsburgh Pirates

Apr 1, 2026 - MLB

Chicago Cubs
6 :  2
Los Angeles Angels

Mar 31, 2026 - MLB

Chicago Cubs
0 :  2
Los Angeles Angels

Mar 30, 2026 - MLB

Chicago Cubs
7 :  2
Los Angeles Angels

Mar 29, 2026 - MLB

Chicago Cubs
3 :  6
Washington Nationals

Mar 28, 2026 - MLB

Chicago Cubs
10 :  2
Washington Nationals
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 8, 2026 - MLB

Tampa Bay Rays
2 :  6
Chicago Cubs

Apr 7, 2026 - MLB

Tampa Bay Rays
2 :  9
Chicago Cubs

Apr 6, 2026 - MLB

Tampa Bay Rays
6 :  4
Chicago Cubs

Apr 5, 2026 - MLB

Cleveland Guardians
6 :  5
Chicago Cubs

Apr 5, 2026 - MLB

Cleveland Guardians
0 :  1
Chicago Cubs

Apr 3, 2026 - MLB

Cleveland Guardians
4 :  1
Chicago Cubs
Pittsburgh Pirates
Pittsburgh Pirates Latest matches
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 10, 2026 - MLB

Chicago Cubs
0 :  2
Pittsburgh Pirates

Apr 8, 2026 - MLB

Pittsburgh Pirates
2 :  8
San Diego Padres

Apr 7, 2026 - MLB

Pittsburgh Pirates
7 :  1
San Diego Padres

Apr 6, 2026 - MLB

Pittsburgh Pirates
0 :  5
San Diego Padres

Apr 5, 2026 - MLB

Pittsburgh Pirates
8 :  2
Baltimore Orioles

Apr 4, 2026 - MLB

Pittsburgh Pirates
3 :  2
Baltimore Orioles
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 8, 2026 - MLB

Pittsburgh Pirates
2 :  8
San Diego Padres

Apr 7, 2026 - MLB

Pittsburgh Pirates
7 :  1
San Diego Padres

Apr 6, 2026 - MLB

Pittsburgh Pirates
0 :  5
San Diego Padres

Apr 5, 2026 - MLB

Pittsburgh Pirates
8 :  2
Baltimore Orioles

Apr 4, 2026 - MLB

Pittsburgh Pirates
3 :  2
Baltimore Orioles

Apr 3, 2026 - MLB

Pittsburgh Pirates
5 :  4
Baltimore Orioles
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 10, 2026 - MLB

Chicago Cubs
0 :  2
Pittsburgh Pirates

Apr 1, 2026 - MLB

Cincinnati Reds
3 :  8
Pittsburgh Pirates

Mar 31, 2026 - MLB

Cincinnati Reds
3 :  8
Pittsburgh Pirates

Mar 30, 2026 - MLB

Cincinnati Reds
2 :  0
Pittsburgh Pirates

Mar 29, 2026 - MLB

New York Mets
3 :  4
Pittsburgh Pirates

Mar 28, 2026 - MLB

New York Mets
4 :  2
Pittsburgh Pirates

Chicago Cubs against Pittsburgh Pirates : Head to Head (H2H)

Chicago Cubs

83 %

Pittsburgh Pirates

17 %

Apr 10, 2026 - MLB

Chicago Cubs
0 :  2
Pittsburgh Pirates

Sep 17, 2025 - MLB

Pittsburgh Pirates
4 :  8
Chicago Cubs

Sep 16, 2025 - MLB

Pittsburgh Pirates
1 :  4
Chicago Cubs

Sep 15, 2025 - MLB

Pittsburgh Pirates
0 :  4
Chicago Cubs

Aug 17, 2025 - MLB

Chicago Cubs
4 :  3
Pittsburgh Pirates

Aug 16, 2025 - MLB

Chicago Cubs
3 :  1
Pittsburgh Pirates

Chicago Cubs - Pittsburgh Pirates Key Points

  1. The Cubs are 5-1 in their last six meetings with the Pirates.
  2. The total runs went over 5.5 in four of the last six Chicago Cubs matches.
  3. The total runs went over 5.5 runs in six of the last nine Pittsburgh Pirates matches.
  4. The total runs went over 5.5 runs in 16 of the last 18 Pittsburgh Pirates away games.

Our Chicago Cubs vs Pittsburgh Pirates Prediction

The Cubs are -175 on the moneyline, as they look to bounce back from their recent misfortune. We expect them to have a breakout outing at the dish, having scored 24 runs in their four games before their 2-0 loss against the Pirates. The visitors have also shown they can do some damage, thanks to their potent roster, which registered some big wins in their last three series. The Cubs will start Edward Cabrera (1-0, 0.00 ERA, and 9 strikeouts), whereas the Pirates will have Braxton Ashcraft (1-1, 2.22 ERA, and 11 strikeouts) on the mound. Both are exceptional pitchers, although Cabrera should give the home side an edge tonight.

Our prediction for Chicago Cubs vs Pittsburgh Pirates: Over 5.5 runs.

Prediction:

 

Over 5.5 runs.

-179
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Chicago Cubs vs Pittsburgh Pirates Picks